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Constitution relations in biological cells Ludger Jansen Institut für Philosophie Universität Rostock UNIVERSITÄT ROSTOCK | PHILOSOPHISCHE FAKULTÄT Applied Ontology This talk Ontology of Cells Theory of Constitution The Ontology of Cells The Ontology of Cells What the dictionary says „An autonomous self-replicating unit (in principle) that may constitute an organism (in the case of multi-cellular organisms) in which individual cells may be more or less specialised (differentiated) for particular functions. All living organisms are composed of one or more cells.“ Art. „cell“, in: J M Lackie, J A T Dow (eds.), The Dictionary of Cell Biology, 2nd ed., 1995, p. 54. What the NCIT says (1) • • • • Definition: Any small compartment. Preferred Name: Cell Other Properties: Semantic_Type Spatial Concept What the NCIT says (2) • Definition: The smallest units of living structure capable of independent existence, composed of a membraneenclosed mass of protoplasm and containing a nucleus or nucleoid. • NCI-GLOSS Definition: The individual unit that makes up all of the tissues of the body. All living things are made up of one or more cells. To be discussed 1. Modes of Being 2. Levels of Being 3. Constitution Modes of Being • „Seinsarten“ vs. „Aktionsarten“ – Ensemble nouns – Mass nouns – Set nouns – Proper nouns – Count nouns – Collective nouns Masses/Sets Masses Sets Individuals Individual/Collectives Collectives Simon C. Dik, The Theory of Functional Grammar. Part 1: The Structure of the Clause, 2nd rev. ed., Berlin/New York: Mouton de Gruyter 1997, Kap. 6.3.2 und 7.3.1 Beef CowSTUFF Cow Herd CowCOLL HerdGRAIN Mass Individual Collective Beef CowSTUFF Steak BeefPIECE Mass Portion Modes of Being • • • • Individuals Masses Collectives Portions of masses To be discussed 1. Modes of Being 2. Levels of Being 3. Constitution Living Beings Living Being 1 living being 1 kind of living being At least 10 000 different kinds of macromolecules 106 to 109 individual cells Source: Mayr 1984, 109. Levels of Partition • • • • • • • Organisms Organs Cells Organels Molecules Atoms Elementar particles Has_part Has_part To be discussed 1. Modes of Being 2. Levels of Being 3. Constitution A cell or an organism? A cell that constitutes an organism! What is Constitution? Examples • • • • • The lump and the statue Logs and stones and the house The piece of paper and the 10-Euro-note The letters and the word The body and the person Material Constitution • x materially constitutes y at t if and only if there are primary kinds F and G such that at t: – x has F as its primary kind and y has G as its primary kind. – x and y are spatially coincident and there is no other thing that has G as its primary kind and is spatially coincident with x. – x is in G-favorable circumstances. – Necessarily, for everything that has F as its primary kind and is in G-favorable circumstances there is some spatially coincident entity that has G as its primary kind. – Possibly, x exists but no spatially coincident entity that has G as its primary kind. – If x is of one basic kind of stuff, then y is of the same basic kind of stuff. Source: Baker 2007 Identity vs. Constitution • If spatial, then necessary spatial coincidence • Semi-contingent spatial coincidence • Creates levels • Strong unity relation • Weak unity relation • Equivalence relation • No equiv. relation – Reflexive – Symmetric – Transitive – Irreflexive – Asymmetric – Transitive Constituted_by • G is (materially) constituted by F iff F and G are primary kinds such that for every y there is some x such that : – x has F as its primary kind and – y has G as its primary kind and – x materially constitutes y. Examples • • • • • Statue constituted_by Lump Block_house constiuted_by LogCOLL 10-Euro-note constituted_by PaperPIECE Word constituted_by LetterCOLL Person constituted_by Body Constitutes • F (materially) constitutes G iff F and G are primary kinds such that for every x there is some y such that : – x has F as its primary kind and – y has G as its primary kind and – x materially constitutes y. Cells are not necessarily parts of living beings! Pseudo-Examples • • • • • * Lump constitutes Statue * LogCOLL constitutes Block house * PaperPIECE constitutes 10-Euro-note * LetterCOLL constitutes Word * Body constitutes Person • Remember the semi-contingent nature of material constitution! Grain relations – Goldatom grain_of GoldatomCOLL – Cell grain_of CellCOLL Constitution relations – Goldstatue constituted_by GoldatomCOLL – Living being constituted_by CellCOLL But not * Goldatom grain_of Goldstatue * Cell grain_of Living being • Mereological relations between particulars – Head #2 part_of Goldstatue #1 – Cell membrane #343 part_of Cell #57 • Mereological relations between universals – Cell membrane part_of Cell – For every cell membrane there is some cell such that the grains of the molecule-collective that constitutes the cell membrane are also grains of the molecule-collective that constitutes the cell.