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Repro Intro CHAPTER 21 Reproductive System FUNCTIONS OF THE REPRODUCTIVE SYSTEM Accomplish reproduction – Creation of new life Manufacture hormones – – Females – estrogen and progesterone Males – testosterone FERTILIZATION Coitus- Intercourse Sperm production- Male’s contribution Ovum (egg)- Female’s contribution Fertilization (egg and sperm combine) occurs and results in a zygote, a fertilized egg. It takes place in the fallopian tube. FERTILIZATION DNA- All inherited traits are determined at fertilization with 50% from each parent. The child’s sex determined by the father. FEMALE REPRODUCTIVE SYSTEM Ovaries: Primary sex organ, releases ovum. Process is called ovulation. Fallopian tubes: Carries ovum to uterus Uterus: Hollow, muscular pear shaped organ. Cervix is the narrow neck of the uterus. Zygote implants and develops. FEMALE REPRODUCTIVE SYSTEM Menstruation is the breakdown of the endometrium (lining of the uterus) if the zygote does not implant or if fertilization does not occur. FEMALE REPRODUCTIVE SYSTEM, CONT. Vagina: Receives penis during intercourse and birth canal during delivery External female genitalia (vulva) includes labia and clitoris FEMALE REPRODUCTIVE SYSTEM, CONT. Breasts- Produce nourishment for baby after birth to ensure survival. FEMALE REPRODUCTIVE SYSTEM STRUCTURES MALE REPRODUCTIVE SYSTEM Testes: Primary sex organ for men Epididymis: Stores sperm until they mature Scrotum: Tissue sac that holds the testes and epididymis, contracts and expands to regulate temperature of testes for sperm production MALE REPRODUCTIVE SYSTEM, CONT. Vas deferens and seminal vesicles: Tubes that carry sperm MALE REPRODUCTIVE SYSTEM, CONT. Prostate gland: Size of a chestnut, contracts to close the urethra to stop urine and aid in expulsion of semen MALE REPRODUCTIVE SYSTEM, CONT. Semen: Mixture of sperm and fluids to aid ejaculation and impregnation Penis: External sex organ used to transfer semen to the female MALE REPRODUCTIVE SYSTEM Erection: Penis fills with blood to stiffen for insertion into vagina Ejaculation: Semen leaves penis via the urethra MALE REPRODUCTIVE SYSTEM STRUCTURES CONTRACEPTION Some Religious and ethnic groups prohibit Abstinence: Only method 100% effective Used as a reason for avoiding pregnancy CONTRACEPTION, CONT. Methods of contraception vary from drugs (birth control pills or injections), to mechanical methods (condoms, IUDs, diaphragm), to timing (rhythm method-coordinated with menstrual cycle) INFERTILITY When conception does not occur after trying for one year In vitro fertilization (IVF): Ovum fertilized outside of the body and transferred to the uterus EFFECTS OF AGING – FEMALE Decreased estrogen and progesterone production Narrowing of vaginal opening, loss of tissue elasticity and a decrease in vaginal secretions MENOPAUSE When monthly menstrual cycle comes to an end End of childbearing MENOPAUSE, CONT. Commonly occurs between 45 and 55 years of age Psychological changes include depression and irritability EFFECTS OF AGING – MALE Sexual response is slower Obtaining and maintaining an erection becomes more difficult Prostate gland size increases, testes decrease in size and sperm level decreases EFFECTS OF AGING – MALE, CONT. Testosterone level decreases DISORDERS – FEMALE REPRODUCTIVE SYSTEM Amenorrhea: Absence of a menstrual cycle DISORDERS – FEMALE, CONT. Premenstrual syndrome (PMS): A group of physical and emotional symptoms occurring one to two weeks prior to the start of menstruation. DISORDERS – FEMALE REPRODUCTIVE SYSTEM Menorrhagia: Excessive or prolonged menstrual bleeding Endometriosis: Uterus tissue outside of the uterus in the abdominal cavity Dysmenorrhea: Painful menstruation DISORDERS – FEMALE REPRODUCTIVE SYSTEM, CONT. Fibroid tumors: Non-cancerous growths in the wall of the uterus DISORDERS – FEMALE REPRODUCTIVE SYSTEM, CONT. Breast tumors: Second most common form of cancer in females after skin cancer Cervical cancer: Cancer of the neck of the uterus. INFECTIONS – FEMALE REPRODUCTIVE SYSTEM, CONT. Toxic shock syndrome: Potentially life-threatening staph infection Vaginal yeast infections: Typically occurs as a result of antibiotic use DISORDERS – MALE REPRODUCTIVE SYSTEM Epididymitis: Infection that causes pain and swelling of the groin and scrotum Benign Prostatic Hypertrophy (BPH)- caused by changes in hormone levels resulting in difficulty starting to urinate, a weak stream and nocturia. o Impotence/erectile dysfunction (ED): Inability to obtain, or maintain, an erection. Most causes are physical o Prostate cancer: Cancer of the prostate gland SEXUALLY TRANSMITTED INFECTIONS (STIS) Also known as venereal disease Passed during childbirth or during an exchange of body fluids Many have no symptoms STIS, CONT. Prevention includes the use of barriers and avoidance of contact Condom is the only contraceptive that protects against STIs. STIS, CONT. Chlamydia: Most commonly transmitted and presents with no symptoms in most people Genital warts or human papillomavirus (HPV): Most commonly sexually transmitted virus. Immunization available for males and females. STIS, CONT. Gonorrhea: Bacterial, painful urination and pus discharge STIS, CONT. Genital herpes: Virus, causes lesions (sores) on the genitalia STIS, CONT. Syphilis: Potentially life threatening bacteria infection STIS, CONT. Trichomoniasis vaginitis: Protozoan infection that causes itching and burning of the urethra and vagina HUMAN GROWTH AND DEVELOPMENT Zygote: United sperm and ovum. 0-2 weeks (from conception) Embryo: Cell growth. 2-10 weeks Fetus: Development of organs. 10 weeks to birth. HUMAN GROWTH AND DEVELOPMENT Infancy: Most dramatic changes of growth Toddler- Walking begins Preschool- Learning about self and world HUMAN GROWTH AND DEVELOPMENT School-age- Formal education occurs Adolescence- Beginning of puberty HUMAN GROWTH AND DEVELOPMENT Early adulthood- Career, leaving to start a home, child rearing HUMAN GROWTH AND DEVELOPMENT Middle adulthood- Child rearing, empty nest Older adulthood: Many emotional and social adjustments GENETICS TERMS Genetics: Study of how genes are transmitted from parents to offspring Mutations: Human Change in a gene or chromosome genome: Mapping of genes and chromosomes on human DNA GENETICS TERMS, CONT. Genotype: The two genes that represent a characteristic such as eye or hair color Phenotype: What the characteristic looks like (dark, blonde or red hair) GENETICS TERMS, CONT. Humans have 23 pairs of chromosomes. Number 23 indicates gender. XX means female XY means male GENE MUTATIONS Occurs randomly in any cell occasionally Somatic cell mutation-Change in body cells such as skin cells Chromosomal mutation- Change in the number of chromosomes Mutagenic agent – speeds up the rate of mutation; ex: radiation (x-rays, UV), chemicals LETHAL GENES Inherited mutations are generally negative happenings to the individual An inherited gene that results in death is a lethal gene The time at which lethal genes exert their deadly influence varies from zygote stage to an adult LETHAL GENES Each person may carry 2-3 different recessive lethal genes Two similar recessive genes must be present in an individual for the gene to be expressed Common ancestry are more likely to share many genes which increases the chances of stillbirths and genetic disorders HUMAN GENETIC DISORDERS Can be genetic (from the parent’s genes) or congenital (during development) HUMAN GENETIC DISORDERS, CONT. Phenylketonuria (PKU): Caused by an enzyme deficiency where the body cannot break down the amino acid alanine. The build-up causes mental retardation due to lack of brain development HUMAN GENETIC DISORDERS, CONT. Sickle cell anemia: Common in people of African descent where a defect in the hemoglobin molecule changes the RBC to a crescent shape. This causes a clumping of RBCs and a decrease in oxygen being carried. HUMAN GENETIC DISORDERS, CONT. Tay-Sachs disease: An enzyme deficiency causes a build-up of lipids in the brain causing death a few years after birth. • Common in people of Central/Eastern European Jewish descent HUMAN GENETIC DISORDERS, CONT. Duchenne’s Muscular Dystrophy: A disease where muscles lose protein and are replaced by fat and connective tissue resulting in death by age 20. HUMAN GENETIC DISORDERS, CONT. Huntington’s disease: The central nervous system breaks down resulting in abnormal movements and mental deterioration HUMAN GENETIC DISORDERS Cystic fibrosis: Thick mucus is excreted that blocks the respiratory passages; also can cause bronchitis and pneumonia HUMAN GENETIC DISORDERS, CONT. Thalassemia: A form of anemia that occurs in people of Mediterranean descent that results in congestive heart disease. HUMAN GENETIC DISORDERS, CONT. Hemophilia: A sex linked (occurs on the X chromosome) disorder that results in the person’s blood being unable to clot HUMAN GENETIC DISORDERS, CONT. Chromosomal aberrations: Missing or extra chromosome Turner’s Syndrome: Missing Y chromosome (XO) results in abnormal female sexual development Kleinfelter’s Syndrome: Extra X chromosome (XXY) Males are infertile, with less muscles, less facial hair and broader hips HUMAN GENETIC DISORDERS, CONT. Trisomy 21: Down’s syndrome, an extra chromosome at #21 resulting in mental retardation and changes in physical formation ADVANCES IN GENETICS Genetic engineering: Manipulation of genes A gene is isolated, modified and reintroduced to change a characteristic. Used for insulin, human growth hormone and interferon (interferes with virus replication) ADVANCES IN GENETICS, CONT. Gene therapy: Correcting defective genes. Done 3 ways A normal gene is inserted A normal gene is swapped for an abnormal gene An abnormal gene is changed through reverse mutation GENETIC COUNSELOR Genetic counseling is the process of helping people understand and adapt to the medical, psychological and familial implications of genetic contributions to disease. This process integrates: -Interpretation of family and medical histories to assess the chance of disease occurrence or recurrence. GENETIC COUNSELOR -Education about inheritance, testing, management, prevention, resources and research. -Counseling to promote informed choices and adaptation to the risk or condition. In order to become a Certified Genetic Counselor (CGC©), one must obtain a Master’s degree in Genetic Counseling GENETIC COUNSELOR The median annual wage for genetic counselor is $67,500. Depending on location, experience and other factors, salaries range from $44,000 to $100,000 Employment of genetic counselors is projected to grow 41 percent from 2012 to 2022, much faster than the average for all occupations. NURSE MIDWIFE Diagnose and coordinate all aspects of the birthing process, either independently or as part of a healthcare team. May provide wellwoman gynecological care. Must have specialized, graduate nursing education. NURSE MIDWIFE Nurse midwives must earn at least a master’s degree in one of the APRN roles. They must also be licensed in their state and pass a national certification exam. NURSE MIDWIFE Median wages for nurse midwives is $97,000. Wages will range from $66,000 to $129,000. Employment of nurse midwives is expected to grow 31 percent from 2012 to 2022, much faster than the average for all occupations. Growth will occur primarily because of the effects of healthcare legislation and an increased emphasis on preventative care. CYTOGENETIC TECHNOLOGIST Performs microscopic analysis for cytogenetic studies on biological specimens from cell cultures. Studies include hematological disorders, fertility problems, chromosome analyses for prenatal diagnosis, and congenital birth defects. CYTOGENETIC TECHNOLOGIST Responsibilities include slide preparation, photomicroscopy, microscopy, computer image analysis, karyotyping, culturing and harvesting procedures, and result reporting. Requires a bachelor's degree and a certificate in cytogenetics or clinical genetics. CYTOGENETIC TECHNOLOGIST The median annual wage for cytogenetic laboratory technologists was $57,580 in May 2012. The lowest 10 percent earned less than $39,580, and the highest 10 percent earned more than $78,900. Employment of cytogenetic technologists and technicians is projected to grow 22 percent from 2012 to 2022, much faster than the average for all occupations. THE END