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MEDIA RELEASE For more information Newsroom Businesswire Australia and New Zealand [email protected] 28-Aug-2014 9:20 AM Topic: Health NuGEN Introduces Target Enrichment Technology for Comprehensive Detection of Gene Fusion Events in Oncology Research and Clinical Testing ~Most Complete NGS Target Enrichment Solution for the Detection of Gene Fusion Events Enabled in a Simple and Rapid Workflow~ SAN CARLOS, Calif.--(BUSINESS WIRE)--NuGEN Technologies, Inc., a market leader in the development of solutions for Next Generation Sequencing (NGS) applications, has announced the release of a novel targeted enrichment method that, in a single assay, will detect all possible fusion events involving 446 cancer fusion genes as curated by the Wellcome Trust Sanger Institute's Catalog of Somatic Mutations in Cancer (COSMIC). The proprietary NuGEN technology uses a unique single primer strategy that requires only one partner exon to be targeted, thereby enabling not only detection of known fusion events but also discovery of novel gene fusions and alternative splice forms. “Screening samples for a broad range of gene fusions has been a costly and time consuming process until now” NuGEN's proprietary Single Primer Enrichment Technology (SPET) is the core technology that delivers a highly sensitive method for detection of low abundance gene fusion transcripts with as little as 10 ng of total RNA derived from either fresh or formalin-fixed paraffin-embedded tissues. The easy, cost-effective assay employs a single day, rapid workflow. “Screening samples for a broad range of gene fusions has been a costly and time consuming process until now,” commented Doug Amorese, VP of R&D at NuGEN. “The SPET technology for targeted RNA sequencing enables NGS analysis to identify any fusion event in the targeted gene set and will be an important approach both in basic research and the development of RNA-Seq based cancer diagnostic and prognostic tests.” The Ovation Fusion Panel Target Enrichment System queries 5769 exons and is available with 8, 32 and 96 barcodes for efficient library generation and cost effective sequencing analysis. In addition, customized gene fusion panels using the same technology can also be made to specific user requirements. “We are actively working with partners who are currently using the standard Ovation Fusion Panel Target Enrichment System in clinical research programs and anticipate moving forward with custom designed fusion panels for use in clinical testing in the future,” said Joe Don Heath, NuGEN's Vice President of Diagnostic Market Development. NuGEN offers custom design services for target enrichment products with a three week turnaround from design to delivery and has an active diagnostic partner program for the supply of sample preparation technology. About NuGEN NuGEN Technologies is a San Carlos, CA company focused on innovative solutions for RNA and DNA that enable life scientists to do more with less. With reagent solutions that are quick, easy to use, and amenable to automation, NuGEN empowers researchers and clinicians to prepare genomic samples of any size, from almost any source, regardless of the intended application or technology platform. For more information please visit www.nugen.com. Ovation and NuGEN are registered trademarks of NuGEN Technologies, Inc. Contacts NuGEN Technologies, Inc. Carol Short, 650-590-3002 [email protected] About Businesswire Tens of thousands of communications and organisations around the world trust Business Wire to issue their press releases, multimedia and regulatory filings to news media, digital platforms, regulatory authorities and industry influencers. With thousands of distribution and targeting options that reach 162 countries in 50+ languages and 193 industry trade categories, Business Wire gives you access to the world's most powerful press release network. Built on our patented simultaneous and secure NX network and augmented with partnerships with international and national news agencies, Business Wire is a valued and trusted source for breaking news by reporters, investors and consumers. Founded in 1961, Business Wire has 32 bureaus around the globe and is a fully owned subsidiary of Berkshire Hathaway, a Fortune 5 company. On Twitter: businesswire On LinkedIn: http://www.linkedin.com/company/business-wire More from Business Wire Australia and New Zealand Get the latest media releases, subscribe to release alerts, and download print and web ready media files at: http://newsboost.com/newsroom/businesswire