* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download cell
Survey
Document related concepts
Tissue engineering wikipedia , lookup
Extracellular matrix wikipedia , lookup
Cell growth wikipedia , lookup
Cell nucleus wikipedia , lookup
Signal transduction wikipedia , lookup
Cell culture wikipedia , lookup
Cellular differentiation wikipedia , lookup
Cell membrane wikipedia , lookup
Cell encapsulation wikipedia , lookup
Cytokinesis wikipedia , lookup
Organ-on-a-chip wikipedia , lookup
Transcript
CHAPTER FOUR: CELL STRUCTURE AND FUNCTION 7.1 History of the Cell Robert Hooke (1665) – Used compound scope to examine thin cork slices. Coined the term “cell” referring to the many little boxes. Actually saw dead plant cells Anton van Leeuwenhoek (1673) – Use simple scope (one lens), observed first living cells. Matthias Schleiden (1838) and Theodor Schwann stated that all plants and animals (respectively) are made up of cells . Rudolph Virchow (1855) – cells come only from other cells. The Cell Theory All living things are made up of cells Cells are the basic unit of structure and function in all living things Cells come from pre-existing cells 7.2 Introduction to Cells Side Length Surface Area Volume Surface area to Volume ratio 1mm 6mm2 1mm3 6 to 1 2mm 24mm2 8mm3 3 to 1 3mm 54mm2 27mm3 2 to 1 Cells vary by: 1. Size – Range from 2m (giraffe nerve cell from leg to spine) to .2um (bacteria) Limited by the ratio between outer surface area and their volume. As the surface area to volume ratio decreases, it makes it difficult for nutrients and waste to get around cell. 2. Shape – Structure is related to function Red Blood Cells are biconcave disks Nerve cells are electrical wires Skin cells (Epithelial cells) are flat White Blood cells creep along and squeeze into all areas 3. Internal Organization – Organelles – internal structures in a cell, each with a specific function All cells contain: a. cell membrane – thin membrane, porous to certain compounds b. cytoplasm – gel-like substance where organelles, ions, organic compounds are suspended in it c. ribosomes – Protein factories in cells d. DNA Compare/Contrast Types of cells 1. Prokaryotic cells – cells that lack a nucleus and membrane bound organelles - two Groups: Bacteria and Archaebacteria - have a cell wall, cell membrane, cytoplasm, DNA, ribosomes - enzymes and other molecules are suspended in cytoplasm 2. Eukaryotic Cells – contain a membrane bound nucleus and membrane bound organelles - much more complex cell - all cells other than bacteria -includes these groups: Protists, Fungus, Animals and Plants Nucleus 7.3 Cell Parts and Functions Three main components: nucleus cell membrane cellular organelles Cell membrane Cell Membrane – separates the cell’s internal environment from the external environment. - allows for the passage of some substances based on size and concentration selectively permeable Phospholipid Bilayer Of Cell Membrane made up of a bilipid layer (lipid bilayer) – two layers of phospholipids with proteins floating through it; referred to as Fluid Mosaic Model tails of phospholipids are hydrophobic while the heads are hydrophilic – WHY??? Peripheral membrane proteins - do not penetrate the hydrophobic core of the membrane; can be easily removed without destroying the membrane structure. Integral membrane proteins - fully incorporated into the membrane and are in contact with both the inside and the outside of the cell; some act as channels or tunnels for the transport of substances, others have Integral carbohydrates attached to them – recognition Peripheral protein sites protein In the "fluid mosaic model" of membrane structure, the membrane is a fluid phospholipid bilayer in which protein molecules are either partially or wholly embedded. These layers easily move around. Cellular Organelles Cytoplasm - Made of gelatinous material where nutrients and minerals are carried in solution Typical Animal Cell Typical Plant Cell Mitochondria - powerhouse of the cells. - where cellular respiration occurs =glucose is broken down to release energy (in the form of ATP) to the cell - found in greater numbers in cells such as muscle cells and liver cells; double membrane with internal cristae (folds) to increase surface area Cristae Double Membrane Ribosomes most numerous organelle,site of protein synthesis (where proteins are made) not membrane bound therefore, they are in prokaryotic cells. made up of RNA and protein. may be free floating in cytoplasm or attached on endoplasmic reticulum Endoplasmic Reticulum – channels or passageways in the cell; two types of ER: 1 – Rough with ribosomes attached for the production and distribution of proteins 2 – Smooth – Synthesis of steroids in gland cells, Ca++ regulation in muscle cells 1 2 3 4 5 6 7 8 - 10 Nucleus Nuclear Envelope Rough endoplasmic reticulum (RER) Smooth endoplasmic reticulum SER) Ribosome on the rough ER Proteins that are transported Transport vesicle Golgi apparatus Golgi Apparatus (Bodies) o stack of smooth flat sacs o processing, packaging and secreting organelle of the cell o much like a processing & exporting plant Work in close association with ER Lysosomes single membrane sacs; are the cells' garbage disposal system breakdown worn out organelles such as mitochondria and produce hydrolytic enzymes to that degrade DNA, proteins, lipids and carbohydrates responsible for the un-webbing of hands of fetus while developing in utero Cytoskeleton - network of protein strands that provide support and mobility of organelles in cytoplasm Two components of cytoskeleton - microfilaments – made of actin (protein threads); involved with cellular movement and muscle contractions - microtubules – larger structures; involved in cell division, make up flagella and cilia, also make up spindle fibers that assist in chromosome migration during cell division Cilia and Flagella extensions from cell membrane assist in movement cilia - when short and multiple numbers. covering of Paramecium, lining of respiratory tract and nasal passages. flagella- long and usually only 1 to a few; sperm cells, Euglena; used for propulsion Nucleus only in Eukaryotic cells stores hereditary information in DNA surrounded by a double nuclear envelope; nuclear pores perforate membrane chromatin - strands of a combination of DNA and protein within nucleus; these will later become chromosomes. nucleolus (1 or more) produces ribosomes 7.4 Plant Cells Are eukaryotic and have most of the same organelles as animal cells except: 1.Cell walls made up of cellulose and pectin (glue between walls) gives cells rigidity, protection & support. is also porous 2. Vacuoles - store enzymes, food, water and wastes - huge water vacuole in plant cells - gives plant cell “turgor” (full of water and fully supported) – 90% of cells may be water - some contain metabolic wastes which may be toxic to other organisms (poison ivy) 3. Plastids - double membrane, DNA containing to store starch, fats or pigments such as chlorophyll - chloroplast – where photosynthesis occurs; made up of stacks called thylakoids, where energy conversion occurs - leucoplast - store starch Typical Animal Cell 1. _______________ 2. _______________ 3. _______________ (Dots) 4. _______________ 5. _______________ 6. _______________ 7. _______________ 8. _______________ 9. _______________ 10._______________ 11._______________ 12._______________ 13._______________ Typical Plant Cell Cheek Cells Elodea Onion Cells Potato Cells Organelle Function Plant Cells Animal Cells Mitochondria Site of cellular respiration - transfer of energy - Folds called Cristae Yes Yes Ribosomes Site of Protein synthesis Yes Yes Endoplasmic Reticulum Rough - Protein packaging & transport site Smooth - Sythesis of lipids Yes Yes Golgi Apparatus Processing & packaging center for cell secretions Few Many Lysosomes Produce hydrolytic enzymes Few Many Cytoskeleton Network of protein filaments - keep cell's shape and for movement Yes Yes Microfilaments & microtubules Support, movement and cell division Yes Yes Cilia & Flagella Cell movement & circulation Cilia - many & short, Flagella 1or 2 & long Yes Yes Nucleolus Production of ribosomes Yes Yes Nucleus Contains DNA, synthesizes RNA & Ribosomes Yes Yes Chromatin DNA & protein - genetic information Yes Yes Cell Wall Outmost layer of plant cell - support & protection Made of cellulose & pectin glue between walls Yes No Vacuole Stores enzymes, wastes, water & food Large water in plants - support Yes, large water vacuole Many Plastid Stores food and pigments - Chloroplasts (photosynthesis) & leucoplasts (stores starch) Yes No Centrioles Microtubules that function during cell division No Yes Cell Membrane Selectively permeable - made of a bilipid layer & proteins Yes Yes