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CELL SPECIALIZATION Chapter 7 Section 4 EQ: Why do cells in multicellular organisms become specialized? Some cells send signals Most are chemical signals ◦ hormones ◦ neurotransmitters Target cells receive the signal ◦ Have receptors either on outer side of cell membrane or inside cell (if signal can cross membrane) Receiving Signals Receptor proteins ◦ Bind only signals that match specific shape of its binding site ◦ Once signal molecule binds to receptor site receptor protein changes shape which relays “message” to the target cell Responding to Signals The cell may respond to a signal by: ◦ ◦ ◦ ◦ Changing its membrane permeability Activating enzymes Causing a second messenger to form Second messenger is a molecule that is generated when a specific signal attaches to a receptor protein; it causes a change in cell function Neurotransmitter Serotonin Animation http://highered.mcgrawhill.com/olcweb/cgi/pluginpop.cgi?it=swf::5 35::535::/sites/dl/free/0072437316/ CELL SPECIALIZATION Stem Cells: type of cell that gives rise to all types of cells in that organ system During embryonic development, cells not only increase in #, but also undergo differentiation becoming specialized in structure & function Cell Differentiation Cell Specialization Columnar Cells Cuboidal Cells Squamous Cells Neurons Why do some cells become neurons & others become red blood cells? Why do some cells become neurons & others become red blood cells? Different genes are “turned on” so specialization happens