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Review: genes chromosomes DNA location of genetic material Dec 21:49 PM Changes in Genetic Material your chromosomes are made up of genes which are considered your genetic material sometimes a cell's genetic information can change which will result in a mutation mutations can often result in problems for the organism involved because it results in a change in DNA structure there can however be good mutations Dec 21:50 PM 1 cartoon mutations are different then real life mutation not a real mutation mutations are changes in the order of the parts of a gene real mutations are caused by mutagens Dec 22:00 PM a mutagen is a substance or factor that causes a mutation there are usually two types of mutagen (a) Nature excessive sunlight (ultraviolet radiation can cause mutation in skin cells (skin cancer) exposure to natural elements such as lead or mercury have been shown to cause mutations Dec 22:09 PM 2 (b) Human Activity: exposure to cigarette smoke, cleaning products, and industrial waste can cause mutations the drug thalidomide was given to pregnant women in the 1950's and resulted in children born with missing limbs radiation from nuclear technology can also l ead to the development of cancerous tumors Dec 22:20 PM Skin cancer caused by excessive sunlight (Natural causes) Dec 22:25 PM 3 Mutation caused by thalidomide (human caused mutation) Dec 22:26 PM Positive and Negative Mutations Examples of positive mutation: some individuals carry a mutated gene which allows them to resist the HIV virus some plants have developed resistance to bacteria and fungal infections Examples of negative mutation: sickle cell anemia changes the shape of red blood cells so that they do not carry adequate amounts of oxygen cystic fibrosis is a genetic disease causing a build up of mucus in the lungs and respiratory system Dec 22:47 PM 4 Readings: Pages 122 130 Questions: Page 131: #'s 3,4,5,7,10,12,13,15 Thalidomide Effects: Dec 22:53 PM Other Mutation Examples: Tree Man: Girl With Two Faces: Genetic Mutations: Dec 108:47 AM 5