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Chapter 11: Intro to Genetics 11-3 Other Patterns of Inheritance Intro • After showing that alleles segregate, Mendel also wondered if they do so independently of each other. • Does the segregation of one pair of alleles affect the segregation of another pair of alleles? Ex: Does the gene for seed shape have anything to do with the gene for seed color? Does a round seed always have to be yellow? • To answer this question, Mendel performed an exp (2 factor cross) and followed 2 different genes. Independent Assortment • What was Mendel’s experiment? • The two factor cross. • 1st Mendel crossed true breeding plants that produced only round yellow peas (RRYY) with plants that produced wrinkled green peas (rryy) • All offspring=round yellow peas. • Yellow round were dominant over wrinkled green. • Did not show if genes assort independently. Provides plants needed for next cross. Independent Assortment • All plants were heterozygous (RrYy) • Mendel wanted to know if the 2 dominant genes would stay together or separate. He crossed RrYy with RrYy. • See fig 11-10 pg 271 • Results: 556 seeds produced, 315 round yellow, 32 wrinkled green, 209 had combos of phenotypes not found in either parent. • This meant the allele for shape segregated independently for color—this was known as. independent assortment. Independent Assortment • What is the principle of independent assortment? • Genes for different traits can segregate independently during the formation of gametes. Independent assortment helps account for the many genetic variations observed in plants, animals, and other organisms. A Summary of Mendel’s Principles • How can Mendel’s principles be summarized? • Inheritance of biological characteristics is determined by genes which are passed from parents to offspring. • When 2+ forms of gene for single trait exits, some alleles are dominant & some are recessive. • Each adult has 2 copies of each gene—one from each parent. These genes are segregated from each other when gametes are formed. • Alleles for diff genes segregate independently of each other. Beyond Dominant & Recessive • Do all genes show a simple pattern of dominant and recessive? • NO! Genetics is more complicated in most organisms because the majority of genes have more than 2 alleles. • Many important traits are controlled by more than 1 gene. • Some alleles are neither dominant or recessive, and many traits are controlled by multiple genes or multiple alleles. Beyond Dominant & Recessive • What are the different patterns of inheritance? • Incomplete Dominance • Codominance • Multiple Alleles • Polygenic traits Beyond Dominant & Recessive • What is incomplete dominance? • One allele is not completely dominant over another. The heterozygous phenotype is somewhere in between the 2 homozygous phenotypes. – A cross between red and white flowered plants produce pink colored flowers. Beyond Dominant & Recessive • What is codominance? • Both alleles contribute to the phenotype of the organism. • Ex: In chickens, the allele for black feathers is codominant with the allele for white feathers. • Heterozygous chickens are speckled with black and white feathers. Beyond Dominant & Recessive • What are multiple alleles? • Genes have more than 2 alleles. • Does not mean that the individual has more than 2 alleles. It means that more than 2 possible alleles exist in a population. • Ex: Coat color in rabbits. A rabbit’s coat color is determined by a single gene that has four different alleles. • Ex: Human genes for blood type, eye color in humans Beyond Dominant & Recessive • What are polygenic trait? • Two or more genes control a trait. • Three genes are involved in making the reddishbrown pigment in the eyes of fruit flies. • Polygenic traits show a wide range of phenotypes. • Ex: skin color in humans—more than 4 diff genes control this trait. Applying Mendel’s Principles • Do Mendel’s principles only apply to plants? • No! In the 1900s, Thomas Hunt Morgan, a geneticist, decided to look for a model organism to study genetics. • He wanted an animal that was small, easy to keep in a lab, and able to produce large numbers of offspring in a short period of time. • He chose the fruit fly (Drosophila melanogaster) • Mendel’s principles also apply to humans. Genetics & Environment • Are the characteristics of organisms determined solely by genetics? • NO! Characteristics are determined by the interaction between genes and the environment. • Ex: Genes may affect the height of a plant. These characteristics are also influenced by climate, soil conditions, & availability of water. • Genes provide the plan, but how the plan unfolds also depends on environment.