Carnitine metabolism and biosynthesis in yeast Saccharomyces
... metabolisation of in particular peroxisomally generated acetyl-CoA. This cycle results in the net production of succinate from two molecules of acetyl-CoA. This dicarboxylic acid can then enter the mitochondria for further metabolism. Partial disruption of the glyoxylate cycle, by deletion of the ci ...
... metabolisation of in particular peroxisomally generated acetyl-CoA. This cycle results in the net production of succinate from two molecules of acetyl-CoA. This dicarboxylic acid can then enter the mitochondria for further metabolism. Partial disruption of the glyoxylate cycle, by deletion of the ci ...
Towards functional effects of polyphenols : modulation of energy
... polyphenol aglycones and are therefore easily eliminated through bile and urine [36-38]. Chronic administration of selected polyphenols could possibly increase the systemic exposure considerably. Flavonols have plasma half lives of ~20h, whereas catechins and anthocyanins are eliminated 5-10 times f ...
... polyphenol aglycones and are therefore easily eliminated through bile and urine [36-38]. Chronic administration of selected polyphenols could possibly increase the systemic exposure considerably. Flavonols have plasma half lives of ~20h, whereas catechins and anthocyanins are eliminated 5-10 times f ...
Identification and first characterization of pairing
... severe damage and chronic inflammation of the according tissues, as eggs secrete lytic enzymes and serologically active proteins (Ashton et al., 2001; Schramm & Haas, 2010). A number of eggs are accidentally transported via the blood stream to inner organs such as the liver and spleen, where they ca ...
... severe damage and chronic inflammation of the according tissues, as eggs secrete lytic enzymes and serologically active proteins (Ashton et al., 2001; Schramm & Haas, 2010). A number of eggs are accidentally transported via the blood stream to inner organs such as the liver and spleen, where they ca ...
Xenopus Spinal Neurons Express Kv2 Potassium Channel
... respectively, suggesting that pXb4 is related to XShab9. The two nucleotide differences between XShab9 and pXb4 occur at the third position of a codon and do not cause amino acid changes (Fig. I/l). pXb3 is 76 and 97% identical to XShab9 and XShab12, respectively, indicating that pXb3 is related to ...
... respectively, suggesting that pXb4 is related to XShab9. The two nucleotide differences between XShab9 and pXb4 occur at the third position of a codon and do not cause amino acid changes (Fig. I/l). pXb3 is 76 and 97% identical to XShab9 and XShab12, respectively, indicating that pXb3 is related to ...
Glutamine metabolism and its effects on immune response
... severe sepsis definition includes, among other factors, the presence of two or more criteria for SIRS; however, a recent study addressed cases of individuals with SIRSnegative severe sepsis [53]. Moreover, recently, the definition of sepsis was revised, the new definition consist in a systemic respo ...
... severe sepsis definition includes, among other factors, the presence of two or more criteria for SIRS; however, a recent study addressed cases of individuals with SIRSnegative severe sepsis [53]. Moreover, recently, the definition of sepsis was revised, the new definition consist in a systemic respo ...
Systems Biotechnology of Pseudomonas putida for the enhanced
... and their influence on PHA synthesis in P. putida KT2442, chemostat cultures were employed to perform well-controlled nutrient limitations. Strict nitrogen-limiting condition reached the highest PHA productivity in standard continuous cultivation ever reported. To gain insight into the PHA machinery ...
... and their influence on PHA synthesis in P. putida KT2442, chemostat cultures were employed to perform well-controlled nutrient limitations. Strict nitrogen-limiting condition reached the highest PHA productivity in standard continuous cultivation ever reported. To gain insight into the PHA machinery ...
UNIVERSITAT ROVIRA I VIRGILI CODON USAGE ADAPTATION IN PROKARYOTIC GENOMES
... Translational selection and highly expressed genes Since the first nucleic acid sequences were sequenced and compared, several hypotheses about the evolution of genes and genomes have been proposed. Today, with the availability of a vast amount of sequences of proteins, genes and even genomes from a ...
... Translational selection and highly expressed genes Since the first nucleic acid sequences were sequenced and compared, several hypotheses about the evolution of genes and genomes have been proposed. Today, with the availability of a vast amount of sequences of proteins, genes and even genomes from a ...
Analysis of the Arabidopsis rsr4-1/pdx1
... point mutation in a member of the PDX1/SOR1/SNZ (for Pyridoxine biosynthesis protein 1/Singlet oxygen resistant 1/Snooze) family that leads to reduced vitamin B6 content. Consequently, metabolism is broadly altered, mainly affecting amino acid, raffinose, and shikimate contents and trichloroacetic a ...
... point mutation in a member of the PDX1/SOR1/SNZ (for Pyridoxine biosynthesis protein 1/Singlet oxygen resistant 1/Snooze) family that leads to reduced vitamin B6 content. Consequently, metabolism is broadly altered, mainly affecting amino acid, raffinose, and shikimate contents and trichloroacetic a ...
The Bacterial Toxin RelE Displays Codon
... At a RelE concentration four times less than the concentration of ribosomes that were competent in dipeptide formation (Zavialov et al., 2001; Experimental Procedures), peptide synthesis from the mRNA with UAG as stop codon was completely blocked by the toxin. With twenty times less RelE than active ...
... At a RelE concentration four times less than the concentration of ribosomes that were competent in dipeptide formation (Zavialov et al., 2001; Experimental Procedures), peptide synthesis from the mRNA with UAG as stop codon was completely blocked by the toxin. With twenty times less RelE than active ...
Osmo- and thermo-adaptation in hyperthermophilic Archaea
... total pool of compatible solutes was lower than in the parental strain, but increased notably at salinities above 4.5% NaCl, reaching a value of 3.34 μmol/mg protein at 6.0% NaCl. In response to salt stress, A. fulgidus VC-16S accumulated mainly diglycerol phosphate, an osmolyte thus far confined to ...
... total pool of compatible solutes was lower than in the parental strain, but increased notably at salinities above 4.5% NaCl, reaching a value of 3.34 μmol/mg protein at 6.0% NaCl. In response to salt stress, A. fulgidus VC-16S accumulated mainly diglycerol phosphate, an osmolyte thus far confined to ...
Calreticulin, a multi-process calcium
... More recently, calnexin was shown to perform an important role during rhodopsin maturation and photoreceptor cell survival [34]. Mutations in Drosophila calnexin result in severe disruption of rhodopsin expression, as well as aberrant cytoplasmic Ca2+ levels, indicating a role for calnexin during Ca ...
... More recently, calnexin was shown to perform an important role during rhodopsin maturation and photoreceptor cell survival [34]. Mutations in Drosophila calnexin result in severe disruption of rhodopsin expression, as well as aberrant cytoplasmic Ca2+ levels, indicating a role for calnexin during Ca ...
Lessons from the Genome Sequence of Neurospora crassa: Tracing
... Department of Plant Pathology, University of California, Riverside, California 925211; Department of Chemistry, California State Polytechnic University, Pomona, California 917682; Department of Plant Pathology and Microbiology, Faculty of Agricultural, Food and Environmental Quality Sciences, The He ...
... Department of Plant Pathology, University of California, Riverside, California 925211; Department of Chemistry, California State Polytechnic University, Pomona, California 917682; Department of Plant Pathology and Microbiology, Faculty of Agricultural, Food and Environmental Quality Sciences, The He ...
3 Citrate metabolism and aroma compound production in lactic acid
... the conversion of citrate into lactate, since it was observed that in these microorganisms high amounts of diacetyl are formed (reviewed in [2]). The metabolic biosynthetic pathway from citrate to diacetyl was revealed in L. diacetylactis by use of nuclear magnetic resonance (NMR) techniques [4, 5]. ...
... the conversion of citrate into lactate, since it was observed that in these microorganisms high amounts of diacetyl are formed (reviewed in [2]). The metabolic biosynthetic pathway from citrate to diacetyl was revealed in L. diacetylactis by use of nuclear magnetic resonance (NMR) techniques [4, 5]. ...
Powerpoint
... Facts About MnSOD Protein Most MnSODs from eukaryotes are homotetramers with four subunits and a total molecular weight of ~88 kDa. ...
... Facts About MnSOD Protein Most MnSODs from eukaryotes are homotetramers with four subunits and a total molecular weight of ~88 kDa. ...
Nicotinamide adenine dinucleotide homeostasis and
... molecule that is used by different pathways involved in the regulation of energy metabolism (Sirtuins), response to oxidative stress (PARP, Sirtuins) and Ca2+ signaling (CD38), setting NAD+ as a major regulatory hub directly interfacing energy metabolism and cellular functions (Figure 1). NAD+-depen ...
... molecule that is used by different pathways involved in the regulation of energy metabolism (Sirtuins), response to oxidative stress (PARP, Sirtuins) and Ca2+ signaling (CD38), setting NAD+ as a major regulatory hub directly interfacing energy metabolism and cellular functions (Figure 1). NAD+-depen ...
Nicotinamide adenine dinucleotide, a metabolic regulator of
... with this notion, components of the salvage pathway, such as Npt1p, are localised primarily to the nucleus, whereas components of the de novo pathway reside evenly throughout the cell and have no effect on silencing [14,15]. NAD also regulates gene expression at other genomic loci. Clock/BMAL1 and ...
... with this notion, components of the salvage pathway, such as Npt1p, are localised primarily to the nucleus, whereas components of the de novo pathway reside evenly throughout the cell and have no effect on silencing [14,15]. NAD also regulates gene expression at other genomic loci. Clock/BMAL1 and ...
METABOLIC CUES AND REGULATORY PROTEINS
... Table 2.4. Subset of repressed genes in the letST311M mutant as compared to WT .............................................................................................................56 Table 2.5. Induced genes for letST311M vs. WT at ODs 2 and 3 ......................................57 Table 2 ...
... Table 2.4. Subset of repressed genes in the letST311M mutant as compared to WT .............................................................................................................56 Table 2.5. Induced genes for letST311M vs. WT at ODs 2 and 3 ......................................57 Table 2 ...
Genome-wide Investigation of Cellular Functions for tRNA Nucleus
... cytoplasm for their essential role in protein synthesis. This export event was thought to be unidirectional. Surprisingly, several lines of evidence showed that mature cytoplasmic tRNAs shuttle between nucleus and cytoplasm and their distribution is nutrient-dependent. This newly discovered tRNA ret ...
... cytoplasm for their essential role in protein synthesis. This export event was thought to be unidirectional. Surprisingly, several lines of evidence showed that mature cytoplasmic tRNAs shuttle between nucleus and cytoplasm and their distribution is nutrient-dependent. This newly discovered tRNA ret ...
Mechanisms of animal diapause: recent
... this remains to be demonstrated. The mechanisms associated with this effect have not been fully characterized, but they must act downstream of all three genetic pathways that control dauer entry, as the suppression has not been shown to be pathwayspecific. AMPK as a downstream effector. Just as DAF- ...
... this remains to be demonstrated. The mechanisms associated with this effect have not been fully characterized, but they must act downstream of all three genetic pathways that control dauer entry, as the suppression has not been shown to be pathwayspecific. AMPK as a downstream effector. Just as DAF- ...
Global transcriptional control by glucose and
... Clostridium difficile. About 18% of all C. difficile genes are regulated by glucose, for which 50% depend on CcpA for regulation. The CcpA regulon comprises genes involved in sugar uptake, fermentation and amino acids metabolism, confirming the role of CcpA as a link between carbon and nitrogen path ...
... Clostridium difficile. About 18% of all C. difficile genes are regulated by glucose, for which 50% depend on CcpA for regulation. The CcpA regulon comprises genes involved in sugar uptake, fermentation and amino acids metabolism, confirming the role of CcpA as a link between carbon and nitrogen path ...
and Rhizobiales-Like PPP-Family Protein Phosphatases from
... elucidate the evolutionary, biochemical, cellular and biological characteristics of two recently identified PPP-family protein phosphatase subclasses from the model photosynthetic Eukaryote Arabidopsis thaliana. These two subclasses included the Shewanella-like (SLP1 and 2) and Rhizobiales-like (RLP ...
... elucidate the evolutionary, biochemical, cellular and biological characteristics of two recently identified PPP-family protein phosphatase subclasses from the model photosynthetic Eukaryote Arabidopsis thaliana. These two subclasses included the Shewanella-like (SLP1 and 2) and Rhizobiales-like (RLP ...
The Genera Staphylococcus and Macrococcus
... possibility of false-negative reactions due to PCR inhibitors that might be present in some foods. Several conventional procedures for isolating S. aureus from foods are described below. Nonselective Enrichment Procedures It is often necessary to use nonselective enrichment procedures for the detect ...
... possibility of false-negative reactions due to PCR inhibitors that might be present in some foods. Several conventional procedures for isolating S. aureus from foods are described below. Nonselective Enrichment Procedures It is often necessary to use nonselective enrichment procedures for the detect ...
Trichomonas vaginalis - Università degli Studi di Sassari
... Trichomoniasis is the most common non-viral, curable, STD worldwide that annually affects millions of people[1]. The causative agent of infection is Trichomonas vaginalis, obligate extracellular mucosal parasite that induce significant health sequelae in both men and women. In women, symptoms range ...
... Trichomoniasis is the most common non-viral, curable, STD worldwide that annually affects millions of people[1]. The causative agent of infection is Trichomonas vaginalis, obligate extracellular mucosal parasite that induce significant health sequelae in both men and women. In women, symptoms range ...
Emerging role of Nrf2 - Discovery
... upon challenge with agents causing oxidative stress. Moreover, cells deficient in Nrf2 are much more sensitive to the toxicity of oxidants of various types and cannot be protected by Nrf2 inducers, which, under the same conditions, provide efficient and long-lasting protection to WT cells [29,36,37]. ...
... upon challenge with agents causing oxidative stress. Moreover, cells deficient in Nrf2 are much more sensitive to the toxicity of oxidants of various types and cannot be protected by Nrf2 inducers, which, under the same conditions, provide efficient and long-lasting protection to WT cells [29,36,37]. ...
Functional genomics analysis of the effects of co- decarboxylase/ornithine decarboxylase
... studied with a comprehensive functional genomics approach. The study was preceded by various assays to determine the treatment dosage that would result in complete cytostasis, without non-specific chemical cytotoxicity. The results obtained revealed that the cytostatic mechanism with growth arrest o ...
... studied with a comprehensive functional genomics approach. The study was preceded by various assays to determine the treatment dosage that would result in complete cytostasis, without non-specific chemical cytotoxicity. The results obtained revealed that the cytostatic mechanism with growth arrest o ...