Download How hereditary information is stored in the genome.

How hereditary information is
stored in the genome.
Three types of maps :
– Linkage maps of genes
– Banding pattern of chromosome
– DNA sequences
These maps lie on three very different types of
data:
– Observed pattern of heredity; gene or lingake group
transmission and recombination frequency.
– Identification of physical bands
– Physical sequence of nucleotides
High resolution maps
directly based on DNA markers.
A marker is any sequence variation
among individual that exists at a
defined position within the genome
and can be associated with individual
phenotypic characteristics.
The very great achievment
of biology is to find
connections between markers
and phenotypes.
Map Viewer
Software to visualize genomic or
chromosomic maps
Map Viewer
A software component of the Genome database
that provides special browsing capabilities for a
subset of organisms. You can view and search an
organism's complete genome, display chromosome
maps, and zoom into progressively greater levels
of detail, down to the sequence data for a region
of interest.
LINK RETE
Map Viewer Utility
1. To display maps from different types
of data;
2. To compare different kinds of data;
3. To follow links between them;
4. To compare map information from
different organisms.
Map Viewer access
1. Browsing by organism
2. Following links from various data
base (Nucletide, Gene, UniSTS..)
Browsing by group or by organism
Genome view
Advanced search
LOCALIZE THE CFTR GENE
IN THE MOUSE GENOME
Using MapViewer to localize
human FMR1 gene
• From the Map Viewer homepage,
select Homo sapiens (human), enter
FMR1.
• On the resulting genome page
several entries are returned.
Several entries
associated with
human FMR1 gene
• Focusing the query
gene through the
advanced search
3 hits
• Focusing the query
gene through
• Quick Filter
Table view
Sequence viewer
Genomic contig
Map selection through maps and options
How
can I obtain the genomic sequence
around my gene of interest?
1.
2.
3.
4.
Enter in MapViewer home page.
Refine search through advanced search.
Select the map (gene).
Dowload/View Sequence/Evidence
Map Viewer access
1. Browsing by organism
2. Following links from various data
base
Map Viewer access
Following links from various data base
OMIM (External Links
Genome)
Nucleotide (Related information)
Gene (Links)
UniSTS (in Mapping Information)