Download Application Sheet: DNA - NETZSCH Thermal Analysis

APPLICATION SHEET
ORGANICS – PHARMACEUTICALS
DNA
NGB ∙ AS ∙ 135-2006 ∙ EN ∙ 07/13 ∙ Technical specifications are subject to change.
DNA is a long polymer of simple units called nucleotides,
which are held together by a backbone made of sugars
and phosphate groups. This backbone carries four types
of molecules called bases and it is the sequence of these
four bases that encodes information. The major function
of DNA is to encode the sequence of amino acid residues
in proteins, using the genetic code.
Instrument
DSC 204 F1 Phoenix®
Test Conditions
Temperature range
Heating rate
Atmosphere
Sample mass
Crucible
Results
5 ... 250°C
5 K/min
Nitrogen at 20 ml/min
1.38 mg (+ 4.16mg water)
Al, closed
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Two endothermic effects were detected between 80
and 90°C. The first one at 81.2°C (peak temperature) has
an enthalpy of 0.02 J/g. The second occurring at 84°C is
associated with an enthalpy of 0.53 J/g. It is most probably
due to the DNA denaturation.