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Genetic Deaths Among Droids Angela Maxwell ITEC 67432 May 2017 Objectives Understand the impact of Bectra on the Droid population. Create pedigree charts for male and female Droids. Predict probabilities of death for Droid offspring. 1. The Problem About Bectra “ Bectra is a fatal genetic disease impacting Droids. It is caused by a recessive gene. Individuals who inherit Bectra die in the larva stage. 2. The Counselor’s Role What do I do? The Job of the Genetic Counselor ◎Assess Droids to determine their offspring’s risk for inherited conditions. ◎Provide information and support to Droid families and healthcare professionals. 3. Droid Reproduction Litters and Probability Litters ◎One gene is passed from each parent. DROID GENE INHERITANCE Father 50% Mother 50% Probability ◎Droids have six offspring per Litter. OFFSPRING IN EACH DROID LITTER Female 50% Male 50% Reproductio n Review Choose the phrase that best completes the sentence. Droid parents each pass on _____ to their offspring and there are ____ offspring in a litter. ◎ One gene; six ◎ Two genes; three 4. Genes Chromosomes and Inheritance Chromosomes ◎Genes are carried on chromosomes. Genes ◎ Genes are Dominant (B) or Recessive (b) B b B b Inheritance ◎Watch how each parent contributes one gene to its offspring so that traits are determined by pairs of genes. Genes ◎ Offspring must inherit a recessive from each parent for the recessive trait to show up in the offspring. B b B b 5. Notations How to mark genes Pedigree Chart Parent male female Offspring decea sed decea sed Notations ◎Dominant genes are designated by a capital letter B. B Notations ◎Recessive genes are designated by a lowercase letter b. b b Gene Review Choose the diagram that best explains inheritance. B B b b BB Bb bB bb B b B b BB BB bb bb “ Droid larvae have a 25% chance of inheriting Bectra. 6. Review practice Use the Diagram to Answer the Question The most likely genetic structure of individual 4 is: ◎BB ◎bb Use the Diagram to Answer the Question The most likely genetic structure of the father of individual 6 is: ◎Bb ◎bb Use the Diagram to Answer the Question If individuals 6 and 7 are paired, what is the probability of death of each offspring ◎50% ◎25% Correct Back to Review Incorrect Back to Review References ◎ Bureau of Labor Statistics. https://www.bls.gov/ooh/healthcare/gene tic-counselors.htm ◎Gene Inheritance. Khan Academy. https://youtu.be/NR3779ef9yQ?t=3m17s Credits ◎ Presentation template by SlidesCarnival, adapted by Angela Maxwell SlidesCarnival icons are editable shapes. This means that you can: ● Resize them without losing quality. ● Change line color, width and style. Isn’t that nice? :) Examples: