Download bomb squad and movie mania 2012

You have been given a special top-secret mission. Because of your extensive
knowledge of protein synthesis you have been summoned by the man himself,
Mr. Austin Powers, to serve on the bomb squad. You job is to gain revenge on
Dr. Evil, through the utilization of the universe’s most powerful stink bomb.
You will be labeling the parts of the cell or the parts of protein synthesis in the
parenthesis to help us figure out the mysterious ingredients. Use the following
words (some are used twice as indicated with a “x 2”):
DNA, nucleus x 2, tRNA x 2, mRNA, transcription, nuclear pore, codon x 2, anticodon, stop
codon, amino acid(s) x 2, protein, cytoplasm x2, ribosome, & translation
The bomb plans (______________________) have to be kept in a safe
(________________________) on an island. Because they could be lost and these PLANS, the
only copy known to exist, are too valuable to be lost. So instead of taking the plans from
the safe (_____________________) you send a messenger (__________________________) to
retrieve the bomb plans. You do not want to take any chances of being caught by the
enemy (Dr. Evil), so instead of having the messenger simply retrieve the plans you tell
the messenger to rewrite (____________________________) the plans in to a code
(_____________________________). Once the messenger is done he/she will slip out through
a secret tunnel in the safe (_________________________) and into the ocean
(_________________________). Once in the ocean (_________________) you will need to find
the underwater bomb making factory (______________). There you can decipher the code
(________________________). To do this you hire a translator (____________________________)
to read the code and figure out the right ingredients for the feared STINK BOMB. Every
3 pieces of the code (____________________) tell us a word (___________________________)
that leads us to the right ingredient (___________________________). Remembering that
many ingredients (___________________________) make up the bomb itself
(__________________). The translator (________________________) reads until the signal
comes to stop (______________________________). Your mission is done, you have served
well, and rest assured that Dr. Evil’s Lair will never smell the same again.
This activity is to help you understand protein synthesis. Our normal classroom has been converted into a cell. The lab table at the front of the room (my desk) has become the nucleus. The
nucleus will contain the DNA strands, mRNA (a member of your group) needs to come up to the nucleus to copy the DNA strand (in mRNA code of course – if the DNA is AGT the mRNA
would be UCA). mRNA must transcribe the DNA in the nucleus (the DNA must never leave the nucleus). The mRNA will now go back to his/her desk or lab table (a ribosome). On the
ribosome the group needs to split mRNA into groups of 3 nitrogen bases (codons). Then you need to translate the anticodon (3 nitrogen base groups of tRNA) (opposite of codons if the mRNA
is UCA then the tRNA anticodon is AGU). The tRNA anticodons will be hanging up around the class. Your groups must find the correct anticodon, flip over the card and find the word under
the card (the amino acid). A string of amino acids makes up a protein (a sentence). Your group must also figure out the real amino acid sequence using the table. In DNA the nitrogen base
sequence TAC means start (the beginning of your sentence) and ATT, ATC, and ACT means stop (or a period for your sentence). Extra Credit: name the movie your sentence comes from.
DNA code
mRNA code
tRNA code
Amino Acids
(use table
below)
Sentence
1. Why does mRNA have to go into the nucleus to get the information from the DNA?
Use the mRNA code to find the correct Amino
Acid
U
Phenylaline
Phenylaline
Leucine
Leucine
C
Serine
Serine
Serine
Serine
A
Tyrosine
Tyrosine
Stop
Stop
G
Cysteine
Cysteine
Stop
Tryptophan
U
C
A
G
C
Leucine
Leucine
Leucine
Leucine
Proline
Proline
Proline
Proline
Histidine
Histidine
Glutamine
Glutamine
Arginine
Arginine
Arginine
Arginine
U
C
A
G
A
Isoleucine
Isoleucine
Isoleucine
Methionine
Threonine
Threonine
Threonine
Threonine
Asparagine
Asparagine
Lysine
Lysine
Serine
Serine
Arginine
Arginine
U
C
A
G
G
Valine
Valine
Valine
Valine
Alanine
Alanine
Alanine
Alanine
Aspartic acid
Aspartic acid
Glutamic acid
Glutamic acid
Glycine
Glycine
Glycine
Glycine
U
C
A
G
2. What happens on ribosomes and where are ribosomes located in a cell?
U
3. What is the difference between RNA and DNA? (list 3 reasons)
4. What does a chain of amino acids make?
5. Specifically, what are the jobs of mRNA and tRNA?
6. What happens in transcription and translation?