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A segment of 11.2 Independent Assortment THINK ABOUT IT Nothing in life is certain. If a parent carries two different alleles for a certain gene, we can’t be sure which of those alleles will be inherited by one of the parent’s offspring. However, even if we can’t predict the exact future, we can do something almost as useful—we can figure out the odds. Independent Assortment How do alleles segregate when more than one gene is involved? The principle of independent assortment states that __________ for different traits can segregate ______________________ during the formation of ____________________. Mendel wondered if the segregation of one pair of alleles affects another pair. o Mendel performed an experiment that followed two _________________ ____________ as they passed from one generation to the next. o Because it involves two different genes, Mendel’s experiment is known as a twofactor, or _____________________, cross. Single-gene crosses are __________________ crosses. The Two-Factor Cross: F1 Mendel crossed true-breeding plants that produced only round yellow peas with plants that produced wrinkled green peas. The round yellow peas had the genotype RRYY, which is __________________________________________. The wrinkled green peas had the genotype rryy, which is __________________________________________. All of the F1 offspring produced round yellow peas. These results showed that the _______________ for yellow and round peas are _____________________ over the alleles for green and wrinkled peas. The Punnett square shows that the genotype of each F1 offspring was _________,_ ___________________________ for both seed shape and seed color. The two factor cross F2 Mendel then crossed the F1 plants to produce F2 offspring. o Mendel observed that 315 of the F2 seeds were ___________ & ___________, while another 32 seeds were wrinkled and green —the two ___________________________________. But 209 seeds had __________________________ of phenotypes, and therefore combinations of ___________________, that were _______ found in either parent. The alleles for seed shape ______________________________________ of those for seed color. Genes that segregate independently—such as the genes for seed shape and seed color in pea plants—___________________________________ each other’s inheritance. Mendel’s experimental results were very close to the _______________ ratio that the Punnett square shown predicts. Mendel had discovered the principle of _____________________________________. The principle of independent assortment states: that _________________ for different traits can __________________________________________ during gamete formation. A Summary of Mendel’s Principles What did Mendel contribute to our understanding of genetics? Mendel’s principles of heredity, observed through patterns of inheritance, form the basis of modern genetics. The inheritance of biological characteristics is determined by ______________________ called _____________, which are passed from parents to offspring. Where two or more forms (_______________) of the gene for a single trait exist, some forms of the gene may be _________________ and others may be ________________. In most sexually reproducing organisms, each adult has ______ copies of each gene—one from each parent. These genes segregate from each other when _______________________________________. Alleles for different genes usually ________________________ of each other. At the beginning of the 1900s, American geneticist Thomas Hunt Morgan decided to use the common _______________________ as a model organism in his genetics experiments. The fruit fly was an ideal organism for genetics because it could produce plenty of offspring, and it did so quickly in the laboratory. Before long, Morgan and other biologists had tested every one of Mendel’s principles and learned that they applied not just to pea plants but to _________________________ as well. The basic principles of Mendelian genetics can be used to study the __________________________________________ and to calculate the _______________________ of certain traits appearing in the next generation.