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http://download.elearningontario.ca/repository/1235730000/SBI3UPU03/SBI3UPU03A03/overview.ht ml SBI3U: Biology, Grade 11, University Preparation Unit 3: Evolution Activity 3: Mechanisms for Evolution Overview | Expectations | Content | Assignment Overview In this activity you will learn about adaptation and how it is vital to natural selection. You will also learn how random changes can occur in a population, but how natural selection is not random, instead selecting for survival of the fittest. At the end of this activity you will complete a lab where you will observe selection on a micro level. SBI3U: Biology, Grade 11, University Preparation Unit 3: Evolution Activity 3: Mechanisms for Evolution Overview | Expectations | Content | Assignment Content In the previous activity you learned about how the organisms that are most fit for a particular environmental change have a better chance to survive long enough to produce offspring. But, how is it that one individual’s fitness can translate into a permanent genetic change that is passed on from generation to generation? Did you know? Sickle cell anaemia is caused by a mutation in a gene that makes haemoglobin. The allele that causes the disease occurs most frequently in parts of the world where malaria is common. In these areas, sickle cell anaemia carriers are naturally selected because carrying the trait gives them some immunity to malaria. Although sickle cell anaemia greatly curtails life span, individuals who carry the trait have some immunity to malaria and on average live longer with the trait than without. This is an example of natural selection. Variation Recall from genetics that alleles are alternate forms of the same gene. Alleles can be created by random mutations in the DNA. If the mutated alleles are harmful to the organism, usually the organism will die. However organisms that have the beneficial mutation may be naturally selected. A variety of molluscs Here is one species of mollusc, Donax variabilis. Within this species there is variability in the phenotype of the shells. This variability likely originated from point mutations in the DNA of these molluscs. If you were to take the frequencies of how many times these phenotypes appear in the population of molluscs and graph them, you would probably obtain a curve that shows a normal distribution like the one on the right A normal distribution curve showing the percentage of variation/deviation under the curve. This graph shows continuous variation within a population. Adaptation An adaptation is a genetic variation that allows for a population to be favoured by natural selection. The ability of an organism to change its phenotype in response to different environmental conditions is called phenotypic plasticity. The phenotypic plasticity seen in the Donax in the illustration above allows them to live in a variety of conditions. Changes in the conditions may cause one type of shell colouration to be favoured over another. Thus the shape of the normal distribution curve might shift to the right or left, or even split in the middle. Hardy-Weinburg Principle After a dialogue with Reginald Punnett, two mathematicians, Godfrey Hardy and Wilhelm Weinberg, came up with a solution to identify the frequency of each allele in a population. They showed that there was a mathematical relationship between two alleles in a population and that the allele frequencies would not change from generation to generation unless there are disruptive influences. This relationship is known as the Hardy-Weinburg Principle and holds true if: populations are large; there are equal opportunities for mating; no migration occurs; no mutations occur; no natural selection, but equal opportunity for all. Under these conditions a given gene pool remains the same from generation to generation. This does not allow for much evolutionary change. Let’s look at conditions where the Hardy-Weinburg Principle does not apply: 1. Genetic Drift When populations are small and some individuals leave the population, this reduces the frequency of certain alleles in the population. For instance, in the island scenario from the previous activity, what if two of the eleven individuals can overcome an infection (they carry the alleles to do this) that strikes all the people. However they decide to build a raft and leave the island. This would affect the frequency of this particular allele in this small population. There is a chance that no one would survive, and those two individuals would not pass on these alleles to the next generation. This is an example of genetic drift. In severe situations, genetic drift can give way to the bottleneck effect and founder effect. Learn more on Bottleneck Effect, Founder Effect and Genetic Drift Bottleneck Effect Founder Effect Genetic Drift Portfolio: Notes help prepare you for tests. Keep all of your notes in your portfolio. Be prepared to submit your portfolio notes and organizers to your teacher for assessment at various times during the course. Use your portfolio to make detailed notes on Bottleneck Effect, Founder Effect and Genetic Drift. 2. Gene Flow/Migration When organisms migrate from one population to another, this can alter the frequency of alleles in both populations. This is termed gene flow. Gene flow can also occur when individuals from two populations mate without moving. When this occurs, gene flow can make populations more similar. 3. Mutation Mutations allow for new alleles to be formed. Mutations can be beneficial and allow organisms to adapt to change. They can be neutral or they can be harmful and not allow the organism to be more fit, but rather adversely affect their chances of survival. You have learned of several types of mutations such as point mutations, translocations, inversions, deletions, and duplications. Those that affect evolution are gene duplication, pseudogenes, and polyploidy. Learn more on the mutations that affect evolution. Pseudogenes Polyploidy Evolution by Polyploidy 4. Natural Selection Natural selection is a mechanism of evolution. Before natural selection can occur, there needs to be variation in a population’s gene pool. Variation means that there are multiple alleles in a population. Some changes in the environment will result in individuals with alleles that code for traits that suit the new environment and therefore be more fit to survive. The survivors will pass on their genes to the next generation. When members of a population separate from the original population, they face new environmental challenges and new traits may be advantageous. The genes coding for these traits will be passed on to the next generation. Populations of individuals can become more varied from each other since the gene flow between the populations is not possible. Increased differences can ultimately lead to speciation (the formation of two genetically unique species) and these two populations can no longer mate due to genetic differences. Extinction In Activity 2 you learned about extinction. You also researched some of the factors that cause extinction such as loss of habitat, loss of food source, and environmental change. Unfortunately, these species will be lost from the planet forever. In terms of evolution, however, extinction is not necessarily considered negative. Can you think why this is? Learn more on Natural Selection and Extinction Natural Selection Extinction Portfolio: Notes help prepare you for tests. Keep all of your notes in your portfolio. Be prepared to submit your portfolio notes and organizers to your teacher for assessment at various times during the course. Use your portfolio to make detailed notes on Gene duplication, Polyploidy, Evolution by Polyploidy and Extinction. Try this simulation lab: http://download.elearningontario.ca/repository/1235730000/SBI3UPU03/SBI3UPU03A03/mme/natura lsel/preloader.html