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The Neurological Examination Robin Meek, M.D. Introduction to the Medical Profession March 22, 2006 Objectives: 1. List and discuss the 3 essential questions to consider when assessing neurological function. 2. Describe the 6 components of the neurological exam. Three Key Questions 1. Is there evidence of nervous system disease or dysfunction? 2. Where is the problem located? 3. What is the nature of the problem? 1. Is there evidence of nervous system disease or dysfunction ? Focal – stroke Diffuse – multiple sclerosis Systemic –peripheral neuropathy 2. Where is the problem? CNS vs. PNS Tracts vs. neurons UMN vs. LMN Cortical vs. subcortical Peripheral vs. Central Peripheral - Muscle - Neuromuscular junction - Spinal or cranial nerves - Plexus - Nerve roots CNS - - Spinal cord Brainstem Cerebellum Cerebrum - Right vs. left Cortex vs. subcortical 3. What is the nature of the problem? PIT VET 3-D PIT VET 3 - D PIT - pressure - infection - toxic or metabolic VET - vascular - epilepsy - trauma 3-D - demyelinating - degenerative - developmental Six Components 1. Mental status 2. Cranial nerves 3. Motor 4. Sensory 5. Reflexes 6. Coordination Six Components 1. Mental status 2. Cranial nerves 3. Motor 4. Sensory 5. Reflexes 6.Coordination Mental Status Alertness or awareness Orientation Six Components 1. Mental status 2. Cranial nerves 3. Motor 4. Sensory 5. Reflexes 6.Coordination The Cranial Nerves I II III IV V VI Olfactory Optic Oculomotor Trochlear Trigeminal Abducens VII VIII IX X XI XII Facial Acoustic Glossopharyngeal Vagus Spinal accessory Hypoglossal Olfaction (CN I) Almost never tested Smell Coffee, mint, essence of orange Impaired olfaction: Inflammation (allergies or colds) Smoking Aging Anosmia CN II - Vision Three steps: 1.Visual fields by confrontation 2. Visual acuity testing – patient should wear their usual corrective lenses 3. Funduscopic examination –red reflex, optic disc, retinal vessels Pupillary Light Reflex (CN II,III) Check pupil symmetry Swinging penlight– pupils should remain equally constricted Anisocoria – one pupil is larger than the other - Normal variant - Sympathetic vs. parasympathetic Sympathetic – responsible for dilation - asymmetry greatest in the dark Parasympathetic – responsible for constriction - asymmetry greatest in the light IV Trochlear Downward and inward movement of the eye Innervates the superior oblique VI Abducens Lateral deviation of the eye Innervates the lateral rectus Nystagmus Experiment on your buddy! V Trigeminal Mixed nerve – somatic sensory and somatic motor Sensory nucleus – pons and medulla, becoming continuous with the posterior horn of the spinal cord Motor nucleus – confined to the pons Trigeminal - Sensory Three branches: opthalmic, maxillary, mandibular Sensory input from the face and mucus membranes (ocular, nasal, and oral) excluding the external ear and the posterior head, via the trigeminal ganglion Trigeminal - Motor Supplies the muscles of mastication (masseter, temporal, internal and external pterygoid) muscles and other minor pharyngeal muscles Trigeminal Examination 1. 2. 3. 4. Pinprick and fine touch sensation in forehead, cheek, and mandible bilaterally Corneal reflex Jaw movements and jaw reflex Palpation of jaw muscles for tone and strength with teeth clenched VII Facial Mixed nerve Motor – facial musculature except for levator palpebrae (CN III) Superior salivatory nucleus – submandibular and sublingual glands VII Facial Sensory Nucleus solitarius – taste from anterior 2/3 of the tongue ( sweet and salty) Sensory nucleus 5 – sensation from the external ear VII – Three Steps 1. Inspection at rest and with facial expression 2. Wrinkling the forehead – differentiates central from peripheral lesion 3. Identifying sweet and salty tastes on both sides of the tongue Try it out! VIII Acoustic Hearing - cochlear division Balance – vestibular division - seldom tested in basic neuro. exam VIII – Two Steps 1. 2. Assess hearing, covering opposite ear: whispered words rubbing your fingers ticking watch Rinne test – bone and air conduction IX Glossopharyngeal Mixed nerve Motor – pharynx Sensory – posterior portions of the eardrum and ear canal, the pharynx, and the posterior tongue (salty, sweet, sour, and bitter) X Vagus Mixed Motor – palate, pharynx, and larynx Sensory – pharynx and larynx Testing IX and X Listen to the patient’s voice – is it hoarse or does it have a nasal quality? Say “ah” – look at the soft palate and the pharynx. Gag reflex – stimulate both sides of the back of the throat and note the gag response (warn the patient) XI Spinal accessory Shoulder and neck movements Look for atrophy or fasiculations in the trapezius muscles, compare one side to the other Shrug shoulders Turn head against your hand XII Hypoglossal Somatic motor – muscles of the tongue Observe the tongue for muscle atrophy or fasiculations Ask patient to protrude tongue and move it from side to side – ? symmetry, deviation from the midline Your turn! Six Components 1. Mental status 2. Cranial nerves 3. Motor 4. Sensory 5. Reflexes 6.Coordination Motor Exam Body position – abnormal positions alert you to deficits such as paralysis Involuntary movements – tremors, tics, or fasiculations Muscle bulk – atrophic, symmetric or asymmetric? Especially shoulders, hands, thighs Tone and strength Muscle Strength Grade 5 - full strength Grade 4 - weak against resistance Grade 3 - movement against gravity Grade 2 – movement with gravity eliminated Grade 1 – minimal contraction Grade 0 – no contraction Muscle Tone flaccid – a decrease in tone normal – slight resistance to passive movement spastic – increased tone that varies, often worse at the extremes of the range rigid – resistance that persists throughout the range of motion and in both directions Lower Motor Neurons Corticospinal tract or pyramidal system – - mediates voluntary movements - crosses over at the junction of the brainstem and the spinal cord Reticulospinal or rubrospinal tracts – - extrapyramidal system - connects basal ganglia with the LMN - integrate motor activity and posture UMN vs. LMN UMN LMN Paralysis spastic flaccid Muscle atrophy no yes Fasiculations no yes Reflexes Hyper-reflexic Hypo-reflexic Babinski sign May be present Not present Lower extremity nerve roots Demonstration Symmetric weakness of the proximal muscles – myopathy or a muscle disorder Symmetric weakness of the distal muscles suggests a polyneuropathy or a disorder of the peripheral nerves Six Components 1. Mental status 2. Cranial nerves 3. Motor 4. Sensory 5. Reflexes 6.Coordination Sensory Examination 1. 2. 3. 4. 5. 6. Superficial pain and touch Temperature Deep pain or pressure Vibration Position Discriminative functions Ascending Tracts Lateral spinothalamic – superficial pain and temperature Posterior columns – vibration, deep pressure, position sense, point location, stereognosis, and two-point discrimination Spinocerebellar – proprioception Ventral spinothalamic – superficial touch and deep pressure Superficial pain – pinprick , “sharp or dull” Light touch – fingertips or wisp of cotton (Temperature – ice and warm water in test tubes) Deep pain – squeezing the calf or biceps muscle Vibration sense – vibrating tuning fork against bony prominences with patient’s eyes closed, “When does it stop?” Position sense – holding a distal joint of the fingers and toes and moving up or down Discriminative Function Reflects the ability of the sensory cortex to correlate, analyze, and interpret sensations Sterognosis – identify an object (coin) Two-point discrimination - find the distance where the patient no longer perceives two stimuli Graphesthesia – recognize numbers or letters drawn on skin Extinction – touch both sides of the body simultaneously with closed eyes Point location – with the patient’s eyes closed, touch an area on the body, withdraw the stimulus, and then ask the patient to point to the area touched Six Components 1. Mental status 2. Cranial nerves 3. Motor 4. Sensory 5. Reflexes 6.Coordination Reflexes Superficial reflexes: - abdominal reflex – contraction toward the stimulus - cremasteric reflex – elevation of the ipsilateral scrotum and testicle by touching the thigh Deep Tendon Reflexes 0 Absent 1+ Hyporeflexic 2+ Normal 3+ Hyperreflexic 4+ Clonus Eliciting Reflexes 1. 2. 3. 4. 5. 6. 7. Biceps (C5, C6) Brachioradialis (C5, C6) Triceps (C6, C7) Patellar (L2, L3, L4) Achilles (ankle – S1) Plantar (L5, S1) Clonus – indicates CNS disease Demonstration Babinski sign Six Components 1. Mental status 2. Cranial nerves 3. Motor 4. Sensory 5. Reflexes 6.Coordination Coordination Four areas that need to work together: 1. Motor system 2. Cerebellum – for rhythmic movement and steady posture 3. Vestibular system – for balance & for coordinating eye, head, and body movements 4.Sensory system – for position sense Coordination Rapid alternating movements Point to point movements Gait – walk down the hall, heel to toe, walk on toes, and then on heels Standing – Romberg test Pronator Drift Changes With Aging Motor system – move and react with less speed and agility, muscle mass decreases Benign essential tremor Vibration sense decreased or lost in feet or ankles Reflexes – gag, ankle reflexes decreased “Benign forgetfulness” Demo Six Components 1. Mental status 2. Cranial nerves 3. Motor 4. Sensory 5. Reflexes 6.Coordination