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Transcript
http://www.youtube.com/watch?v=PCVO9c9q4tE Autosomal Dominant Disorder: Inheritance of only one copy of the mutated gene is necessary to be affected by the Autosomal Dominant Disorder, Huntington’s Disease and others. Reproduction is then more dangerous because children have a 50% chance of inheriting the mutated gene if their parent has it. This is because the mutated gene is expressed in both dominant Homozygotes and Heterozygotes. Autosomal Recessive Disorder: Whereas, Autosomal Recessive Disorders require two mutated genes be inherited to be affected (most genetic disorders are recessive). Ex: Cystic Fibrosis, Sickle-Cell Anemia, and TaySachs Disease. All would be Homozygous Recessive for these disorders. Recessive disorders are usually inherited when both parents are “carrying” the mutated recessive gene (they are Heterozygotes). Most people do not know they are a CARRIER until they have a child with the disease. The value of studying Genetics is in understanding how we can predict the likelihood of inheriting particular traits. How to set up a Punnett Square: Dihybrid Crosses: The cross or mating between two organisms where two genes are studied are called a DIHYBRID cross. The genes are located on separate chromosomes, so the traits themselves are unrelated. GgWw X GgWw
