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AN ACTIVE AUSTRALIAN SCIENCE 8 CURRICULUM MODULE AUS BS8 SU STRAND: MODULE I: CELLULAR BIOLOGY STUDENT’S NAME: TUTORIAL: TEACHER’S NAME: DATE: _______________________________________________________________________________________ AUS Biological Sciences 8: Science Understanding Strand Module 1: Key Conceptual Understandings x x Students know that cells are the tiny living units that make up an organism. Students compare and contrast the structure of a typical animal cell with the structure of a typical plant cell. x Students are aware that cells contain a cell nucleus (except red blood cells) and structures called organelles that have particular functions. x Students know that some organisms consist of one cell only (they are unicellular); while other organisms consist of many cells (they are multicellular). x Students are aware that all cells are formed from existing cells by cell division. x Students understand that in order for the body of an organism to continue to function, cellular replacement must occur, involving cell division to replace worn, damaged and dead cells. Are nerve cells in the human brain replaced? x Students know that cell division for growth and replacement is called mitosis. _______________________________________________________________________________________ An Introduction to Cell Theory Cell theory is as important in the study of Biology, as Atomic theory is important in the study of Chemistry. x Backward Reference: In the Biological Sciences 7 SU Strand Module 1, I introduced this Science Concept: “Biologists refer to an individual living thing as an organism.” x Science Concept: Modern cell theory includes these science ideas: (1) All organisms are made up of cells, (2) Cells are the structural and functional units of all organisms, (3) Cells come from pre-existing cells by cell division, (4) All cells have basically the same chemical composition, (5) Metabolic energy flows occur within cells, and (6) Cells contain hereditary information that is passed from cell to cell during cell division. x In your study of the Biological Sciences, you will come across some organisms that are difficult to classify. For example: Question: Are viruses alive? Answer: Viruses have both living and nonliving characteristics. x Forward Reference: In the Biological Sciences Sub Strand at Year Level 9, you will study science ideas (4) and (5); and in the Biological Sciences Sub Strand at Year Level 10, you will study science idea (6) of modern Cell Theory. ͺǣͳ̹ǤǤ ȋʹͲͳͳȌ ͳ x Backward Reference: In the Biological Sciences 7 SU Strand Module 1, I introduced this Science Concept: “Most biologists now subdivide living things into five (5) major kingdoms including the Monera, the Protista, the Fungi, the Plantae, and the Animalia.” The prokaryotic kingdom Monera includes the bacteria and the cyanobacteria. The protists, fungi, plants, and animals are all eukaryotes. You will study the differences between prokaryotes and eukaryotes later in this AUS Science 8 SU module. What are the similarities and differences between typical plant cells and typical animal cells? Generalised Structure of typical Plant and Animal Cells How are plant cells similar to animal cells? How are plant cells different from animal cells? A cell organelle is a membranebound structure or compartment in a cell that performs a special function. Prokaryotes were believed, until very recently, to have no organelles. Some prokaryotes have now been described as having organelles, e.g., carboxysome (a protein-shell compartment for carbon fixation in some bacteria); chlorosome (a light harvesting structure in green sulfur bacteria); magnetosome (found in magnetotactic bacteria), and thylakoid (in some cyanobacteria). Can you now identify the cell organelles contained in a typical plant cell but not in a typical animal cell? 1. Which two cell organelles are found in a typical plant cell but not in a typical animal cell? [2 marks] 2. What is the function of the mitochondria, i.e., what do mitochondria do? [3 marks] ͺǣͳ̹ǤǤ ȋʹͲͳͳȌ ʹ Functions of some Cell Organelles TABLE 1: Functions of listed Cell Organelles Cell Structure Cell wall Location Found in bacteria, fungi, and plant cells. Not found in animal cells. Cell membrane Found in all cells. Nucleus Found in all cells except prokaryotes. Found in all cells Cytoplasm Description Is rigid and strong. Is made of cellulose. Found inside cell wall in plant cells. Forms outer layer in animal cells. Holds nuclear DNA. Mitochondria Found in all cells except prokaryotes. Is a clear and viscous jellylike material (cytosol) Are bean-shaped. Contain m-DNA. Vacuoles Plant cells have a single, large vacuole. Animal cells have small vacuoles. Found in algae and green plant cells. Not found in animal cells. Are fluid-filled sacs. Largest organelle in plant cells. Contains cell sap in plants. Are green, oval shaped and contain chlorophyll. Chloroplasts Function Support and protection. Allows H2O, CO2, and O2 to diffuse in/out of cell. Support and protection. Controls movement of materials in/out of cell. Barrier between cell and its environment. Maintains homeostasis. Controls cell activities. Supports and protects cell organelles. Site of aerobic cellular respiration. Break down glucose sugar molecules to release energy (ATP). Store food, water, metabolic and toxic wastes. Plants need to store large amounts of food (glucose and starch). Use sunlight energy to make food (glucose) in green plants by the chemical process of photosynthesis. Source URL: http://www.schools.utah.gov/CURR/science/sciber00/7th/cells/sciber/orgtable.htm Respiration in Animals and Plants Respiration is a chemical reaction that occurs in both animal and plant cells. During respiration, the energy released from glucose and oxygen is used by the cells to keep them living. Glucose and oxygen react in the cells to produce carbon dioxide gas and water. The overall cellular reaction is called aerobic respiration as oxygen from the air is needed for the reaction to occur. The summary word equation for aerobic respiration can be shown as: Glucose sugar + Oxygen gas Carbon dioxide gas + Water + energy (ATP) 3. Can you now write a summary chemical symbol equation for aerobic respiration? [5 marks] ͺǣͳ̹ǤǤ ȋʹͲͳͳȌ ͵ x Forward Reference: Year 8 students, as you have to know how to write balanced chemical symbol equations in the Chemical Sciences Sub Strand at Year Levels 9, and 10; please do not worry too much if you are unable to correctly answer Questions 3 and 4. Photosynthesis in Plants Green plants use chlorophyll in their leaves to trap light energy. The energy is used to chemically combine carbon dioxide with water to make glucose. The glucose is used in plant respiration, or converted into starch and stored in leaves. The overall process is called photosynthesis. Oxygen gas is produced as a by-product. The summary word equation for photosynthesis can be shown as: Light energy Carbon dioxide gas + Water Glucose sugar + Oxygen gas Chlorophyll 4. Can you now write a summary chemical symbol equation for photosynthesis? [5 marks] The Green Sea Slug The green sea slug Elysia chlorotica obtains chloroplasts, (cellular organelles that allow green plant cells to carry out photosynthesis), from the algae it eats. It stores these chloroplasts in the cells that line its stomach. x Backward Reference: In the Biological Sciences 7 SU Strand Module 1, I introduced this Science Concept: “Most biologists now subdivide living things into five (5) major kingdoms including the Monera, the Protista, the Fungi, the Plantae, and the Animalia.” The prokaryotic kingdom Monera includes the bacteria and the cyanobacteria. The protists, fungi, plants, and animals are all eukaryotes. 5. Would you classify the green sea slug as a plant or as an animal? You must give at least two reasons to support your answer. To help you correctly answer Question 5, you could apply a “mini-key” to the five kingdoms of living things. [3 marks] ͺǣͳ̹ǤǤ ȋʹͲͳͳȌ Ͷ Two main Classes of Cells Cells are divided into two main classes on the basis of whether or not they contain a nucleus. Prokaryotic cells do not have a nucleus; eukaryotic cells have a nucleus in which the genetic material is separated from the cytoplasm. Prokaryotic cells are generally smaller and simpler than eukaryotic cells; and their genomes are less complex, and they usually do not contain membrane-bound organelles. x Science Concept: The major and significant differences between prokaryotic and eukaryotic cells are that eukaryotic cells have a nucleus and membrane-bound organelles, while prokaryotic cells never have a nucleus, and usually do not contain organelles. The DNA of a prokaryotic cell floats freely within the cell; whereas the nDNA of a eukaryotic cell is held within its nucleus. TABLE 2: Some primary Differences between Prokaryotes and Eukaryotes Prokaryotes Nucleus absent Meiosis absent 1 basic genome Mitochondria absent Chloroplasts absent Endoplasmic reticulum absent Vacuoles absent x x x x Eukaryotes Nucleus present Meiosis Chromosome number 2-600 Mitochondria present Chloroplasts may be present Endoplasmic reticulum present Vacuoles present Science Concept: Meiosis is a two-part cell division process of those organisms that sexually reproduce. Meiosis results in sex cells (or gametes) that contain half the number of chromosomes of the parent cell. Forward Reference: In the Biological Sciences Sub Strand at Year Level 10, you will study the concept of meiosis to a much greater depth of understanding. Science Concept: The genome is the entire set of genetic instructions found within a cell. The human genome contains 23 pairs of chromosomes, found in the cell nucleus, as well as the small mitochondrial DNA found in cell organelles known as mitochondria. Science Concept: The endoplasmic reticulum is a network of tube-like membranes within the cell cytoplasm, which have either: a smooth surface (smooth endoplasmic reticulum), or a rough surface containing ribosomes (rough endoplasmic reticulum). 6. Most biologists believe that eukaryotes evolved from prokaryotes. Eukaryotes contain mitochondria, prokaryotes do not. By what theoretical, evolutionary process did eukaryotic cells acquire mitochondria? [5 marks] ͺǣͳ̹ǤǤ ȋʹͲͳͳȌ ͷ x Backward Reference: On Page 1 of this AUS Biological Sciences 8 SU Strand Module 1, I stated this Cell Theory science concept: Number (3) “Cells come from pre-existing cells by cell division”. How do new cells come from pre-existing cells? The Cell Cycle x Science Concept: Living cells go through a series of stages known as the cell cycle. The cells grow, copy their chromosomes, and then divide to form new cells. Stages within the Cell Cycle: In the G0 stage, the cell is resting and not undergoing cell division. The G1 stage is the period prior to the synthesis of DNA. In the G1 stage, the cell increases in mass in preparation for cell division. The S stage is the period in which the chromosomes are replicated by DNA synthesis. The G2 stage is the period after DNA synthesis has occurred, but prior to the start of prophase. In the G2 stage, the cell makes proteins and continues to increase in mass. Source of Image URL: http://www2.le.ac.uk/departments/genetics/vgec/education/under18/topics/cellcycle-mitosis-meiosis x Science Concept: The cell cycle is the process by which a single-celled fertilized egg (or zygote), develops into a mature organism. Also, the cell cycle is the process by which hair, skin, blood cells, and some internal organs are replaced. x Science Concept: Mitosis is the process whereby a single cell divides resulting, normally, in two identical cells, each containing the same number of chromosomes and genetic content as that of the original cell. x The process of mitosis within the cell cycle is illustrated by the schematic diagram displayed on Page 7. x Science Concept: Prophase is the early stage of nuclear division during which chromosomes condense and become visible. Prophase is the initial stage of mitosis or meiosis in which chromosomes become visible and the cell spindles begin to form. x Science Concept: Cytokinesis is the division of the cytoplasm and the plasma membrane following the division of the nucleus resulting in two cells, each having its own nucleus and cytoplasm surrounded by a plasma membrane. ͺǣͳ̹ǤǤ ȋʹͲͳͳȌ A Schematic Diagram of Mitosis The following schematic diagram locates and illustrates the process of mitosis within the cell cycle. Source of Image URL: http://en.wikipedia.org/wiki/Mitosis x Science Concept: The M stage of the cell cycle includes the processes of mitosis and cytokinesis. 7. Why must DNA replication occur as an essential step in the cell cycle? [3 marks] If you badly scrape your hand, your skin cells undergo mitosis to make new skin cells to repair the abrasion. x Science Concept: Wound repair is a complex process in which the skin (or another organ-tissue) repairs itself after injury. The healing of most wounds occurs by the processes of regeneration and repair. In regeneration, the wound heals as the lost tissue is replaced by cells from adjacent healthy tissue. Mitosis occurs in these adjacent cells to replace the cells lost as a result of the injury. In the repair process, lost tissue is replaced with fibrous scar tissue. Source of Images: http://en.wikipedia.org/wiki/Wound_healing ͺǣͳ̹ǤǤ ȋʹͲͳͳȌ Extension and Challenge Questions Questions about Red Blood Cells 8. What is one advantage of red blood cells having no cell nucleus? [1 mark] 9. What is one disadvantage of red blood cells having no cell nucleus? [1 mark] Questions about Nerve cells in the Human Brain 10. Are nerve cells in the human brain replaced? [2 marks] Extra Online Resources You may like to access these extra URL’s to learn more about cellular biology? URL 1: http://micro.magnet.fsu.edu/cells/index.html URL 2: http://history.nasa.gov/CP-2156/contents.htm URL 3: http://www.cellsalive.com/cells/cell_model.htm URL 4: http://www.ncbi.nlm.nih.gov/About/primer/genetics_cell.html URL 5: http://www2.nau.edu/~gaud/bio372/class/readings/giard.htm URL 6: http://bugs.bio.usyd.edu.au/learning/resources/CAL/Microconcepts/index.html URL 7: http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter2/animation__mitosis_and_cytokinesis.html URL 8: http://highered.mcgraw-hill.com/sites/0072495855/student_view0/chapter2/animation__control_of_the_cell_cycle.html URL 9: http://www.wiley.com/college/boyer/0470003790/animations/cell_structure/cell_structure.htm ͺǣͳ̹ǤǤ ȋʹͲͳͳȌ ͺ What new science ideas have you now learned about cellular biology by studying this AUS BS8 SU Strand Module 1? List your newly learned key Science Concepts, as dot-points, in the textbox given below. _______________________________________________________________________________________ A Self-Check Summative Assessment Table Now complete this assessment table by adding the ‘self-check’ mark achieved for your answer to each focus question. Your teacher will provide his/her ‘model’ answer to each question, via ‘whole of class’ discussion. Total Mark Possible = 30 Mark Achieved = Percent (%) Score Achieved = ͺǣͳ̹ǤǤ ȋʹͲͳͳȌ ͻ