Download Proteins - Forest Hills School District

Document related concepts

Gaseous signaling molecules wikipedia , lookup

Glycolysis wikipedia , lookup

Protein wikipedia , lookup

Endomembrane system wikipedia , lookup

Deoxyribozyme wikipedia , lookup

Expanded genetic code wikipedia , lookup

Genetic code wikipedia , lookup

Cyclol wikipedia , lookup

Amino acid synthesis wikipedia , lookup

Vectors in gene therapy wikipedia , lookup

Protein adsorption wikipedia , lookup

Enzyme wikipedia , lookup

Proteolysis wikipedia , lookup

Cell-penetrating peptide wikipedia , lookup

Photosynthetic reaction centre wikipedia , lookup

Evolution of metal ions in biological systems wikipedia , lookup

Nucleic acid analogue wikipedia , lookup

List of types of proteins wikipedia , lookup

Biochemistry wikipedia , lookup

Transcript
Intro to Cell Biology
Review
Name an atom found in DNA but
not carbohydrates and lipids
Nitrogen and phosphorus
Kind of chemical reaction used to join
subunits when making polysaccharides,
proteins, and nucleic acids
Dehydration synthesis
http://www.animationlibrary.co
Which of the characteristics
of living things is this frog
demonstrating?
Grow and develop
Scientists are worried the Bird Flu virus will mutate
and become able to spread from person to person
causing a worldwide epidemic.
Which of the characteristics of living things is this an
example of?
Evolution; change over time
What ratio of carbon, hydrogen, and
oxygen atoms is seen in carbohydrates?
1:2:1; 1 carbon:2 hydrogen:1 oxygen
What is the chemical formula for
water?
H2O
Which of the following characteristics
of living things explains why birds fly
south for the winter?
A.
B.
C.
D.
Maintain internal balance
Made up of cells
Based on a universal genetic code
Respond to their environment
D. Living things respond to their environment
http://www.biologycorner.com/bio3/images/bloodcells3D.jpg
Looking at a drop of blood
under the microscope you
see this. Which of the
characteristics of living
things is this an example
of?
Made of cells
Which of the characteristics of
living things are these examples
of?
Reproduce
Family image from: http://babyhearing.org/Parenet2Parent/index.asp
Planaria animation: http://www.t3.rim.or.jp/~hylas/planaria/title.htm
Which of these molecules is an amino acid ?
Look closely! They all are.
Look for the groups
Amino, carboxyl, R
http://www.bcps.org/offices/lis/models/life/images/grow.JPG
Which of the characteristics
of living things is this boy
demonstrating?
Grow and develop
Your blood sugar is low and you stop at Taco John’s
for a late night snack. Your blood sugar goes back up.
Which of the characteristics of living things is this an
example of?
Respond to stimulus & homeostasis
The carbohydrate molecule that
cells burn to release energy is
_______________.
glucose
Give an example of a monosaccharide
Glucose, galactose, fructose,
ribose, deoxyribose,
carbohydrate
A monosaccharide is a ______________
Lipid
nucleic acid
carbohydrate
protein
Many genetic diseases result from the production of
enzymes that are not shaped correctly. How could a
change in an enzyme’s shape cause it to work poorly or
not at all?
Changing its shape can alter the shape of the
active site which affects how the enzyme functions
Which of the following is TRUE?
Simple sugars are made of polysaccharides.
F Simple sugars are monosaccharides.
Polysaccharides are complex carbo’s made of many sugars.
RNA molecules are made of nucleotides.
TRUE
Amino acids are made of proteins
F Proteins are made of amino acids
Glycogen, starch, and cellulose are made of glucose.
TRUE
In polymerization, complex molecules are
formed by the joining together of
_______________
D. monomers
A. macromolecules
B. carbohydrates
C. polymers
D. monomers
Proteins that act as biological catalysts
enzymes
decreasing
Enzymes work by ____________
the activation energy required to
get a chemical reaction started.
increasing
decreasing
↑
Which of these molecules is a nucleotide?
Describes molecules that try to stay
away from water or other polar
molecules
Hydrophobic; non-polar
Scale used to measure acidity
pH
↑
Which of these molecules is a nucleic acid?
↑
Which of these molecules stores genetic info?
http://www.lincoln.midcoast.com/~del/butterfly
Which of the characteristics
of living things is this
butterfly demonstrating?
Grow and develop
People with diabetes lack the ability to
make this hormone that controls blood
sugar
insulin
↑
Which of these molecules is a carbohydrate?
Name the 2 kinds of nucleic acids
you learned about.
DNA and RNA
Give an example of a polysaccharide
Cellulose, glycogen, starch
Which of these molecules is a polysaccharide?
Which of these molecules is used by cells
to store and transport energy?
Structural polysaccharide used to
make plants sturdy
cellulose
Special kind of nucleotide used by
cells to store the energy released
from burning glucose.
ATP
RIBOSE
Image by Riedell
http://school.discovery.com/clipart/clip/ani-turtle.html
Another name for
a “living thing”
organism
Particle found in the nucleus of
an atom with a positive charge
proton
Unfolding that happens to a protein
in extreme temperatures or pH that
causes it to change shape
denaturing
Stimulus that comes from outside
an organism
External stimulus
An organized way of using
evidence to learn about the
natural world
science
A short DNA segment that gives
the instructions for a protein
gene
What does DNA stand for?
Deoxyribonucleic acid
The 3 smaller particles found inside
neutrons
atoms are ____________,
_____________.
protons
and _____________.
electrons
Give an example of an autotroph.
Green plant
The hereditary information in
all living things is in the form
of a large molecule called
DNA
(deoxyribonucleic acid)
__________________________.
heterotroph
A human is a(n) ______________.
autotroph
heterotroph
Name 5 of the characteristics of
ALL living things.
Made of cells
Reproduce
Take in and use materials and energy
Maintain stable internal conditions (homeostasis)
Grow and develop
Respond to environment
Have a universal genetic code
As a group, change over time
↑
Which of these molecules combines with
proteins to make cell membranes?
Give the chemical symbol for each:
C
Carbon _____
O
Oxygen _____
N
Nitrogen ____
P
Phosphorus ____
H
Hydrogen ___
S
Sulphur ___
+
Na
Sodium ion ____
+
K
Potassium ion ___
Cl
Chloride ion ___
++
Ca
Calcium ion ___
+
Hydrogen ion H
___
How many different amino acids are
used by all living things to make
proteins?
20
This gray fish is
Heterotroph
a(n)____________
(Gets its food by eating other organisms)
Autotroph
Image from: http://www.epa.gov/region5/superfund/ecology/images/fishcartoon.gif
heterotroph
Electrons orbit the nucleus of an
__________
atom at very high speeds in
different energy levels.
Protons
neutrons
electrons
An atom that has gained or lost
electrons so that is has an electric
charge on it is called an ______.
ion
Name one characteristic of water
that makes it important for living cells.
Good solvent
(lots of substances dissolve in it)
Can absorb lots of heat without changing temp
(good for homeostasis)
Makes hydrogen bonds
(water molecules stick together)
Participant/product in many chemical
reactions (helps metabolism)
↑
Which of these molecules could be used to
make glycogen, starch, or cellulose?
An organized way of using evidence
to learn about the natural world =
_________________
science
Large molecule made by joining
monomers together by polymerization
polymer
Name the 4 molecules that are
important for all living things
Proteins, carbohydrates,
lipids, nucleic acids
Lipids that are made of many carbon and
hydrogen atoms are
_________________
Non polar
Polar
non-polar
Match the building block with the molecule it makes.
Proteins
nucleic acids
lipids
carbohydrates
Nucleotide and amino acid images by Riedell
Nucleic
acids
____________________
Proteins
____________________
Carbohydrates
____________________
Glucose from: http://www.estrellamountain.edu/faculty/farabee/biobk/BioBookCHEM2.html
Give a function for nucleic acids in cells
Store and transfer info
Name an ion that’s important in
living cells.
+
Sodium (Na )
Calcium (Ca++)
+
Potassium (K )
Chloride (Cl )
Hydrogen (H+)
Which of these molecules could be used to
make an RNA molecule?
Carbon is an important atom
____________
to living things because it can form
bonds with 4 other atoms at once
to make chains, rings, and many
different kinds of molecules.
Name 4 of the 6 atoms important
for making molecules used in cells.
Carbon, nitrogen, hydrogen, oxygen,
sulfur, OR phosphorus
Name the 3 parts of a nucleotide
#1
#3
#2
nitrogen base (A, T, C, G, or U)
#1 = __________________
Sugar (deoxyribose or ribose)
#2 = __________________
phosphate
#3 = __________________
Double stranded nucleic acid molecule
containing A, T, C, G nitrogen bases
found in chromosomes that stores
genetic information
DNA
http://web.mit.edu/esgbio/www/lm/sugars/sugars.html
Macromolecule made by joining
MANY sugar molecules together in a
chain
polysaccharide
Amino acid subunits join together
proteins
to make _______________
Lipids
carbohydrates
nucleic
acids
proteins
Adenine, Thymine, Cytosine,
Guanine, and Uracil are used to make
Nucleic acids
_____________________
polysaccharides
amino acids
nucleotides
lipids
HEMOGLOBIN that carries oxygen
in your blood, INSULIN that helps
cells store sugar, and DIGESTIVE
proteins
ENZYMES are all _____________.
Proteins
carbohydrates
nucleic
acids
lipids
carbohydrate
Glucose is a _______________.
Protein
carbohydrate
nucleic
acid
lipid
Name one of the 3 functions of
proteins that you learned about
Act as enzymes
Transport (Help move substances in & out of cells)
Help synthesize other proteins (part of ribosomes)
Movement (make up cytoskeleton, cilia, flagella)
Act as hormones
Help cells recognize self (glycoproteins)
structural (make cell membranes)
Fight germs (antibodies)
Name a function of carbohydrates in
cells.
Burn for energy
Store energy for later
Structural (cellulose makes plants sturdy)
Cell ID (part of glycoproteins)
The subunits that make nucleic acids
nucleotides
are called _____________
amino acids
carbohydrates
nucleotides
Glucose, sucrose, glycogen, and
starch are all examples of
________________.
carbohydrates
The blue part of
this phospholipid
molecule
is ____________
Non-polar
polar
non-polar
Give an example of a heterotroph.
Any animal OR most bacteria
Phospholipids that make
up cell membranes have
a polar _________.
head
head
tail
Nucleic acid molecule that is single
stranded RNA
What determines the amino acid
sequence in a protein?
DNA code
What ending is found at the end of the
name of most enzymes?
-ase
What determines the 3D folding of
a protein?
Hydrophobic R groups
Nucleic acid molecule that is single
stranded RNA
Which of these molecules is a protein?
What property of carbon allows it to
form so many different kinds of
molecules?
Can join 4 other atoms at same time
What are some factors that can
influence an enzyme’s activity?
Temperature & pH
Which of these molecules is a phospholipid?
Which of the following is TRUE?
Catalysts slow down the rate of chemical reactions.
F Catalysts speed up the rate of reactions
All catalysts are enzymes.
F Only catalysts in living organisms are enzymes
Catalysts are used up during a chemical reaction
F Catalysts are released unchanged after the reaction.
Catalysts lower the activation energy of a reaction.
TRUE
Which of these molecules is an amino acid?
Name one of the properties of water that
make it important for living things
Its polar
so it dissolves many different substances
It doesn’t change temperature easily
so it helps in homeostasis (maintaining temp)
It forms hydrogen bonds
so molecules stick together
It is an important participant/product
in many chemical reactions
Tell one way DNA is different from RNA
DNA
Double stranded
Contains A,T,C,G
No U
sugar = deoxyribose
Stores genetic info
RNA
single stranded
Contains A,U,C,G
no T
sugar = ribosose
transfers info
from nucleus to
out to cell
Name the following in the enzyme catalyzed reaction:
Image by Riedell
enzyme
A = ________________
B = ________________
active site
C = ________________
substrate
enyzme-substrate complex
D = ________________
products
E = ________________
The process of changing from a stem
cell to different looking cells with
different functions
differentiation
Name the 4 main macromolecules used
to make living things
Carbohydrates, lipids, proteins,
& nucleic acids
The subunits made of a nitrogen
base, and sugar, and a phosphate
group used to make nucleic acids
nucleotides
Polysaccharide used by animal cells
to store glucose for later
glycogen
http://www.msu.edu/course/lbs/145/smith/s02/graphics/campbell_5.6.gif
Organism that can capture energy from
sunlight or chemicals and use it to
produce its own food; also called a
producer
autotroph
Process in which offspring are
produced by combining genetic material
from 2 parents
Sexual reproduction
Kind of lipid made from carbon and
hydrogen joined in rings instead of
chains that make up cell membranes and
can act as hormones
steroids
http://media.pearsoncmg.com/bc/bc_campbell_essentials_2/cipl/03/HTML/source/03-16-steroids-nl.htm
Carbohydrate molecule like glucose
that is made from only ONE sugar
molecule
monosaccharide
Scale used to measure acidity
pH
Molecule formed when a substrate bonds
to the active site of an enzyme
Enzyme-substrate complex
Organism that obtains energy from
the food it consumes; also called
a consumer
heterotroph
Process in which offspring are
produced from the genetic material
of a single parent
Asexual reproduction
http://faculty.stcc.edu/rapp/biol102/biology_links.htm
Molecule that is REALLY,
REALLY BIG
macromolecule
Stimulus that comes from inside
an organism
internal stimulus
Another name for a heterotroph
consumer
Atomic particle with a negative
charge electron
A signal to which an
organism responds
stimulus
Image from: http://www.travel-net.com/~andrews/images/animations/traffic.gif
Change in an organism over time;
Process by which modern organisms
have descended from ancient
organisms
evolution
Place in an atom where electrons
orbit
Energy levels
Name this reaction
http://io.uwinnipeg.ca/~simmons/macromol/sld003.htm
dehydration synthesis
The basic unit of life is the ________.
cell
The process in which cells change
as they grow and develop to
become specialized with different
functions
differentiation
http://www.ncu.edu.tw/~ls/graph/faculty_pictures/whole_time/SLC/SLC_lab-1.jpg
Embryonic cell that has the
potential to differentiate into a
variety cell types
Stem cell
Reactant that binds to the active
site of an enzyme during a
chemical reaction
substrate
Another name for an autotroph
producer
Neutral particle found in the
nucleus of an atom neutron
Molecule such as glycogen, starch, or
cellulose, made by joining many
monosaccharide (sugar) molecules
together polysaccharide
http://fig.cox.miami.edu/~cmallery/150/chemistry/fig5x27b.jpg
5 carbon sugar used to
make RNA
ribose
Macromolecule made of a polar
glycerol phosphate head and
non- polar tails used to
make cell membranes
phospholipid
Image by Riedell
All the chemical reactions through
which an organism builds up or
breaks down materials as it carries out
its life processes
metabolism
Organism made of many cells
multicellular
Molecules found in living things
that contain CARBON
organic
Protein that carries oxygen found
in red blood cells
hemoglobin
Kind of chemical reaction used by cells
to join molecules together by removing
an H and OH to make a water molecule
Dehydration synthesis
http://www.chemicalconnection.org.uk/chemistry/topics/images/pp3.jpg
Process by which organisms maintain a
relatively stable internal environment
homeostasis
Substances produced during a chemical
reaction that are found on the right
side of a chemical equation
products
Describes a polar molecule that mixes
easily with water; means “water
loving”
hydrophilic
Small unit that can join together with
other small units to form polymers
monomer
Image by Riedell
The carbohydrate molecule that
cells burn to release energy
glucose
Place on an enzyme where the
substrate attaches
Active site
http://www.biologie.uni-hamburg.de/b-online/library/cat-removed/enzyme_.gif
http://faculty.clintoncc.suny.edu/faculty/Michael.Gregory/files/Bio%20101/Bio%20101%20Lectures/Membranes/membrane.htm
Molecule made of a protein with
carbohydrates attached found
in cell membranes that helps
in cell identification
glycoprotein
Protein hormone, missing in people
with diabetes, that tells cells to store
glucose as glycogen
insulin
Double stranded nucleic acid molecule
containing A, T, C, G nitrogen bases
found in chromosomes that stores
genetic information
DNA
Macromolecule made by joining
MANY sugar molecules together in a
chain
polysaccharide
http://web.mit.edu/esgbio/www/lm/sugars/sugars.html
Energy required to get a
chemical reaction started
http://www.chuckwagondiner.com/art/matches.jpg
Activation energy
Attraction between oppositely
charged regions of nearby molecules
Van der Waals forces
Substance that speeds up a chemical
reaction by decreasing the
activation energy
catalyst
The process plants use to capture
energy from the sun and make glucose
photosynthesis
Organism made of only one cell
unicellular
Chemical reaction in which a molecule
is broken apart by the addition of the
H and OH from a water molecule
hydrolysis
Protein that acts as a biological
catalyst in living things to help
chemical reactions happen faster
enzyme
Attraction between oppositely charged
regions of nearby molecules involving
the hydrogen atoms of one molecule
and the partially
negatively charged
atoms in another
molecule
Hydrogen bonds
Images from: http://www.estrellamountain.edu/faculty/farabee/biobk/BioBookCHEM2.html
Macromolecule that contains carbon,
hydrogen, oxygen, and nitrogen, made
by joining amino acid subunits
protein
Molecule with an uneven pattern of
electric charges; More + on one side/
more – on the other
polar
Image from: http://www.estrellamountain.edu/faculty/farabee/biobk/BioBookCHEM2.html
Image from: http://fig.cox.miami.edu/~cmallery/150/chemistry/fig5x27b.jpg
5 carbon sugar used to make DNA
deoxyribose
An atom that has gained or lost
electrons so it has an electric charge
ion
Substances on the left side of a
chemical equation which react
reactants
Describes a non-polar molecule that tries to
stay away from water;
hydrophobic
means “water fearing”
One of the components (including
adenine, thymine, guanine, cytosine,
or uracil) that make up nucleotides
Nitrogen bases
Name this reaction
http://www.usd116.org/apalla/biology/unit3/notes/images/Hydrolysis.jpg
Compound made up of carbon, hydrogen, and
oxygen atoms usually in a ratio of
1 C: 2 H: 1 O which is a major source of
energy for the human body
carbohydrate
Large molecule made by joining
smaller monomer subunits together
polymer
Image by Riedell
Macromolecule made mainly of carbon and
hydrogen atoms; includes fats, oils, and
waxes and steroids, which is generally
hydrophobic
lipid
Macromolecule made of nucleotide subunits
containing carbon, hydrogen, oxygen,
nitrogen, and phosphorus which stores and
transports information in cells and helps
in protein synthesis
nucleic acid
Single stranded nucleic acid that contains
the sugar ribose and the nitrogen bases
adenine, guanine, cytosine, and uracil
RNA (ribonucleic acid)
Subunit used to make proteins made up
of a carbon atom attached to
a hydrogen,
a carboxyl group (-COOH),
an amino group
(-NH2) , and a variable R group
Amino acid
Image by Riedell
Polysaccharide used by PLANT cells
to store glucose for later
starch
http://bioweb.wku.edu/courses/BIOL115/Wyatt/Biochem/Carbos/Carb_poly.gif
The science of life (study of
living things) is called
_______________
biology
What does DNA stand for?
Deoxyribonucleic acid