Download Polarised membrane A membrane with a potential difference across

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Transcript
Polarised membrane
A membrane with a potential difference across it.
This is the resting potential
Depolarisation
The loss of polarisation across the membrane. It
refers to the period when sodium ions are
entering the cell making the inside less negative
with respect to outside
Generator potential
A small depolarisation caused by sodium ions
entering the cell
Action potential
Achieved when the membrane is depolarised to a
value of about +40mV. It is an all-or-nothing
response. The membrane becomes depolarised
and reaches a threshold level, then lots of sodium
ions enter the axon.
Resting potential
The potential difference/voltage across the
neurone cell membrane while the neurone is at
rest. It is about -60mV inside the cell compared
with outside.
Voltage-gated channels
Channels in the cell membrane that allow the
passage of charged particles or ions. They have
a mechanism called a gate which can open and
close the channel. In these channels the gates
respond to changes in the potential difference
across the membrane.
Threshold potential
Potential difference across the membrane of
about -50mV. If the depolarisation of the
membrane does not reach this, then no action
potential is created.
Local currents
Movements of ions along the neurone. The flow
of ions is caused by an increase in concentration
at one point, which causes diffusion away from
the region of higher concentration.
Salutatory conduction
A “jumping conduction” that refers to the way that
the action potential appears to jump from one
node of Ranvier to the next.
node of Ranvier
A gap in the myelin sheath of a nerve, between
adjacent Schwann cells.
Hyperpolarisation
Is a change in a cell's membrane potential that
makes it more negative, caused by potassium
channels being slow to close. It is the opposite of
a depolarization. It inhibits action potentials.
Schwann cells
Cells that form a fatty material
called myelin to insulate the axons