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DIHYBRID CROSSES a cross involving two genes consisting of nonidentical alleles The same rules for monohybrid questions apply. The Law of Independent Assortment: if genes are located on separate chromosomes, they are inherited independently of each other Inheritance of one trait is not affected by the other Ex. Green pea, smooth coat Green pea, wrinkled coat See figure 1 pg. 150 and figure 2 pg. 151 The results of homozygous dihybrid crosses See figure 3 pg. 151 Four possible combinations for the gametes of the genotype YyRr See figure 4 pg. 152 F2 Generation Punnett square for a Dihybrid cross Probability: what is the likelihood a specific trait will by inherited in regards to both phenotype and genotype the number of ways a specific event can occur (total number of possible genetic outcomes) Rules: 1. past outcomes have no effect on the future outcomes 2. the probability of independent events occurring together is equal to the product of those effects occurring separately Read pgs. 150 – 154 Pg. 154 # 1-4 Pg. 156 # 2,3 Chapter Review Pg. 158 – 159 # 6 – 17 DIHYBRID CROSSES 1. A pea plant that is homozygous for yellow and wrinkled peas is crossed with a plant that is homozygous for green and round peas. Green and round peas are dominant. Determine the possible offspring which may result. 2. In horses, black is dependant upon a dominant gene (B), and chestnut upon its recessive allele (b). The trotting gait is due to a dominant gene (T), the pacing gait to its recessive allele (t). If a homozygous black pacer is mated to a homozygous chestnut trotter, what will be the appearance of the F1 generation? 3. If two horses of the F1 generation in #2 were mated, what kinds of offspring could be produced and in what proportions? 4. If an F1 male from problem #2 was mated to a homozygous female black pacer, what kinds of offspring could be produced and in what proportions? 5. In rabbits, black is due to a dominant gene (B), and brown to its recessive allele (b). Short hair is due to a dominant gene (L), and long hair to its recessive allele (l). In a cross between a homozygous black short-haired male and homozygous brown long-haired female, what would be the genotype and phenotype of the F1 and the F2 generations? 6. In guinea pigs, rough coat is due a dominant gene (R) and smooth to its recessive allele (r). Short hair is dependant upon a dominant gene (L), and long hair upon its recessive allele (l). Give the phenotype and genotype and the ratios for each of the following crosses: a. smooth long-haired x completely heterozygous b. homozygous rough long-haired x homozygous smooth shorthaired c. RrLL x RRLl 7. An anemic condition in humans called thalassemia is controlled by codominant alleles. Homozygotes for the defective allele, TmTm, have a severe anemia (thalassemia major), whereas heterozygotes, TmTn, have mild anemia (thalassemia minor). Normal individuals are homozygous TnTn. An independent gene in humans determines the presence or absence of pigmentation, with the allele A (normal pigmentation) completely dominant over the allele a (albino). Show what the genotypes and phenotypes would be in the P, F1, and F2 generations from the cross: TmTmAA x TnTnaa.