Download The test will be a mixture of MCQs related to basic cell biology

The test will be a mixture of MCQs related to basic cell biology, biochemistry, immunology, virology,
and microbial pathogenesis.
Sample questions for MPhil Molecular Pathology and Genomics Entrance Test
1. Which of the following is not considered a barrier to entry of pathogens? a) skin b) mucous
membranes lining the respiratory, digestive, reproductive and urinary tracts c) Cytokines d)
tears, saliva and urine that physically flush out microbes e) Resident bacteria/normal flora that
inhabit the body.
2. Which of the following cells is not a lymphocyte? a) monocyte b) B cell c) T cell d) NK cell
3. Nitric oxide (NO), previously known as a poisonous gas, is released from endothelial cells (and
some neurons). It is a ligand involved in local cell signalling. What is the function of nitric oxide?
a) Excitation of skeletal muscles
b) Increases blood glucose
c) Increases heart rate
d) Local vasodilatation from endothelial cells
e) Vasoconstriction of blood vessels
4. Lysosomes are spherical or oval vesicles derived from the Golgi apparatus. They are membranebound organelles of varying sizes containing hydrolase enzymes capable of digesting most
biological molecules. What is the function of lysosomes?
a) They manufacture membrane phospholipids and make cholesterol and steroid hormones
b) They are involved in the synthesis of proteins which may be destined for insertion into
membranes, used in lysosomes or exported
c) They are involved in the concentration, modification and packaging of proteins produced in
the rough endoplasmic reticulum
d) They destroy aged cell organelles that are first engulfed by rough endoplasmic reticulum
e) They generate adenosine triphosphate
5. An accurate measure of an enzyme concentration can be obtained by measuring catalytic
activity, only when
a) substrate concentration is limiting
b) enzyme concentration equals substrate concentration
c) enzyme concentration exceeds substrate concentration
d) substrate concentration is saturating
e) product formation is slow
6. Which of the following has the cellular components arranged in order of increasing size?
a) amino acid < ribosome < protein < virus
b) protein < ribosome < virus < amino acid
c) amino acid < protein < ribosome < virus
d) protein < amino acid < virus
e) amino acid < protein < virus < ribosome
7. Viruses always have a (n) _________ core and a (n) ________ coat called a capsid.
a) amino acid, protein,
b) nucleic acid, protein,
c) nucleic acid, polysaccharide,
d) amino acid, nucleic acid,
e) nucleic acid, amino acid