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Name_________________________________________________Date_____________________Period_________ From DNA to Protein http://learn.genetics.utah.edu/content/begin/tour/ What is DNA? •DNA is a set of _____________________ that is used for ______________________________ ____________________________________________________ •DNA is in a twisted ladder shape called a _____________________________________ •The sides of the ladder are made of a ___________________________________backbone. •In DNA, _______ and __________ are always paired together and _______ and __________ are always paired together. •DNA is made of letters. The letters make _______________ made of _______ letters. •The DNA words make sentences called _____________________. What is a gene? •Genes are directions for making ___________________________. •There are about ___________________________ genes in human DNA. •There is a gene for ____________________________________ that is a protein used for carrying oxygen in red blood cells. If this gene is mutated, it can cause a disorder known as ______________________________________________. What is a chromosome? •There is about __________________________________ of DNA in each cell in your body. •The DNA is packaged into units called _________________________________. •The shape of DNA called a _______________________________ helps package the DNA. Then the DNA is wrapped around some _____________________. These proteins are packaged together to form a _________________________. •Each human cell has ________ chromosomes, or __________ pairs (one set from each parent). •Males have _______ and _________ chromosomes. Females have ___________________ chromosomes. •Compared to humans’ 46 chromosomes, onions have _________, mosquitoes have _________, and carp have ________. What is a protein? •Our bodies are made of 100 trillion cells and each cell has ___________________ of proteins, each one with a different job. •One kind of protein is a __________________________ protein on nerve cells that transmit signals. _____________________________ proteins give cells their shape. http://www.wisc-online.com/objects/ViewObject.aspx?ID=ap1302 Protein synthesis •The cell gets a _______________________________ to make a specific _______________________. •A part of the DNA _______________________ where there is a ______________ to make the protein. _________________________________ move along the DNA to make _________________. This is called Transcription. (The DNA code is transcribed or copied into RNA.) •In RNA, _______ and ________ are paired together and __________ and __________ are paired together. •Many copies of the ___________________ are made and leave the ______________________. •The ______________________ binds with a ribosome where it is decoded. Since this is where the DNA language is changed to the protein language, this is called Translation. •The code on the m-RNA is read _______ bases at a time. This is called a triplet code or __________________. •Each codon stands for a different ___________________________________________. _____________________________________ has two ends. One has a binding site for a specific _____________________________________. The other is an ________________________ that binds with a specific codon. •The appropriate t-RNA attaches to and carries the activated amino acid to the ribosome. Anticodon bases pair with codon in order to bring specific amino acids to the correct place. Draw this happening below (page 9 of animation): (label the m-RNA, t-RNA, and ribosome.) •After another t-RNA brings a second amino acid, the two amino acids form a ______________________. •Another t-RNA brings another amino acid. The previous amino acids ________________________ and form more peptide bonds. •More and more amino acids are linked together to form a _____________________________________. •When the protein is made, ________________ is broken down and recycled.