Download Questions Ch 24

Chapter 24--control of microbial growth
3) Ampicillin is a semi-synthetic antibiotic derivative of penicillin G. Ampicillin is acidresistant, whereas penicillin G is not resistant to acid. Why is this important?
a) Ampicillin is resistant to β-lactamases.
b) Ampicillin can be taken orally.
c) Ampicillin is effective against Gram-negative bacteria.
d) Ampicillin is less toxic.
e) Ampicillin is more stable in solution.
4) The mode of action of β-lactam antibiotics in bacteria is directed against _____.
a) cell membrane synthesis.
b) peptidoglycan synthesis.
c) protein synthesis.
d) transcription.
e) DNA replication.
5) The mode of action of aminoglycosides is to inhibit __________ synthesis.
a) protein
b) RNA
c) DNA
d) membrane
e) peptidoglycan
6) β-lactam antibiotics bind to proteins located within the cell wall known as penicillin-binding
proteins (PBPs). The enzymatic action of PBPs is to function as a(a) _____.
a) ATP kinase.
b) dehydrogenase.
c) transpeptidase.
d) hydrolase.
e) isomerase.
10) The mode of action of sulfa drugs is to inhibit _____.
a) peptidoglycan synthesis.
b) folic acid biosynthesis.
c) transcription.
d) tryptophan biosynthesis.
e) protein synthesis.
9) The mode of action of quinolones is to inhibit _____.
a) protein synthesis.
b) DNA synthesis
c) cell wall synthesis.
d) amino acid transport.
e) transcription.