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Name: Date: Period: FRQ practice The unit of genetic organization in all living organisms is the chromosome. (a) Describe the structure and function of the parts of a eukaryotic chromosome. You may wish to include a diagram as part of your description. (b) Describe the adaptive (evolutionary) significance of organizing genes into chromosomes. (c) How does the function and structure of the chromosome differ in prokaryotes? 2005 Genetic Essay Question Rubric The unit of genetic organization in all living organisms is the chromosome. (a) Describe the structure and function of the parts of a eukaryotic chromosome. You may wish to include a diagram as part of your description. (b) Describe the adaptive (evolutionary) significance of organizing genes into chromosomes. (c) How does the function and structure of the chromosome differ in prokaryotes? Part A: 5 Points Maximum ______Chromatid structure: 2/ sister/ pair/ identical DNA/ genetic information ______Chromatid function: distribution of one copy to each new cell ______Centromere structure: noncoding/ uncoiled/ narrow/ constricted/ region/ determines arm ratio ______Centromere function: joins/ holds/ attaches chromatids together ______Nucleosome Concept Structure: Histones, DNA wrapped around special proteins ______Nucleosome Concept Function: Packaging/ compacting ______Chromatin Form (heterochromatin/ euchromatin) structure: condensed supercoiled vs. loosely coiled. ______ Chromatin Form (heterochromatin/ euchromatin) function: proper distribution in cell division (not during replication)/ gene expression during interphase/ replication occurs when loosely packed ______Kinetochores structure: disc-shaped proteins ______Kinetochores function: spindle attachment/ alignment ______Genes or DNA structure: brief DNA description ______Genes or DNA function: codes for proteins or for RNA ______Telomeres structure: Tips, ends, noncoding repetitive sequences ______Telomeres function: protection against degradation/ aging, limits number of cell division NOTE: No points for just naming the component, for stating that chromosomes are made of genes and a diagram alone will not suffice but can be used for clarification. Part B: 4 Points Maximum, 2 Points Per Theme • Allows for Genetic Variation ______through independent assortment (brief description) ______through crossing over (brief description) ______leads to variation in gametes • Allows for Genetic Stability ______efficiency of transfer of genetic information ______prevents loss of genetic information ______offspring get same number of chromosomes ______maintains integrity of chromosomes ______linked genes tend to be inherited together • Allows for Gene Regulation ______increased complex structure ______histone acetylating ______methylation • Allows for Complexity ______allows for more genes ______evolution of new genes can occur/transposons ______intron/ exon allows for alternate splicing • Allows for Diploid/Polyploid ______genetic fitness ______minimizes the effect of harmful alleles/ backup copy ______extra set(s) of alleles ______heterozygosity Part C: 4 Points Maximum ______shape (circular/ nonlinear/loop) ______less complex (no histones/less elaborate structure/folding) ______size (smaller size/less genetic information/fewer genes) ______replication method (single origin of replication/ theta replication) ______transcription/translation may be coupled ______generally few or no introns (noncoding) ______majority of genome expressed ______operons – gene regulation NOTE: No points for plasmids – more common but not unique to prokaryotes/ not part of prokaryote chromosome.