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Active Lecture Questions Chapter 17 Adaptive Immunity: Specific Defenses of the Host Copyright © 2010 Pearson Education, Inc. The type of protection provided by the injection of diphtheria toxoid. a. b. c. d. e. innate resistance naturally acquired active immunity naturally acquired passive immunity artificially acquired active immunity artificially acquired passive immunity The type of protection provided by the injection of antirabies serum. a. b. c. d. e. innate resistance naturally acquired active immunity naturally acquired passive immunity artificially acquired active immunity artificially acquired passive immunity The type of protection resulting from recovery from an infection. a. b. c. d. e. innate resistance naturally acquired active immunity naturally acquired passive immunity artificially acquired active immunity artificially acquired passive immunity A newborn’s immunity to yellow fever. a. b. c. d. e. innate resistance naturally acquired active immunity naturally acquired passive immunity artificially acquired active immunity artificially acquired passive immunity Antibodies that protect the fetus and newborn. a. b. c. d. e. IgA IdD IgE IgG IgM The first antibodies synthesized; especially effective against microorganisms. a. b. c. d. e. IgA IdD IgE IgG IgM Antibodies that are bound to mast cells and involved in allergic reactions. a. b. c. d. e. IgA IdD IgE IgG IgM Put the following in the correct sequence to elicit an antibody response: (1) TH cell recognizes B cell; (2) APC contacts antigen; (3) antigen fragment goes to surface of APC; (4) TH recognizes antigen digest and MHC; (5) B cell proliferates. a. b. c. d. e. 1, 2, 3, 4, 5 5, 4, 3, 2, 1 3, 4, 5, 1, 2 2, 3, 4, 1, 5 4, 5, 3, 1, 2 A kidney-transplant patient experienced a cytotoxic rejection of his new kidney. Place the following in order for that rejection: (1) apoptosis occurs; (2) CD8+ T cell becomes CTL; (3) granzymes released; (4) MHC class I activates CD8+ T cell; (5) perforin released. a. b. c. d. e. 1, 2, 3, 4, 5 5, 4, 3, 2, 1 4, 2, 5, 3,1 3, 4, 5, 1, 2 2, 3, 4, 1, 5 Patients with Chédiak-Higashi syndrome suffer from various types of cancer. These patients are most likely lacking which of the following: a. b. c. d. e. TR cells TH1 cells B cells NK cells TH2 cells How many classes of antibodies are there? a. b. c. d. 2 3 5 6 A typical antibody monomer has a. Two identical light chains and two identical heavy chains b. Two different light chains and two different heavy chains c. Two identical light chains and two different heavy chains d. Two different light chains and two identical heavy chains The stem of the Y-shaped antibody monomer is called the a. b. c. d. Constant region Fc region Variable region Active region Antigens that provoke a highly specific immune response can also be called a. b. c. d. Epitopes Haptens Immunogens Immunoglobulins An antigen that requires a T helper cell for antibody production is called a a. b. c. d. T-regulatory antigen T-cytotoxic antigen T-independent antigen T-dependent antigen IgG antibodies inactivate microbes by blocking their attachment to host cells in the binding process known as a. b. c. d. Neutralization Agglutination Antibody-dependent cell-mediated cytotoxicity Opsonization Which class of antibodies accounts for about 80% of all antibodies in serum? a. b. c. d. IgG IgD IgM IgE Plasma cells are formed after the proliferation of which type of cell? a. b. c. d. B cell T cell Memory cell Monocyte When a baby is born with an infection, this would be indicated by the presence of which class of antibody? a. b. c. d. IgM IgG IgE IgD Maturation of the T cells takes place in the a. b. c. d. Bone marrow Liver Thymus Spleen T cells are classified by certain glycoproteins on their surface called a. b. c. d. Granzymes Endogenous antigens Clusters of differentiation Interleukins Cytotoxic T lymphocytes attach to the target cell and release a. b. c. d. Lysozymes Perforin Granzymes Lytic enzymes The relative amount of antibody in the serum is referred to as the a. b. c. d. B-cell count Differential count Antibody titer T-cell count A person who has had measles will develop a. b. c. d. Naturally acquired active immunity Naturally acquired passive immunity Artificially acquired active immunity Artificially acquired passive immunity What type of immunity is conveyed when exposed individuals are given antibodies by injection? a. b. c. d. Naturally acquired active immunity Naturally acquired passive immunity Artificially acquired active immunity Artificially acquired passive immunity