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Biology Activity – Secret Message Directions: 1. Copy the following DNA strand onto a sheet of paper (Turn the paper sideways to use it in the longest direction). If it is longer than one line, skip at least 6 lines and continue copying. Label this molecule Strand A. DNA strand: ACC GCT TTG ACA CCG GTG GAT AAG TTA CCA TCC ATG TTC ACG TTT TTA GCG TTG CCT GTA TCT CTG TAG AAA AGA (NOTE: THIS IS A SINGLE STRAND OF DNA. ONLY ONE OF THE BACKBONES) 2. Directly below the DNA strand, transcribe the RNA transcript from this DNA segment. Label this molecule Strand B. 3. Directly beneath the mRNA strand, translate the amino acid sequence from this mRNA strand. Use the amino acid chart handed out in class or in your book on page (H-172, A- 143). Label this molecule Strand C. 4. Below the amino acid sequence, use the following key to decode the secret message. Label this Secret Message. Letter of Alphabet A B C D E F G H I J Amino Acid Letter of Alphabet Phenylalanine Serine Tyrosine Cysteine Leucine Tryptophan Proline Histidine Arginine Glutamine K, V, Start of Word Methionine (start) Amino Acid L M N O P R S T U Isoleucine Threonine Asparagine Lysine Alanine Valine Aspartic acid Glycine Glutamic acid End of Word Stop codon (NOTE: Methionine is acting as a “wild card” amino acid for this secret message since there are not 26 amino acids available.) 5. When you decipher (figure out) the secret message, DO WHAT IT SAYS. This will be your answer to Question #1. Questions: 1. What is the answer to the secret message? 2. What would the DNA code be for the following word?: “supercalifragilisticexpialidocious” 3. What is the scientific term for the formation of Strand B? Strand C? 4. Where does the formation of Strand B occur? Strand C? 5. What role does each different type of RNA play in the formation of Strand C?