Download What is the correct term for twins that are born attached together?

NAME _____________________________
Chapter 14 -GENETIC DISORDERS TEST
(2 points each)
MATCHING:
Match the genetic disorder with its description.
________
Change in hemoglobin gene causes red blood cells to
change shape causing circulatory problems
________
Degenerative brain disorder caused by extra CAG repeats
in the gene code whose symptoms appear around middle age
which results in nursing home care and eventually death
________
Inability to distinguish between certain colors
(especially red and green)
_______
Mutation in a blood clotting protein so individuals can’t stop
bleeding if injured
_______
Mutation in gene that breaks down the amino acid phenylalanine
which accumulates in their brain and persons become retarded if
they eat foods containing phenylalanine.
_______
Mutation in muscle proteins that gradually weakens and
destroys muscle tissue
_______
Syndrome in which a person has an extra #21 chromosome
causing mental retardation and often heart defects
_______
Females with only one X chromosome (XO)
_______
Males with extra X chromosomes (XXy, XXXy, XXXXy)
_______
Defect protein that transports Cl- ions causing mucous to build up
in lungs and digestive organs
_______
Enzyme defect that causes lipids to build up in the brain;
Results in blindness, retardation, and death by age 5
_______
Defect in bone formation causing normal size head and torso
but short arms and legs
A. ACHONDROPLASIA
B. HUNTINGTON’s
C. COLORBLINDNESS
D. TAY-SACHS
E. HEMOPHILIA
F. SICKLE CELL DISEASE
G. CYSTIC FIBROSIS
H. PHENYLKETONURIA
I. TURNER’S
J. DOWN
K. KLINEFELTER’S
L. DUCHENNE MUSCULAR
DYSTROPHY
MATCHING:
Match the genetic disorder with its description.
________
Change in hemoglobin gene causes red blood cells to
change shape causing circulatory problems
________
Degenerative brain disorder caused by extra CAG repeats
in the gene code whose symptoms appear around middle age
which results in nursing home care and eventually death
________
Inability to distinguish between certain colors
(especially red and green)
_______
Mutation in a blood clotting protein so individuals can’t stop
bleeding if injured
_______
Mutation in gene that breaks down the amino acid phenylalanine
which accumulates in their brain and persons become retarded if
they eat foods containing phenylalanine.
_______
Mutation in muscle proteins that gradually weakens and
destroys muscle tissue
_______
Enzyme defect that causes lipids to build up in the brain;
Results in blindness, retardation, and death by age 5
_______
Defect in bone formation causing normal size head and torso
but short arms and legs
_______
Syndrome in which a person has an extra #21 chromosome
causing mental retardation and often heart defects
_______
Females with only one X chromosome (XO)
_______
Males with extra X chromosomes (XXy, XXXy, XXXXy)
_______
Defect protein that transports Cl- ions causing mucous to build up
in lungs and digestive organs
A. TAY-SACHS
B. ACHONDROPLASIA
C. HUNTINGTON’s
D. COLORBLINDNESS
E. HEMOPHILIA
F. CYSTIC FIBROSIS
G. DOWN SYNDROME
H. KLINEFELTER’S
I. TURNER’S
J. SICKLE CELL DISEASE
K. PHENYLKETONURIA
L. DUCHENNE MUSCULAR
DYSTROPHY
MATCHING:
Match the genetic disorder with its description.
________
Change in hemoglobin gene causes red blood cells to
change shape causing circulatory problems
________
Degenerative brain disorder caused by extra CAG repeats
in the gene code whose symptoms appear around middle age
which results in nursing home care and eventually death
________
Inability to distinguish between certain colors
(especially red and green)
_______
Mutation in a blood clotting protein so individuals can’t stop
bleeding if injured
_______
Mutation in gene that breaks down the amino acid phenylalanine
which accumulates in their brain and persons become retarded if
they eat foods containing phenylalanine.
_______
Defect protein that transports Cl- ions causing mucous to build up
in lungs and digestive organs
*
*
*
_______
*
*
*
*
*
*
*
*
Mutation in muscle proteins that gradually weakens and
destroys muscle tissue
_______
Enzyme defect that causes lipids to build up in the brain;
Results in blindness, retardation, and death by age 5
_______
Defect in bone formation causing normal size head and torso
but short arms and legs
_______
Syndrome in which a person has an extra #21 chromosome
causing mental retardation and often heart defects
_______
Females with only one X chromosome (XO)
_______
Males with extra X chromosomes (XXy, XXXy, XXXXy)
A.
B.
C.
D.
E.
F.
*
A.
B.
C.
D.
E.
F.
PHENYLKETONURIA
CYSTIC FIBROSIS
HUNTINGTON’s
COLORBLINDNESS
HEMOPHILIA
SICKLE CELL DISEASE
*
*
*
TURNER’S SYNDROME
DOWN SYNDROME
TAY-SACHS
KLINEFELTER’S
ACHONDROPLASIA
DUCHENNE MUSCULAR
DYSTROPHY
NAME _____________________________
Chapter 14 -GENETIC DISORDERS TEST
(2 points each)
MULTIPLE CHOICE:
Put the letter of the answer that best completes the statement on the blank at the left.
_______ In humans an XX genotype makes you a ___________________
A. male
B. female
C. mutant
D. carrier
_______ In humans an Xy genotype makes you a ____________________.
A. male
B. female
C. mutant
D. carrier
________
__________________ cell mutations happen in sperm or eggs and can be passed on to the
offspring.
A. body
B. somatic
C. germ
D. allele
________
__________________ cell mutations happen in body cells so they affect the organism itself,
but are NOT passed on to offspring.
A. gamete
B. somatic
C. germ
D. allele
________
____________________ mutations cause death, often before birth.
A. somatic cell
B. X-linked
C. germ cell
D. lethal
________
A gene that is carried on an X or Y chromosome is called ______________________.
A. sex influenced
B. sex linked
C. autosomal
D. lethal
________
The failure of homologous chromosomes to separate during meiosis is called ______________
A. nondisjunction
B. frameshift
C. crossing over
D. synapsis
________ A family record that shows how a trait is inherited
over several generations is called a _____________
A. karyotype
B. Punnett square
C. pedigree
D. periodic table
________ A person that has one copy of a recessive autosomal allele and does not express the trait but can
pass it on to his/her offspring is called a __________________.
A. mutant
B. carrier
C. hemophiliac
D. gene marker
________
_______________________ can be carriers for AUTOSOMAL RECESSIVE disorders.
A. Only males
B. Only females
C. Both males and females
________
_______________________ can be carriers for X-LINKED RECESSIVE disorders.
A. Only females
B. Only males
C. Both males and females
________
A human zygote with 3 copies of a chromosome would have 47 chromosomes instead of 46.
This condition is called ____________________.
A. monosomy
B. disomy
C. tetrads
D. trisomy
________
_____________________________ twins have identical DNA.
A. monozygotic
B. dizygotic
C. fraternal
D. trisomic
________
This picture of an organism’s chromosomes is called a
______________________
A. pedigree
B. Punnett square
C. karyotype
________
The chromosomes that DO NOT determine sex are called ____________________
A. sex chromosomes
B. autosomes
C. gene markers
D. pedigree partners
________
Which parent determines the sex of the baby?
A. father
B. mother
________
The dense region in the nucleus of female cells that forms when one of the X chromosomes is
randomly inactivated is called a _____________________ body.
A. autosomal
B. sex-linked
C. nucleolus
D. Barr
________
Turner’s syndrome is an example of a _____________________ disorder.
A. trisomy
B. monosomy
C. somatic cell mutation
________
X-linked recessive disorders show up more frequently in ____________________.
A. females
B. males
________
Sickle cell disease is found more frequently in __________________________ populations.
A. Jewish
B. Caucasion
C. African American
________
Tay-Sachs disease is found more frequently in_________________________ populations.
A. male
B. Caucasion
C. African American
D. Jewish
Which members of this family show the trait? (Circle all that apply)
A
B
C
D
E
F
Which members of this family are carriers for the trait?
(Circle all that apply)
A
B
C
D
E
F
Which member of this family is a MALE without the trait?
A
B
C
D
E
F
SHORT ANSWER:
If you had a baby born with Phenylketonuria, tell how you could keep it from becoming retarded.
________________________________________________________________________________
Explain why X-linked disorders show up more frequently in MALES.
_______________________________________________________________________
_______________________________________________________________________
What is the correct term for twins that are born attached together?
__________________________________________
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BONUS:
Which genetic disorder can be found in a pedigree showing the royal families in Europe?
__________________________________
What trait changes in female cats as a result of the production of Barr bodies.
_______________________________
Name the autosomal recessive disorder carried on chromosome #21 mentioned in your book, that is named
after a famous baseball player.
_______________________________________________
USE THE DISORDERS IN THE WORD BANK TO ANSWER THE FOLLOWING:
(You don’t need to use them all.)
ACHONDROPLASIA
TAY-SACHS
PHENYLKETONURIA (PKU)
HEMOPHILIA
DUCHENNE MUSCULAR
DYSTROPHY
HUNTINGTON’S
DOWN SYNDROME
TURNER’S SYNDROME
KLINEFELTER’S SYNDROME
CYSTIC FIBROSIS
COLORBLINDNESS
SICKLE CELL DISEASE
Name 2 Disorders caused by an X-LINKED RECESSIVE gene:
____________________________________
____________________________________
Name 2 Disorders caused by NON-DISJUNCTION
_____________________________________
_____________________________________
Name 2 disorders caused by an AUTOSOMAL RECESSIVE gene:
_____________________________________
_____________________________________
Name 1 disorder that is caused by an AUTOSOMAL DOMINANT gene:
_____________________________________
Name 1 disorder that is caused by an AUTOSOMAL CODOMINANT gene:
_____________________________________