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Professor: Roe S.I. Leader: Stephanie Schneider Biology 211 (1) Exam 4! ! Chapter 12! 1. Why does replication occurs in an uncondensed state?! 1. ! 2. A ___________ is a single strand of DNA. When DNA is added to associated protein molecules, it is referred to as __________.! ! ! 3. Diagram the cell cycle, labeling the G1, G2, S and M phases.! 4. Chromosome replication occurs only during _______ phase.! 5. Describe each phase of mitosis in the following chart:! Mitotic Phase ! (In Order) Description Drawing Page 1 of 7 Professor: Roe Mitotic Phase ! (In Order) S.I. Leader: Stephanie Schneider Description Drawing 6. Compare and contrast G1, G2 and M checkpoints. Why is it important for the cell cycle to have checkpoints?! 1. ! 7. What is the difference between polar microtubules and kinetochore microtubules?! 1. Polar microtubules:! 2. Kinetochore microtubules:! 8. What is p53? What would happen to a cell that has a damaged p53 gene so that it ! cannot make functional p53 protein?! 9. _______ tumors are not cancerous. _______ tumors are cancerous and go through _______, which is when the cancer moves to other parts of the body and create a new tumor. Page 2 of 7 Professor: Roe S.I. Leader: Stephanie Schneider Chapter 13! 1. Complete the crossword puzzle found on https://apps-dso.sws.iastate.edu/si/ course.php?id=914. The crossword puzzle is named “Chapter 13 Worksheet.” 2. Briefly describe the different processes in Meiosis—Meiosis I and Meiosis II. a. ! 3. How many and what ploidy of daughter cells are produced during Meiosis? a. ! 4. What is the difference during Metaphase I and Metaphase II of Meiosis? a. Metaphase I: b. Metaphase II: Page 3 of 7 Professor: Roe S.I. Leader: Stephanie Schneider Chapter 14! 1. Compare and contrast the concepts of particulate inheritance and blending inheritance. a. Blending Inheritance: b. Particulate Inheritance: 2. What would eventually happen if the blending theory of inheritance was true? a. ! 3. Who provided the groundwork of basic genetics? Which hypothesis was supported by his experiments? a. ! 4. What does it mean to have a “true-breeding” parent? a. ! 5. What is the difference between genes and alleles? a. ! 6. Alleles can either be _________ or __________. 7. Compare and contrast genotype and phenotype. Is “Aa” heterozygous or homozygous and is it a genotype or phenotype? Is “A” a dominant or a recessive allele? a. ! 8. Do individuals with the same genotype always have the same phenotype? Why or why not? a. ! 9. Are pure-line peas homozygous or heterozygous? Do the terms homozygous and heterozygous describe an organism’s genotype or phenotype? a. ! 10. What is the purpose of a test cross? a. ! 11. What is the ratio of phenotypes in the F2 generation if you begin with pure line yellow-seeded plants (YY) and pure-line green-seeded plants (yy). What is the genotype ratio in the F1 and F2 generations? Draw Punnett Squares to help answer the problem. Page 4 of 7 Professor: Roe a. Parent 1: (YY) S.I. Leader: Stephanie Schneider Parent 2: (yy) b. F1 ! ! ! ! c. F2 ! ! ! ! d. Ratio of phenotypes in F2—> e. Genotype ratio in F1—> f. Genotype ratio in F2—> 12. One parent is homozygous dominant for two traits: round and yellow seeds. The other parent is homozygous recessive for those two traits: round and yellow seeds. Create a dihybrid cross for the F2 Generation of the true breeding parents. 13. Describe the Law of Segregation and the Law of Independent Assortment. a. Law of Segregation: b. Law of Independent Assortment: 14. Define each of the following terms: complete dominance, incomplete dominance, codominance. a. Complete dominance: Page 5 of 7 Professor: Roe S.I. Leader: Stephanie Schneider b. Incomplete dominance: c. Codominance: 15. Why is incomplete dominance not blending inheritance? a. ! 16. ________ is when individual genes affect more than one phenotypic character. What is an example of this? a. ! ! Page 6 of 7 Professor: Roe S.I. Leader: Stephanie Schneider Chromosomal Basis of Inheritance! 1. __________ described the process of meiosis in 1876. __________ described the significance of meiosis in cell division in 1890. __________ was the first scientist to support Mendel’s laws between 1877 and 1916. ___________ was skeptical about Mendelian genetics and did experiments using Drosophila melanogaster (fruit fly). 2. What does the Chromosome Theory of Heredity propose? a. ! 3. Define the following terminology: a. Wildtype: b. Mutant: c. Vestigial: 4. Eye color is linked to the sex of the individual. Only the _____ chromosome has a copy of that gene. 5. What would the genotype and phenotype of a female fly with white eyes be if it was crossed with a male that had X(W+) and Y chromosomes. a. Genotype: b. Phenotype: 6. ________________ are genes located on the same chromosome that tend to be inherited together. Page 7 of 7