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Transcript
ExternalElectiveChoicesforBiochemistryMajors
TherearecoursesinotherA&SUGprograms,andintheBiomedicalSciencesGraduateProgram
withintheSchoolofMedicine,thatcanbeusedasupperlevelelectivesfortheBiochemistry
degree.YoucanuseONEoftheseoutside-of-the-Biochemistry-departmentcoursesasan
upper-levelelectivetomeettherequirementsfortheprogram.
Pleasekeepinmindthatnotallofthesecoursesareofferedeveryyear;someareofferedin
alternateyears,andsomeareofferedonlywhentheinstructorhassufficientenrollment.Also,
yourenrollmentintoanyofthesecourseswillbeatthediscretionofthecourse
instructor.He/shemayhavetooverridepre-requisitecoursesandcapacities,andonlythe
instructorofrecordcanmakethisdetermination.
ExternalUndergraduateElectiveChoices
Biol410EcologyandEvolutionaryGenomics-Thiscoursefocusesonmethods,both
experimentalandcomputational,tostudythestructureofgenomesandtoanalyzegene
expressionandproteinfunctiononagenome-widescale.Computationaltopicsincludegraphic
approachesinsequenceassembly;discriminantanalysisingenefinding;dynamicprogramming
insequencecomparison;andclusteringtechniquesintheanalysisofgeneexpressiondata.
Biol412DevelopmentalBiology-Comparativebiologyofanimaldevelopmentemphasizing
regulatorymechanisms.
Biol461LHistology-Microscopicstructureofvertebratetissues,emphasizingcorrelationof
structureandfunction.
Biol425MolecularGenetics-Molecularbiologyofthegene.
Biol428HumanHeredity-Geneticprinciplesappliedtohumans.
Biol429MolecularCellBiology-Cellularprocesseswithemphasisonmembranes;includes
readingoriginallandmarkpapersincellbiology.
Biol437EvolutionaryGenetics-Mutation,naturalselection,geneticdrift;howevolutionary
forcesshapepopulationstructure.Mechanismsofspeciation.Macroevolutionofbiochemical
processesessentialtohigherorganisms,suchassignaltransductionpathways,developmental
genesandcomplexorgans.
Biol444GenomicsandGenomicAnalyses-OverviewofgenomicanalysesfromDNAsequence
togeneexpressionandproteomics.
Biol445BiologyofToxins-Principlesoftoxicology;pharmacologyandbiotransformationof
xenobiotics.Mechanismofaction,medicaluses,andevolutionaryecologyofbiologicaltoxins.
Biol446LaboratoryMethodsinMolecularBiology-PrinciplesofDNAandRNApurification,
enzymaticmanipulationofnucleicacids,molecularcloning,gelelectrophoresis,hybridization
proceduresandnucleotidesequencing.
Biol450GeneralVirology-Structure,properties,andmolecularbiologyofviruses;virus-host
interactions,multiplication,pathology,epidemiology,effectsofchemicalandphysicalagents,
classification.
Biol451MicrobialEcology-Roleofmicroorganismsinterrestrialandaquaticecosystems.
Emphasisonbiogeochemistryandnutrientcycling.
Biol452AnthropologicalGenetics(HumanGenetics)-Thiscourseexaminestheory,dataand
methodsusedbygeneticanthropologiststoaddressquestionsabouthumanoriginsand
prehistory,race,naturalselection,disease,andthesocialandscientificimplicationsofresearch
ingeneticanthropology.
Biol456Immunology-Immunoglobulinstructure,anitigen-antibodyreactions,immunityand
hypersensitivity;experimentalapproachwillbeemphasized.
Biol460MicrobialPhysiology-Physiologicalandbiochemicalactivitiesofbacteriaandfungi
withemphasisoncellenergetics.
Biol482LParasitology-Theprotozoaandwormsimportantinhumanandveterinarymedicine.
Emphasisonlifehistories,epidemiologyandecologyofparasiteswithlaboratorypracticein
identificationandexperimentation.
Biol490BiologyofInfectiousOrganisms-Thefullspectrumofinfectiousentitiesincluding
prions,virusesandparasiticprokaryotesandeukaryoteswillbediscussedwithrespecttotheir
transmissibility,interactionswithimmunesystemsandtheirinfluencesonevolutionary
processesandbiodiversityissues.
Biol497PrinciplesofGeneExpression-Adetailedandcriticalstudyofhowdifferentgenesare
regulatedduringthelifeofanorganism,principallyattheleveloftranscription.
Chem422MolecularBiologyoftheGene-Focusesonthebiologicalchemistryofgene
structure,expressionandregulationandthestructureandfunctionofthecellnucleus.
Chem425OrganicChemistryofBiologicalPathways-Coversbasicprinciplesofmechanisms,
acidity,stereochemistry;structures;propertiesofbiomolecules;reactionsinlipid,
carbohydrate,aminoacid,nucleotidemetabolicpathways.
Chem457EnvironmentalChemistry-Introductiontothechemistryofnaturalandpolluted
environments,includingbothatmosphericandaquaticsystems.
ExternalGraduateElectiveChoices
Ifyouchoosetoenrollinoneofthefollowingcoursesatthe500-levelcourse,additional
requirementsmustbemet.Coursesnumberedabove500arenormallyopenonlytograduate
students;however,seniorstudentswithGPAsof3.0orhighermayreceiveundergraduate
creditinthesecourses.Theymustobtainapprovalinadvancefromtheinstructorconcerned,
thechairofthedepartment,andthedeanoftheirundergraduatecollege.Undergraduatesmay
notenrollingraduate“Problems”coursesforundergraduatecredit.
Biomed509PrinciplesofNeurobiology-Thiscoursecoverscellularstructureofneuronsand
glia,theelectricalpropertiesofneurons,intercellularcommunication,andtheformation,
maintenanceandplasticityofchemicalsynapses.
Biomed510Physiology-Courseinregulatoryandsystemsbiology,andcardiovascularand
pulmonarybiology.
Biomed515CancerBiology-Fundamentalelementsofcancerdevelopmentandprogression
willbethefocusofthiscourse.Basicbiochemicalandgeneticmechanismsoftumorigenesis,
includinggenomicinstability,principlesoftumorcellinvasionandgrowthdysregulationwillbe
emphasized.
Biomed516MolecularGeneticsandGenomics-Coversgeneticandgenomicapproachesin
modelorganisms(prokaryotes,fungi,worms,mouseandfruitflies)andhumanstostudy
biologicalprocessesatthemolecular,cellular,tissue,organism,populationandevolutionary
levels.Providesanintroductiontobioinformaticandcomputationalmethodsusedinsuch
studies.
Biomed522ExperimentalDesignandMethodsinMolecularandCellularBiosciences-This
case-basedcourseisintendedforfirstyeargraduatestudentsandfocusesonpracticalissuesof
howtodesign,planandconductscientificstudiesthroughappropriateuseofexperimental
methodsanddataanalysis.
Biomed532Neurochemistry-Anintroductiontoneurochemistryandneuropharmacology,
withheavyemphasisonstudentparticipation,byreadingandevaluatingcurrentpublications.
Pharm576CellularandMolecularPharmacology(1credit)WITHPharm580General
Toxicology(2credits)–Mustbetakentogether.
•PHRM576.IntroductoryPharmacology.Pharmacologyisabasicscienceconcerned
withallaspectsoftheactionofdrugsonlivingsystems.Initsentirety,pharmacology
embracesbiochemicalandphysiologicaleffects,mechanismsofaction,
pharmacokinetics,andtherapeuticanddiagnosticusesofdrugs.Astrongworking
knowledgeofpharmacologyisessentialtotheprofessionalroleofpharmacistsandto
basicscientistsengagedindrugdiscoveryandunderstandinghowdrugswork.Thegoal
ofthiscourseistogiveanoverviewoftheprinciplesofmodernmolecularandcellular
pharmacology,aswellassomedetailsofdrugdelivery.Topicsinclude:
biopharmaceuticalpropertiesofdrugs;receptortheory;absorption,distribution,
metabolismandelimination;pharmacokineticsanddrugdelivery.Italsoservesasan
IntroductorycoursetoPHRM580andPHRM598courses
•PHRM580-GeneralToxicology.Toxicologyisanimportantbroad-baseddiscipline
thatincorporatesinformationfrommanyareasbridgingthegapbetweenmolecular
mechanismsoftoxinactivitytotheirimplicationsinreal-worldproblems.FortheSpring
2015semester,theGeneralToxicologycoursehasbeenrevampedtofocusonbasic
scientificliteraturerelevanttotoxicologyandthescientificmethodthatareofinterest
tograduatestudents.Scientificliteraturerelevanttotoxicologyandthescientific
methodareemphasizedinalltopicscovered.Thegoalofthiscourseistogivestudents
abroad,butcomprehensive,overviewoftheprinciplesoftoxicology.Topicswillbe
taughtbyexpertsineachareaandwillincludeaspectsoftoxicologyonrelevanttoxic
agents,molecularandcell-basedmechanismsofaction,aswellasdetailsoftargetorgan
systemsandphysiologythatareaffectedbytoxins.