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Download SUZ12 antibody - middle region (ARP32515_P050)
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SUZ12 antibody - middle region (ARP32515_P050) Data Sheet Product Number Product Name Size Gene Symbol Alias Symbols Nucleotide Accession# Protein Size (# AA) Molecular Weight Product Format NCBI Gene Id Host Clonality Official Gene Full Name Gene Family ARP32515_P050 SUZ12 antibody - middle region (ARP32515_P050) 50ug SUZ12 CHET9; JJAZ1; KIAA0160 NM_015355 739 amino acids 83kDa Lyophilized powder 23512 Rabbit Polyclonal Suppressor of zeste 12 homolog (Drosophila) ZNF Description This is a rabbit polyclonal antibody against SUZ12. It was validated on Western Blot using a cell lysate as a positive control. Aviva Systems Biology strives to provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (). Target Reference Li,H., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (50), 20001-20006 Partner Proteins Description of Target Additional Information Blocking Peptide Immunogen Lead Time EGFR, STAT3, ELK4, SRF, KHSRP, JAG1, JUN, JUN, RELA, ATF2, ATF7, BATF, BCL3, CEBPG, COBRA1, CSNK2A1, CSNK2A2, DDIT3, EEF1D, ELK1, ELK4, EPHB2, ETS1, FOS, GATA4, GTF2F2, HNF1A, JUN, JUNB, JUND, LMNA, MAF, MAP3K7, MAPK1, MITF, NCOA1, NCOR2, NFATC3, NFKB1, OPTN, PRKACA, PSMC5, RB1, RELA, RPS6KA1, RPS6K A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. Translocation t (7;17)(p15;q21) with JAZF1 generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region. The specific function of this gene has not yet been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. IHC Information: Paraffin embedded placenta tissue, tested with an antibody dilution of 5 ug/ml. For anti-SUZ12 antibody is Catalog # AAP32515 (Previous Catalog # AAPP03518) The immunogen for anti-SUZ12 antibody: synthetic peptide directed towards the middle region of human SUZ12 Domestic: within 24 hours delivery International: 3-5 business days Peptide Sequence Synthetic peptide located within the following region: TGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQ Reconstitution and Storage Swissprot Id Protein Name Add 50 ul of distilled water. Final anti-SUZ12 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles. Sample Type Confirmation Protein Accession # Purification Species Reactivity Application Predicted Homology Based on Immunogen Sequence Q15022 Polycomb protein SUZ12 SUZ12 is strongly supported by BioGPS gene expression data to be expressed in HeLa NP_056170 Affinity Purified Human, Pig, Bovine, Mouse, Dog, Horse, Rabbit, Rat, Guinea pig CHIP, IHC, WB Dog: 100%; Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Rabbit: 100%; Guinea pig: 93% Human Placenta Image 1 Placenta HCT116 Chromatin Immunoprecipitation (ChIP) Using SUZ12 antibody middle region (ARP32515_P050) and HCT116 Cells Image 2 Human HeLa WB Suggested Anti-SUZ12 Antibody Titration: 0.21 ug/ml Positive Control: Hela cell lysate Image 3 SUZ12 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells __________________________________________________________________________________________________________________________________________________________________ This product is for Research Use Only. Not for diagnostic, human, or veterinary use. Optimal conditions of its use should be determined by end users.