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BIOL 1301 Module 3 - Metabolism – Learning Outcomes 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. Chapters: 6-8 Describe metabolic pathways and contrast catabolic and anabolic metabolic pathways. Distinguish between kinetic and potential energy and relate these to thermal and chemical energy. Describe in basic terms the consequences of the first and second law of thermodynamics. Relate the concept of change in free energy to spontaneity and endergonic and exergonic reactions. Summarize the ATP cycle and explain how hydrolysis of ATP can perform the three types of cellular work. Explain how enzymes affect the activation energy, change in free energy, and spontaneity of a process. Relate enzyme structure to substrate specificity, induced fit model, and mechanism of a lowering the activation energy. Describe factors that affect enzyme activity (local conditions, inhibitors, allosteric regulation) and relate them to regulation of metabolic processes. Illustrate the interplay of cellular respiration and photosynthesis in plants and relate this to energy flow through autotrophs and heterotrophs at the ecosystem level. Write the summary equation for cellular respiration AND photosynthesis and identify reactants and products that are oxidized or reduced. List three stages of cellular respiration, location of each stage in the eukaryotic cell, and describe the sequence of compounds through which electrons flow. List two stages of photosynthesis, location of each stage in the chloroplast, and summarize the cooperation between the stages. Describe general changes in the carbon skeleton during glycolysis, pyruvate oxidation and citric acid cycle. Explain how the electron transport chain creates a proton gradient and couples chemiosmosis to the endergonic production of ATP by ATP synthase. Differentiate between substrate level and oxidative phosphorylation and the contribution of each to ATP production by cellular respiration. Explain how fermentation regenerates NAD+ and its importance for continued ATP production in an anaerobic environment. Differentiate between fermentation, aerobic respiration, and anaerobic respiration. Recall that food molecules other than glucose are used as fuel for cellular respiration. Describe the absorption spectra of the main photosynthetic pigments relate this to the rate of photosynthesis stimulated by specific wavelengths of light. List the components of a photosystem and explain the function of each. Summarize the linear flow of electrons through PSII and PSI and summarize the ATP and NADPH yield. Describe the three phases of the Calvin cycle and specifically the reactions catalyzed by Rubisco.