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Transcript
405-S3-MSS05_LBA
08/19/2004
11:34 AM
Page 144
Recombinant DNA Making recombinant DNA is one
Genetically Engineered
Crops Crop plants are
now being genetically
engineered to produce
chemicals that kill specific pests that feed on
them. Some of the pollen
from pesticide-resistant
canola crops is capable of
spreading up to 8 km
from the plant, while
corn and potato pollen
can spread up to 1 km.
What might be the
effects of pollen landing
on other plants?
method of genetic engineering. Recombinant DNA is made by
inserting a useful segment of DNA from one organism into a
bacterium, as illustrated in Figure 12. Large quantities of human
insulin are made by some genetically engineered organisms.
People with Type 1 diabetes need this insulin because their
pancreases produce too little or no insulin. Other uses include
the production of growth hormone to treat dwarfism and
chemicals to treat cancer.
Gene Therapy Gene therapy is a kind of genetic engineering.
In gene therapy, a normal allele is placed in a virus, as shown in
Figure 13. The virus then delivers the normal allele when it
infects its target cell. The normal allele replaces the defective
one. Scientists are conducting experiments that use this method
to test ways of controlling cystic fibrosis and some kinds of cancer. More than 2,000 people already have taken part in gene
therapy experiments. Gene therapy might be a method of curing several other genetic disorders in the future.
Normal gene
+
Cold virus
Figure 13 Gene therapy involves
placing a normal allele into a cell
that has a mutation. When the
normal allele begins to function, a
genetic disorder such as cystic
fibrosis (CF) may be corrected.
Normal gene
inserted into
cold virus
Nucleus
Nasal cell
Normal gene
Lung
144
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A
CHAPTER 5 Heredity