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Doctoral College Metabolic & Cardiovascular Disease Cell death and authophagy in plant life GUEST LECTURE by Peter Bozhkov, PhD Department of Plant Biology & Forest Genetics, Uppsala BioCenter, Swedish University of Agricultural Sciences & Linnean Center for Plant Biology, Uppsala / Sweden Monday, 21.05.2012, 17:00h SR 44.22, ZMB, KFUG (Humboldstrasse 48, 2nd floor) The talk will dwell on the following findings and paradigms Vacuolar cell death • Cell corpses play many important roles during plant development. • There is no apoptotic cell death in plants. • Spruce embryos: “Caenorhabditis elegans” in plant cell death research. • Metacaspases are ancestors of animal caspases with a key role in plant cell death. • Degradomes of caspases and metacaspases might overlap despite distinct substrate specificity of the two groups of enzymes. • Terminal differentiation triggers autophagy to dismantle cells during plant development. • Autophagy prolongs lifespan of plants. Necrotic cell death Morphological characterization of plant cell deaths Cell Death Diff. (2011) 18, 1241-46 A gradient of programmed cell death along apical-basal axis of Norway spruce embryo