* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download BIO 219 Spring 2013 Outline for “Cell Metabolism” Energy (ATP
Gaseous signaling molecules wikipedia , lookup
Protein–protein interaction wikipedia , lookup
Nicotinamide adenine dinucleotide wikipedia , lookup
Fatty acid metabolism wikipedia , lookup
Biosynthesis wikipedia , lookup
NADH:ubiquinone oxidoreductase (H+-translocating) wikipedia , lookup
Proteolysis wikipedia , lookup
Signal transduction wikipedia , lookup
Butyric acid wikipedia , lookup
Photosynthesis wikipedia , lookup
Photosynthetic reaction centre wikipedia , lookup
Biochemical cascade wikipedia , lookup
Metalloprotein wikipedia , lookup
Electron transport chain wikipedia , lookup
Light-dependent reactions wikipedia , lookup
Mitochondrion wikipedia , lookup
Basal metabolic rate wikipedia , lookup
Microbial metabolism wikipedia , lookup
Adenosine triphosphate wikipedia , lookup
Citric acid cycle wikipedia , lookup
Biochemistry wikipedia , lookup
Oxidative phosphorylation wikipedia , lookup
Evolution of metal ions in biological systems wikipedia , lookup
BIO 219 Spring 2013 Outline for “Cell Metabolism” Energy (ATP) Where do we get it? Why do we need it? Types of cell metabolism Anaerobic vs. Aerobic respiration Glucose metabolism 4 steps of cellular respiration (aerobic) Glycolysis (cytoplasm) Energy investment phase & energy-yielding phase Net yield Pyruvate metabolism (mitochondria) Pyruvic acid → Acetyl CoA Oxygen (Why do we need it?) Net yield Citric Acid Cycle (mitochondria) Eight-step process Oxygen (Why do we need it?) Net yield Electron Transport Chain (mitochondria) Five integral membrane proteins NADH & FADH2 Oxygen (Why do we need it?) Net yield Fermentation Glycolysis Lactic acid production What about fats and proteins as an energy source? Objectives: By the end of lecture today you should be able to . . . (1) Describe the similarities and differences between aerobic and anaerobic metabolism. (2) What does ATP stand for? Describe its general structure. (3) What are the four steps of aerobic cellular respiration? What happens in each step? What is the starting molecule in each step? Where in the cell does each step occur? What is the net yield of products for each of these pathways? (4) What is the role of NADH and FADH2 in ATP production? What do NADH and FADH2 stand for? In other words, be able to write out the proper scientific names for these molecules. (5) How does ATP synthase make ATP? In which “step” of cellular respiration does the synthase operate? (6) What is the role of oxygen in cellular respiration? (7) When is anaerobic fermentation used to make ATP? What is the end product of fermentation? Is fermentation as efficient as cellular respiration in making ATP? (8) How can fat and protein catabolism contribute to ATP production? Assuming oxygen is present, what biochemical pathway(s) would the protein or lipid metabolites utilize?