Download The Immune System

Warm-Up (12/09)
On the piece of white paper from the back, answer
the following question.
Explain how low insulin levels
lead to increased glucose
secretion into the blood in the
context of cell communication.
Be sure to include a discussion
on a change in gene
expression.
Name
Date
Period
The Immune System: war in your body
Mission: ID the enemy,
then kill it.
Method: make antibodies
that recognize
the enemy’s flag
(the antigen)
The Immune System: war in your body
the spies: B cells
the enemy: pathogens
antibody
antigen
The Immune System: war in your body
the enemy: pathogens
The Immune System: war in your body
the enemy: pathogens
The Immune System: war in your body
the enemy: pathogens
nucleus
poison
genes
antibody
receptor
Death
proteins
released
Critical Thinking Question #1
Discuss this question with your partner and write or
represent it. I will call on three people to share their
partners’ answers.
Explain how cells of the immune system
communicate with other cells.
The Immune System: war in your body
Humoral
System
B cells make
antibodies against
specific antigens
Cell-Mediated
System
T cells, a type of white
blood cells, recognize
antibodies and kill the
pathogens.
The Immune System: war in your body
Humoral
System
B cells make
antibodies against
specific antigens
New antibodies are
custom-made for
every new antigen
The Immune System: war in your body
Once antibodies are
made, a second
exposure to the same
antigen results in an
enhanced response.
Cell-Mediated
System
T cells, a type of white
blood cells, recognize
antibodies and kill the
pathogens.
Case in Point: Vaccines
Dead pathogen with
antigen attached →
B cells make antibodies →
fast T-cell response next
time.
Yo, that don’t
look like a
lollypop, and
it definitely
don’t feel like
a lollypop!
Examples: influenza (flu)
hepatitis C
tetanus
meningitis
Case in Point: Blood Types
Blood types can be A,
AB, B, or O
depending which
antigens are present
on your blood cells.
Organ donations can
also fail because the
wrong antigens are
present on the donor
organs.
Critical Thinking Question #2
Discuss this question with your partner and write or
represent it. I will call on three people to share their
partners’ answers.
Create a representation (cartoon, diagram,
et cetera) comparing and contrasting the
cell-mediated and humoral response.
Closure
On the piece of white paper from the
back, answer the following question:
Compare the immune
response to cell signaling:
which components are
analogous to ligands,
receptors, and cellular
response?
Name
Date
Period
Scale
1 – 10