Download SUZ12 antibody - middle region (ARP32515_P050)

SUZ12 antibody - middle region (ARP32515_P050)
Data Sheet
Product Number
Product Name
Size
Gene Symbol
Alias Symbols
Nucleotide Accession#
Protein Size (# AA)
Molecular Weight
Product Format
NCBI Gene Id
Host
Clonality
Official Gene Full Name
Gene Family
ARP32515_P050
SUZ12 antibody - middle region (ARP32515_P050)
50ug
SUZ12
CHET9; JJAZ1; KIAA0160
NM_015355
739 amino acids
83kDa
Lyophilized powder
23512
Rabbit
Polyclonal
Suppressor of zeste 12 homolog (Drosophila)
ZNF
Description
This is a rabbit polyclonal antibody against SUZ12. It was validated on Western Blot using a cell lysate as a
positive control. Aviva Systems Biology strives to provide antibodies covering each member of a whole protein
family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a
target protein. For availability of antibody needed for your experiment, please inquire ().
Target Reference
Li,H., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (50), 20001-20006
Partner Proteins
Description of Target
Additional Information
Blocking Peptide
Immunogen
Lead Time
EGFR, STAT3, ELK4, SRF, KHSRP, JAG1, JUN, JUN, RELA, ATF2, ATF7, BATF, BCL3, CEBPG, COBRA1,
CSNK2A1, CSNK2A2, DDIT3, EEF1D, ELK1, ELK4, EPHB2, ETS1, FOS, GATA4, GTF2F2, HNF1A, JUN,
JUNB, JUND, LMNA, MAF, MAP3K7, MAPK1, MITF, NCOA1, NCOR2, NFATC3, NFKB1, OPTN, PRKACA,
PSMC5, RB1, RELA, RPS6KA1, RPS6K
A chromosomal aberration involving SUZ12 may be a cause of endometrial stromal tumors. Translocation t
(7;17)(p15;q21) with JAZF1 generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1
and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in
endometrial stromal sarcomas, where it is rarer.This zinc finger gene has been identified at the breakpoints of a
recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these
breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc
finger domain in the C terminus of the coding region. The specific function of this gene has not yet been
determined. Publication Note: This RefSeq record includes a subset of the publications that are available for
this gene. Please see the Entrez Gene record to access additional publications.
IHC Information: Paraffin embedded placenta tissue, tested with an antibody dilution of 5 ug/ml.
For anti-SUZ12 antibody is Catalog # AAP32515 (Previous Catalog # AAPP03518)
The immunogen for anti-SUZ12 antibody: synthetic peptide directed towards the middle region of human SUZ12
Domestic: within 24 hours delivery International: 3-5 business days
Peptide Sequence
Synthetic peptide located within the following region:
TGETNDKSTAPIAKPLATRNSESLHQENKPGSVKPTQTIAVKESLTTDLQ
Reconstitution and
Storage
Swissprot Id
Protein Name
Add 50 ul of distilled water. Final anti-SUZ12 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose.
For longer periods of storage, store at -20C. Avoid repeat freeze-thaw cycles.
Sample Type
Confirmation
Protein Accession #
Purification
Species Reactivity
Application
Predicted Homology
Based on Immunogen
Sequence
Q15022
Polycomb protein SUZ12
SUZ12 is strongly supported by BioGPS gene expression data to be expressed in HeLa
NP_056170
Affinity Purified
Human, Pig, Bovine, Mouse, Dog, Horse, Rabbit, Rat, Guinea pig
CHIP, IHC, WB
Dog: 100%; Pig: 100%; Rat: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Bovine: 100%; Rabbit: 100%;
Guinea pig: 93%
Human Placenta
Image 1
Placenta
HCT116
Chromatin Immunoprecipitation
(ChIP) Using SUZ12 antibody middle region (ARP32515_P050)
and HCT116 Cells
Image 2
Human HeLa
WB Suggested Anti-SUZ12 Antibody Titration: 0.21 ug/ml
Positive Control: Hela cell lysate
Image 3
SUZ12 is strongly supported by BioGPS gene
expression data to be expressed in Human HeLa cells
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This product is for Research Use Only. Not for diagnostic, human, or veterinary use.
Optimal conditions of its use should be determined by end users.