Regulation of Cytochrome bd Expression in Mycobacterium
... (hypoxia) seem to be conditions that are likely to prevail in vivo and that initiate a shifting towards a NRP state (153). Tubercle bacilli reside inside granulomas of the human host and those appear to build a hypoxic environment for the bacteria (130). This seems to be inconsistent with the classi ...
... (hypoxia) seem to be conditions that are likely to prevail in vivo and that initiate a shifting towards a NRP state (153). Tubercle bacilli reside inside granulomas of the human host and those appear to build a hypoxic environment for the bacteria (130). This seems to be inconsistent with the classi ...
Regulation of Starch Synthesis in Cassava Yona Baguma
... of PP2A, did not, suggesting that sugar and ABA signaling pathways converge at the PP1 level downstream of the sugar signaling pathway. Chloramphenicol, which specifically inhibits plastid de novo protein synthesis, with or without sucrose, blocked sbe expression but cycloheximide, a cytosolic de no ...
... of PP2A, did not, suggesting that sugar and ABA signaling pathways converge at the PP1 level downstream of the sugar signaling pathway. Chloramphenicol, which specifically inhibits plastid de novo protein synthesis, with or without sucrose, blocked sbe expression but cycloheximide, a cytosolic de no ...
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... may account for many cellular effects of these mycotoxins. Sphinganineis a useful sphingolipid-biomarker as an early clinical indicator of exposure to fumonisins and related mycotoxins. ...
... may account for many cellular effects of these mycotoxins. Sphinganineis a useful sphingolipid-biomarker as an early clinical indicator of exposure to fumonisins and related mycotoxins. ...
AngelasPPT
... MOI for 1 hour (to allow one round of infection) Why at high MOI? So each cell can be infected by both mutants am2- ...
... MOI for 1 hour (to allow one round of infection) Why at high MOI? So each cell can be infected by both mutants am2- ...
Cyclic-‐di-‐AMP: another second messenger enters the fray
... can be found in the Pfam database (Table S1)22. The majority of these proteins are found in bacterial species but a small number are also present in archaea within the Euryarchaeota ...
... can be found in the Pfam database (Table S1)22. The majority of these proteins are found in bacterial species but a small number are also present in archaea within the Euryarchaeota ...
SURVEY AND SUMMARY A profusion of upstream open reading
... the downstream AdoMetDC ORF, thereby increasing AdoMetDC activity and polyamine levels rise. When polyamine levels are excessive, the scanning 43S preinitiation complex ignores the weaker tiny uORF AUG and recognizes the stronger small uORF AUG, resulting in translation of the small uORF and sequenc ...
... the downstream AdoMetDC ORF, thereby increasing AdoMetDC activity and polyamine levels rise. When polyamine levels are excessive, the scanning 43S preinitiation complex ignores the weaker tiny uORF AUG and recognizes the stronger small uORF AUG, resulting in translation of the small uORF and sequenc ...
Metabolic decision making by protein-metabolite - ETH E
... contribution of specific transcription factors and global transcriptional regulation to E. coli’s gene expression. Using the L‐arginine biosynthesis pathway as an example, we show that global transcriptional regulation sets each promoter’s maximal capacity in a lar ...
... contribution of specific transcription factors and global transcriptional regulation to E. coli’s gene expression. Using the L‐arginine biosynthesis pathway as an example, we show that global transcriptional regulation sets each promoter’s maximal capacity in a lar ...
Identification of genes specifically required for the
... a hypothetical protein, whereas Gmet 2410 and Gmet 3229 are predicted to encode a superoxide dismutase, and a thioredoxinrelated protein, respectively. The strain in which Gmet 2833 was deleted was deficient in phenol metabolism as well as benzene metabolism (Figure 2), indicating that this gene of ...
... a hypothetical protein, whereas Gmet 2410 and Gmet 3229 are predicted to encode a superoxide dismutase, and a thioredoxinrelated protein, respectively. The strain in which Gmet 2833 was deleted was deficient in phenol metabolism as well as benzene metabolism (Figure 2), indicating that this gene of ...
Potassium starvation responses in yeast highlight novel potassium-related functions
... cells to the proper redox state. Yeast cells growing on ammonium as nitrogen source but lacking potassium accumulate large amounts of intracellular ammonium, which is transported through Trk1 taking advantage of the chemical similarity of both cations. Ammonium accumulation activates the retrograde ...
... cells to the proper redox state. Yeast cells growing on ammonium as nitrogen source but lacking potassium accumulate large amounts of intracellular ammonium, which is transported through Trk1 taking advantage of the chemical similarity of both cations. Ammonium accumulation activates the retrograde ...
A systems biology approach sheds new light on the regulation of
... supported the view that acid resistance involves a mechanism based on the transcriptional switch between the expression of genes encoding aerobic and anaerobic enzymes and controlled by the two-component system (TCS) regulator OmpR. Model validation confirmed this hypothesis and provided the means t ...
... supported the view that acid resistance involves a mechanism based on the transcriptional switch between the expression of genes encoding aerobic and anaerobic enzymes and controlled by the two-component system (TCS) regulator OmpR. Model validation confirmed this hypothesis and provided the means t ...
Gene Section GAST (gastrin) Atlas of Genetics and Cytogenetics
... The two principal biologically active forms of circulating gastrin are gastrin-17 (G17) and gastrin-34 (G34). In rodent and human G cells of antrum and proximal duodenum, approximately 95% of the progastrin is processed to partially sulfated G17 (85%) and G34 (10%). Although G17 is the predominant p ...
... The two principal biologically active forms of circulating gastrin are gastrin-17 (G17) and gastrin-34 (G34). In rodent and human G cells of antrum and proximal duodenum, approximately 95% of the progastrin is processed to partially sulfated G17 (85%) and G34 (10%). Although G17 is the predominant p ...
Minimal metabolic pathway structure is consistent with
... We also used correlation analysis with E. coli pathway gene sets to assess consistency with co-regulation by the same TF (Fig 2F). The pathways share over 6,700 co-regulated gene pairs within E. coli metabolism. Our analysis quantitatively revealed two levels of regulation. First, local regulation ( ...
... We also used correlation analysis with E. coli pathway gene sets to assess consistency with co-regulation by the same TF (Fig 2F). The pathways share over 6,700 co-regulated gene pairs within E. coli metabolism. Our analysis quantitatively revealed two levels of regulation. First, local regulation ( ...
The deleterious effect of missense mutations on pre
... Genetic diseases are characterized by the presence of mutations that inactivate single genes. The sequence analysis of the corresponding candidate disease genes allows confirmation of diagnosis or realization of genetic testing in family members. Whenever sequence variants are found during routine g ...
... Genetic diseases are characterized by the presence of mutations that inactivate single genes. The sequence analysis of the corresponding candidate disease genes allows confirmation of diagnosis or realization of genetic testing in family members. Whenever sequence variants are found during routine g ...
Regulators of Ubiquitin Dependent Protein Degradation in the
... split into two independent open reading frames encoding the N- and C-terminal part (candA-N, candA-C) of the mammalian homolog. Deletion of the single or both candA genes leads to mutants with identical phenotypes. They produce only few asexual spores, are blocked in early sexual development and app ...
... split into two independent open reading frames encoding the N- and C-terminal part (candA-N, candA-C) of the mammalian homolog. Deletion of the single or both candA genes leads to mutants with identical phenotypes. They produce only few asexual spores, are blocked in early sexual development and app ...
Cloning of adiponectin receptors that mediate antidiabetic metabolic
... without permeabilization (Fig. 2c). These data indicate that AdipoR1 and AdipoR2 are integral membrane proteins—the N terminus was internal and the C terminus was external, which is opposite to the topology of all the reported GPCR families17–19. Expression of AdipoR1 or AdipoR2 at the cell surface ...
... without permeabilization (Fig. 2c). These data indicate that AdipoR1 and AdipoR2 are integral membrane proteins—the N terminus was internal and the C terminus was external, which is opposite to the topology of all the reported GPCR families17–19. Expression of AdipoR1 or AdipoR2 at the cell surface ...
Multiple Functions of the New Cytokine
... two transcription and translation variants: a long form (lfTSLP) that is induced by inflammation, and a short, constitutively-expressed form (sfTSLP), that appears to be downregulated by inflammation. The TSLP forms can be produced by a number of cell types, including epithelial and dendritic cells ...
... two transcription and translation variants: a long form (lfTSLP) that is induced by inflammation, and a short, constitutively-expressed form (sfTSLP), that appears to be downregulated by inflammation. The TSLP forms can be produced by a number of cell types, including epithelial and dendritic cells ...
EP 1790660 B1
... [0021] A protein is typically divided into notional domains by aligning it with known sequences in databases and then determining regions of the protein which show different alignment patterns from each other. [0022] The method is preferably used for the expression of protein 287. This protein can b ...
... [0021] A protein is typically divided into notional domains by aligning it with known sequences in databases and then determining regions of the protein which show different alignment patterns from each other. [0022] The method is preferably used for the expression of protein 287. This protein can b ...
Nature inspired platforms for production of acetyl
... IDH1, deleted. In these studies, we profiled changes in central metabolism arising from the expression of Aspergillus nidulans ACL genes, aclA and aclB, in the host wild type S. cerevisiae strain and in the BY4742 ∆IDH1 strain. We have chosen to utilize IDH1 deleted cells, which have previously been ...
... IDH1, deleted. In these studies, we profiled changes in central metabolism arising from the expression of Aspergillus nidulans ACL genes, aclA and aclB, in the host wild type S. cerevisiae strain and in the BY4742 ∆IDH1 strain. We have chosen to utilize IDH1 deleted cells, which have previously been ...
"Using the KEGG Database Resource". In: Current Protocols in
... 2. There are many analyses that can be done with the Ortholog Table. For example, under the Organism column, each entry has links to “P | G | T” corresponding to Pathway, Genome, and Title. “P” links to the pathway map, “G” to the genome map, and “T” to a list of gene functions. Clicking “P” will in ...
... 2. There are many analyses that can be done with the Ortholog Table. For example, under the Organism column, each entry has links to “P | G | T” corresponding to Pathway, Genome, and Title. “P” links to the pathway map, “G” to the genome map, and “T” to a list of gene functions. Clicking “P” will in ...
Unveiling the physiological and molecular basis of Mycobacterium
... species, namely M. tuberculosis, the main etiological agent of human tuberculosis (TB), and M. bovis, the causative agent of bovine tuberculosis (bTB), one of the most relevant zoonosis in the world. The complex pathogenesis of MTC bacteria is influenced by several factors, including host and bacter ...
... species, namely M. tuberculosis, the main etiological agent of human tuberculosis (TB), and M. bovis, the causative agent of bovine tuberculosis (bTB), one of the most relevant zoonosis in the world. The complex pathogenesis of MTC bacteria is influenced by several factors, including host and bacter ...
Ma et al 2009 - HKUST Institutional Repository
... transient in real time, via the PIM review software. To estimate the fold Ca2+ rise of each Ca2+ transient, the PIM review software was used to determine the relative photon intensity (photons/pixel) of a cell or group of cells during a particular Ca2+ transient, as well as from the same cell or cel ...
... transient in real time, via the PIM review software. To estimate the fold Ca2+ rise of each Ca2+ transient, the PIM review software was used to determine the relative photon intensity (photons/pixel) of a cell or group of cells during a particular Ca2+ transient, as well as from the same cell or cel ...
Chlamydia Exploit the Mammalian Tryptophan-Depletion
... transporters of the TyrP family that have high-Trp content. Thus, import of Trp is self-limiting in ...
... transporters of the TyrP family that have high-Trp content. Thus, import of Trp is self-limiting in ...
Ciliary neurotrophic factor may activate mature
... delivery of the cytokine had led us to hypothesize either that CNTF did not spread freely far away from these sites or that a high concentration of the cytokine was required. The present in vitro results strongly support the latter hypothesis since, in sharp contrast to the results obtained in short ...
... delivery of the cytokine had led us to hypothesize either that CNTF did not spread freely far away from these sites or that a high concentration of the cytokine was required. The present in vitro results strongly support the latter hypothesis since, in sharp contrast to the results obtained in short ...
Expanded roles of leucine-responsive regulatory protein in
... et al., 2002). A certain proportion of the regulated genes are involved, as originally proposed, in transport and metabolism of amino acids, but Lrp has also been suggested to regulate genes involved in biosynthesis and degradation of various metabolites other than amino acids (Brinkman et al., 2003 ...
... et al., 2002). A certain proportion of the regulated genes are involved, as originally proposed, in transport and metabolism of amino acids, but Lrp has also been suggested to regulate genes involved in biosynthesis and degradation of various metabolites other than amino acids (Brinkman et al., 2003 ...
VAAM-Jahrestagung 2015 1.–4. März in Marburg/Lahn
... numerous authors of oral and poster presentations for their contributions to this conference. We are very thankful to our main sponsors and industrial partners, as well as the German Research Foundation (DFG), the Federation of European Microbiological Societies (FEMS) and the local DFG-funded Colla ...
... numerous authors of oral and poster presentations for their contributions to this conference. We are very thankful to our main sponsors and industrial partners, as well as the German Research Foundation (DFG), the Federation of European Microbiological Societies (FEMS) and the local DFG-funded Colla ...