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Name:_________________________________ Due April 14, 2010 Chapter 3- KEY 1. Define the terms “monomer” and “polymer.” Connect these two terms by using them in a complete sentence (.5pt). Monomer- chemical subunit that serves as a building block of a polymer. Polymer- large molecule consisting of many molecular subunits (monomers) covalently joined together in a chain. A polymer consists of multiple subunits called monomers. 2. List the four main types of macromolecules found in your body (.5pt). Lipid, Proteins, Carbohydrates, Nucleic Acids 3. What are the monomers and polymers of three of the four types of macromolecules (lipids are excluded)? Provide the broad name (as opposed to an example) for the monomer and polymer of each macromolecule (1pt). Lipids- no true monomer, but fatty acids and glycerol Proteins-amino acids Carbohydrates-Monosaccharide Nucleic Acids-nucleotides -1- 4. Name the 6 functional groups of organic compounds and include their chemical formula (.5pt). Hydroxyl- OH Carbonyl- C=O Carboxyl- COOH Amino- NH2 Phosphate OPO32Methyl CH3 5. What are the two “trademark” functional groups that make up a sugar? (.5pt) Hydroxyl group and carbonyl group 6. Describe what an enzyme is. Include it is made of (i.e., proteins, carbohydrates, lipids or nucleic acids) its function and how it influences chemical reactions in cells (1pts). An enzyme is a protein that acts as a chemical catalyst that speeds up reactions in cells. -2- 7. What type of reaction creates polymers? (.5pt) Dehydration 8. How many water molecules are created when 6 monomers are combined into a polymer? (.5pt) 5 9. Hydrocarbons…….(.5pt) A) are inorganic compounds. B) are composed of carbon atoms that are attached to hydrogen skeletons. C) contain only carbon and hydrogen atoms. D) consist of atoms linked exclusively by single bonds. E) All of the choices are correct. 10. Describe the difference between saturated and unsaturated fats (.5pt). Saturated fats have the maximum number of H possible and no double bonds. Unsaturated fats have less than the maximum number of H and include double bonds -3- 11. Are the following molecules isomers? (.5pt) A. & B. C. -4- 12. Where in the body are phospholipids found and why are they suited for that purpose? (.5pt) Phospholipids are found in the cell membrane. Their hydrophilic and hydrophobic properties of the molecule make it suitable for use in a membrane as they act to form a barrier. 13. Name the 4 levels of structure in proteins and describe each level (1pts). Primary- unique sequence of amino acids Secondary- polypeptide folds and coils into an alpha helix or a pleated sheet Tertiary- overall three-dimensional shape of the protein Quaternary- protein subunits interact 14. What are the roles of DNA and RNA in a cell? What base pairs do they each use? (1pt) DNA contains the genetic information for inheritance. Base pairs are A,T,C,G RNA works as an intermediary between DNA and protein synthesis. Base pairs are A, U, C, G -5- 15. Explain how heat, pH and other environmental factors interfere with protein function (.5pt). Heat, pH and other environmental factors can cause a protein to denature, which is when the shape of the protein is altered, affecting its function. 16. Describe the differences in bonding of lipids, proteins, and carbohydrates (.5pt). Lipids consist mainly of C and H held via non-polar covalent bonds Proteins consist of functional groups covalently bonded to a central C Carbohydrates tend to bond in rings -6- Ch 4 1. What is meant by a large surface area to volume ratio? How does this impact cells? (1pt) When something has a large surface area to volume ration it means that the object has a large amount of surface area per unit of volume. For cells, this ratio impacts how large they can be, transportation of nutrients and wastes in and out, and diffusion distance inside the cell. 2. List the differences between Prokaryotic and Eukaryotic cells (.5pt) Prokaryotic Smaller No nuclear membrane Eukaryotic Larger True nucleus, consisting of nuclear membrane & nucleoli Membrane-enclosed organelles Cell wall Absent Present Usually present; chemically complex When present, chemically simple Plasma membrane Present Present Cytoplasm Ribosomes Chromosome (DNA) arrangement Present Present Single circular chromosome; lacks histones No meiosis; transfer of DNA fragments through cell-to-cell contact Present Present Multiple linear chromosomes with histones Involves meiosis Size of cell Nucleus Sexual reproduction 3. How do DNA and chromosomes differ in Prokaryotic and Eukaryotic cells (.5pts) Prokaryotic DNA is arranged in a circular “chromosome”. Eukaryotic DNA is arranged in linear, true chromosomes -7- 4. Where else in a cell can DNA be found and how is it hypothesized that it got there? (1pt) Mitochondria and chloroplasts. Hypothesized that they were once independent entities existing on their own, but through endosymbosis, they became part of the greater cell as we know it today 5. Briefly describe the function of the following: (1pts) a. Golgi Apparatus- works with the ER to “receive” and “ship” vesicles. Modifies products from the ER b. Ribosome- carry out protein synthesis. Are present in free and bound state. c. Smooth Endoplasmic Reticulum- engages in cellular metabolism. Synthesize lipids, steroids, oils and phospholipids. Also stores calcium ions. d. Mitochondria- carry out cellular respiration, converting chemical energy to sugars and ATP. e. Lysosome- Digest things within the cell. -8- 6. How do fibers in the cytoskeleton differ from one another? (.5pt) The cytoskeleton contains microfilament, intermediate filament and microtubule fibers. Microfilament fibers are rod-like fibers made of actin arranged in a double twisted chain. Intermediate filament fibers are made of various fibrous proteins and are ropelike in structure Microtubule fibers are straight, hollow tubes consisting of tubulins. 7. Explain the different roles that the three types of junctions perform and where they may be found in the body (1pt). The three types of junctions are Gap, Tight and Anchoring. Gap junctions are channels that allow small molecules through protein lined pores between neighboring cells. Tight junctions occur when the membrane of neighboring cells are pressed tightly together forming a tight seal that prevents any leakage. Anchoring junctions fasten cells into sheets and anchor the sheets in the cytoplasm. -9- 8. What structures are found in plant cells, but not animal cells? (.5 pt) Plants have a cell wall, vacuoles and chloroplasts 9.Label each organelle (1pt) Rough endoplasmic reticulum Smooth endoplasmic reticulum Nucleus Flagellum Lysosome Centriole Ribosomes Golgi apparatus Peroxisome Plasma membrane Mitochondrion - 10 - 10. Explain how the hydrophobic properties of lipids create a membrane that is semipermeable (.5 pt). The “head” is hydrophilic and the tail is hydrophobic. The hydrophilic head is exposed to the water and the hydrophobic portion is protected inside the membrane. This arrangement allows water and non-polar molecules to easily pass through the hydrophobic interior of the membrane, but polar molecules must be assisted through 11. Imaging you discovered a new type of cell unknown to science. What features would you look for to determine if the cell was prokaryotic or eukaryotic? (.5 pt) Membrane bound nucleus, DNA arrangement, the overall size of the cell, if the organelles were bounded by membranes, and how the cell reproduced . 12. The cells that produce hair contain a lot of ________, while the cells that produce the oils that coat the hair contain a lot of ________ (.5 pt). A) smooth endoplasmic reticulum . . . lysosomes B) rough endoplasmic reticulum . . . smooth endoplasmic reticulum C) smooth endoplasmic reticulum . . . rough endoplasmic reticulum D) microbodies . . . lysosomes E) nuclei . . . chromatin - 11 - 13. A drug that interferes with microtubule formation is likely to completely disrupt (.5pt) A) the production of ribosomes. B) the amoeboid motion of a cell. C) the function of lysosomes. D) contraction of muscle cells. E) the movements of sperm cells. 14. A child dies following a series of chronic bacterial infections. At the autopsy, the physicians are startled to see that the child's white blood cells are loaded with vacuoles containing intact bacteria. Which of the following explanations could account for this finding? (.5 pt) A) A defect in the Golgi apparatus prevented the cells from processing and excreting the bacteria. B) A defect in the rough endoplasmic reticulum prevented the synthesis of the antibodies (defensive proteins) that would have inactivated the bacteria. C) A defect in the cell walls of the white blood cells permitted bacteria to enter the cells. D) A defect in the lysosomes of the white blood cells prevented the cells from destroying engulfed bacteria. E) A defect in the surface receptors of the white blood cells permitted bacteria to enter the cells. - 12 -