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CHAPTER 11 Concept check questions (in figure legends) FIGURE 11.1 Concept check: Explain why the mouse in part (d) died. Answer: In this experiment, the type R bacteria had taken up genetic material from the heat-killed type S bacteria, which converted the type R bacteria into type S. This enabled them to proliferate within the mouse and kill it. FIGURE 11.2 Concept check: What was the purpose of adding RNase and protease to a DNA extract? Answer: RNase and protease were added to the DNA extract to rule out the possibility that small amounts of contaminating RNA or protein was responsible for converting the type R bacteria into type S. FIGURE 11.5 Concept check: Why were two different radioisotopes used? Answer: In this experiment 32P was used to label DNA and 35S was used to label protein. FIGURE 11.7 Concept check: Which of these components are not found in DNA? Answer: Ribose and uracil are not found in DNA. FIGURE 11.10 Concept check: Which components of a nucleotide form the backbone of a DNA strand? Answer: Deoxyribose and phosphate form the backbone of a DNA strand. FIGURE 11.11 Concept check: Why is modeling useful? Answer: Modeling is useful because it shows how molecules can fit together in a complicated three-dimensional structure. FIGURE 11.14 Concept check: What holds the DNA strands together? Answer: Hydrogen bonding between base pairs and base stacking holds the DNA strands together. FIGURE 11.15 Concept check: Describe the major and minor grooves. Answer: The major and minor grooves are the indentations where the bases make contact with water. The major groove is wider than the minor groove. FIGURE 11.16 Concept check: What are the structural differences between B DNA and Z DNA? Answer: B DNA is a right-handed helix and the backbone is helical, whereas Z DNA is a left-handed helix and the backbone appears to zigzag slightly. Z DNA has the bases tilted relative to the central axis, whereas they are perpendicular in B DNA. There are also minor differences in the number of bases pairs per turn. FIGURE 11.17 Concept check: What types of bonds hold nucleotides together in an RNA strand? Answer: Covalent bonds hold nucleotides together in an RNA strand. FIGURE 11.18 Concept check: What are the base-pairing rules in RNA? Answer: A bonds with U and G bonds with C.