Download Chapter 11 Review - Blue Valley Schools

Name: ______________________
Chapter 11 Review
_____ 1 Which of these is a receptor molecule? (Figure 1)
_____ 2 A signal transduction pathway is initiated
when a _____ binds to a receptor.
A G protein
B cyclic AMP
C tyrosine kinase
D signal molecule
_____ 3 Which of these is a signal molecule? (Figure 1)
_____ 4 A signal molecule is also known as a(n) _____.
A
B
C
D
key
ligand
protein
receptor
Figure 1
_____ 5 Which of these receptors is NOT a membrane receptor?
(Figure 2)
_____ 6 Which of these is a G-protein-linked receptor? (Figure 2)
_____ 7 Which of these is a receptor tyrosine kinase? (Figure 2)
_____ 8 Which of these is an ion-channel receptor? (Figure 2)
Figure 2
_____ 9 The binding of signal molecules to _____ results in the phosphorylation of tyrosines. (Figure 2)
_____ 10 Which of these receptor molecules would allow Na+ to flow into the cell? (Figure 2)
_____ 11 Which of these extracellular signal molecules could diffuse through a plasma membrane and bind to an
intracellular receptor?
A glucose
B glycerol
C cellulose
D estrogen
_____ 12 A(n) _____ is an example of a signal molecule that can bind to an intracellular receptor and thereby cause a
gene to be turned on or off.
A ion
B steroid
C protein
D nucleic acid
E carbohydrate
_____ 13
_____ is a signal molecule that binds to an intracellular receptor. (Figure 2)
_____ 14 Thyroid hormones bind to _____ receptors.
A
B
C
D
intracellular
tyrosine-kinase
G-protein-linked
plasma membrane ion-channel
_____ 15 Which of these acts as a second messenger? (Figure 3)
_____ 16 Which of these acts as a second messenger?
A
B
C
D
G protein
cyclic AMP
protein kinase
G-protein-linked receptor
_____ 17 Calcium ions that act as second messengers are stored in _____.
A
B
C
D
Figure 3
lysosomes
peroxisomes
mitochondria
endoplasmic reticula
_____ 18 In this signal transduction pathway (Figure 4), phospholipase C catalyzes the production of IP3, which then
opens an ion channel that releases _____ into the cell's ________.
A Na+ ... nucleus
B Ca2+ ... cytoplasm
C IP3 ... peroxisomes
D adenylyl cyclase ... cytosol
_____ 19 A protein kinase activating many other protein
kinases is an example of _____.
A mutualism
B deactivation
C sensitization
D amplification
_____ 20 The cleavage of glycogen by glycogen phosphorylase
releases _______.
A cellulose
B glucose-1-phosphate
C fructose-1-phosphate
D nothing: glycogen phosphorylase cannot cleave glycogen
Figure 4
_____ 21 As shown here (Figure 5), epinephrine acts as a
signal molecule that attaches to _____ proteins.
A ion-channel receptor
B intracellular receptor
C receptor tyrosine kinase
D G-protein-linked receptor
Figure 5
_____ 22 In this signal transduction pathway (Figure 6),
a flood of calcium ions activates a protein called
calmodulin, which triggers the assembly of _________
that alter the shape of the cell.
A ribosomes
B microtubules
C microfilaments
D DNA molecules
_____ 23 Which of these is NOT correct?
A
B
C
D
Figure 6
Calcium ions can act as second messengers.
Kinases are enzymes that phosphorylate other molecules.
Intracellular receptors can be found on the surface of a cell's plasma membrane.
Ion channels are found on both the plasma membrane and the endoplasmic reticulum.
_____ 24 A toxin that inhibits the production of GTP would interfere with the function of a signal transduction pathway
that
A
B
C
D
is initiated by the binding of a signal molecule to _____ receptors.
ion-channel
intracellular
G-protein-linked
receptor tyrosine kinase
_____ 25 Which of these is a logical signal transduction pathway?
A
B
An ion-channel receptor opens, allowing a steroid hormone to enter the cell; the steroid hormone then
activates protein kinases that convert GTP to GDP, which binds to an intracellular enzyme that carries out
a response.
A G-protein-linked receptor activates G protein, which activates phospholipase C, which cleaves a
membrane protein to form IP3, which binds to a calcium channel on the ER, which opens to release
calcium ions into the cytoplasm, which bind to an intracellular enzyme that carries out a response.