Download MODELING THE CELL RECOGNITION PROCESS

 MODELING
THE
CELL RECOGNITION PROCESS
PhD – Diploma – Bachelor student projects
The recognition process is used by the cell to learn about its environment and is necessary for the viability and motility of singe cells but also tissues. The process is onset by the formation of ligand‐receptor bonds that form adhesion clusters. In the later stages, controlled by active regulation, the cytoskeletal network binds to the adhesion domains forming a matured focal adhesion point. Application of external force onto an adhesion domain results in its growth and stiffening of the cytoskeleton. The understanding of this process is obtained by modeling various components that affect the cell recognition process at different length and time scales Projects involving a variety of theoretical and simulation techniques are available. Experiments are performed in collaboration with CINAM, Marseille, France. Requirements: Experimental and theoretical studying of a cell model consisting of a receptor carrying vesicle adhering to a functionalized flat substrate. Excellent students interested in postgraduate studies. Capability to communicate in English. Contact: Prof. Ana‐Sunčana Smith [email protected]‐erlangen.de Phone: +4991318520842 Nägelsbachstrasse 49b, 91052 Erlangen Institute for Theoretical Physics I