Download 2002

ASSIGNMENT BOOKLET
Bachelor’s Degree Programme in Science
(B.Sc.)
Cell Biology (LSE-01)
ASSIGNMENTS 2002
ASSIGNMENT-1 TMA
ASSIGNMENT-2 CMA
SCHOOL OF SCIENCES
Indira Gandhi National Open University
Maidan Garhi
New Delhi – 110 068
LSE-01
LSE-01
Assignments 1 and 2
2002
Dear Students,
As explained in the Programme Guide for B.Sc, you will have to do 2 assignments for the elective course
LSE – 01. One of the assignments is Tutor Marked (TMA) and the other is Computer Marked (CMA). The
blockwise distribution of assignments is as follows:
Assignment – 1 (TMA)
Assignment – 2 (CMA)
Block 1 to 4
Block 1 to 4
The instructions for doing the assignments are provided in the Programme Guide under Section 7.1
Assignment. You should read the instructions carefully before you start doing these assignments.
Please submit your assignments as follows:
Assignment No.
Assignment – 1 (TMA)
Assignment – 2 (CMA)
Date of Submission
12 weeks after receiving the printed
material with assignments.
12 weeks after receiving the printed
material with assignments.
Answer sheets received after the due date shall not be accepted.
We strongly suggest that you retain a copy of your assignments.
Wishing you all good luck.
2
Where to Send
The Coordinator of your study centre
The Director (SR&E),
Indira Gandhi National Open
University,
Maidan Garhi,
New Delhi – 110068.
ASSIGNMENT – 1
(Tutor Marked Assignment)
Course Code : B.Sc./LSE-01
Assignment Code : LSE-01/AST-1/TMA-1/2002
Max. Marks : 100
1.
a)
Give short answer to the following questions.
i)
ii)
iii)
iv)
Name an eucaryote in which mitochondria are absent.
Which protobiont model was proposed by Alexander Oparin?
State one important difference between procaryotic and eucaryotic DNA.
List two changes in the environment that resulted from evolution of water
splitting photosynthesis.
b)
i)
ii)
2.
3.
4.
5.
6.
7.
(1)
(1)
(1)
(2)
What is the difference between resolving power and magnifying power of a
microscope?
Explain fluorescence microscopy.
(2)
(3)
a)
Antibodies are used to localise the specific molecule in cell. How?
(5)
b)
Explain polymorphism in lysosomes.
(5)
a)
Describe the process of column chromatography for separating biomolecules.
(5)
b)
List the lipid components of biomembranes and discuss their organisation in these
biomembranes.
(5)
a)
Differentiate between the following:
i) Free Diffusion and Osmosis
ii) Facilitated Diffusion and Active Transport
(2½2)
b)
Calculate the permeability of the membrane when the concentration difference
across the membrane is 0.1 moles/lit and the rate of the movement of the substance
across the membrane is 106 mole/cm2/sec.
(5)
a)
With the help of examples discuss the specificity of enzymes with respect to the
nature of the reaction they catalyse.
(2½)
b)
How is enzyme activity controlled by covalent modulation of enzymes?
(2½)
a)
Describe briefly the two main phases of cellular respiration.
(Hint: with and without oxygen use)
(10)
b)
Outline the functional interrelationship between catabolism and anabolism.
(5)
a)
Explain, how DNA is organized in chromosomes?
(5)
b)
Describe the replication of DNA and the location of enzymes involved in DNA
replication.
(5)
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8.
Discuss briefly the role of calcium ions as second messenger.
9.
a)
List the four factors which are considered important in controlling the cell division. (2)
b)
Explain briefly the molecular theory of genetic recombination.
(3)
What are cell junctions? Compare between tight junctions and gap junctions.
(5)
b)
Draw a neat and labelled diagram of nerve cell.
(3)
c)
Differentiate between bone and cartilage.
(2)
10. a)
(5)
11. What is the role of meristematic tissues in plants? Compare the mitotic division in plant
and animal cells.
(5+5)
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ASSIGNMENT – 2
(Computer Marked Assignment)
Course Code : B.Sc./LSE-01
Assignment Code : LSE-01/AST-2/CMA-1/2002
Max. Marks : 100
1.
Which of the following is on the borderline of life between living and non-living organisms?
1) Green bacteria
2) Eubacteria
3) Purple bacteria
4) TMV
2.
Which of the following organelle is common to both procaryotes and eucaryotes?
1) Ribosomes
2) Nucleus
3) Mitochondria
4) Lysosomes
3.
‘Power house’ of the cell is
1) Chloroplast
2) Lysosomes
3) Mitochondria
4) Peroxisomes
4.
If you want to examine the patterns of capillaries in a section of skin, which microscope will
you use?
1) LM
2) TEM
3) SEM
4) Phase contrast microscope
5.
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P is used as tracer of
1) Protein metabolism
2) Salt metabolism
3) Heme synthesis
4) Nucleic acid metabolism
6.
Which of the following plastids store carbohydrate in the form of starch?
1) Chloroplast
2) Leucoplast
3) Chromoplast
4) Amyloplast
7.
Under pathological conditions, which form of lysosomes are found in abundance?
1) Primary lysosomes
2) Secondary lysosomes
3) Residual bodies
4) Autophagic vacuoles
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8.
A cell with extensive network of RER is actively involved in
1) Protein synthesis
2) Lipid metabolism
3) ATP production
4) Formation of cell plate
9.
Cysteine is a monomer of
1) carbohydrates
2) lipids
3) nucleic acids
4) proteins
10. A single carboxyl group and a long non-polar hydrocarbon chain is the characteristic of
1) nucleoside
2) amino acid
3) fatty acid
4) pyrimidine
11. The unique properties of water that make it necessary for life is due to its
1) pH
2) solvent nature
3) molecular structure
4) dissociation constant
12. Phosphate group of the nucleotide can form an ester bond with both the 3 and 5 OH group
of pentose sugar and the bond is known as
1) Hydrogen bond
2) Covalent bond
3) Phosphodiester bond
4) Electrovalent bond
13. Terpenes is synthesized by polymerization of five carbon unit called
1) isoprene unit
2) lecithin unit
3) cephalin unit
4) phosphatidylserine unit
14. In -chains of protein collagen every third molecule is
1) proline
2) glycine
3) lysine
4) hydroxy-proline
15. The cellulose molecule is a linear chain because the glucose molecules are linked by
1) 1 – 4 glycosidic bonds
2) 1 – 4 glycosidic bonds
3) peptide bonds
4) intermolecular hydrogen bonds
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16. Membrane fluidity increases with increase in temperature because
1) cholesterol prevents the binding of hydrocarbon chains.
2) it becomes more permeable to water and other molecules.
3) fatty acyl side chains undergo transition from get like state to a mobile state.
4) the lateral movement of integral proteins increases.
17. The osmotic pressure of one molar aluminium chloride in water at 30C would be
1) 9976.8 J litre1
2) 11006.5 J litre1
3) 10076.5 J litre1
4) 2519.1 J litre1
18. A solution having higher osmotic pressure than the other is called as
1) Hyperosmotic
2) Hypoosmotic
3) Isoosmotic
4) Hypertonic
19. What do you call the small hydrophobic protein molecules which dissolve in the lipid bilayer
and increase the ion permeability of the bilayer?
1) Chromophore
2) Ionophore
3) Uniport
4) Symport
20. Where does oxidative phosphorylation occur in a cell?
1) Chloroplast
2) Mitochondrion
3) Leucoplast
4) Golgybody
21. Activation energy
1) helps the substrate to bind with the enzymes.
2) is the energy required by the reaction to start.
3) is the energy required to break the energy barrier to start a reaction.
4) is enhanced by the enzymes in biological systems.
22. The enzymes that transfer hydrogen to a molecule other than oxygen are called
1) oxidases
2) transferases
3) hydrolases
4) dehydrogenases
23. Michaelis constant depends one the
1) pH
2) enzyme concentration
3) susbtrate concentration
4) temperature
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24. Operan model explains the
1) genetic control of enzymes in prokaryotes.
2) genetic control of enzymes in eukaryotes.
3) genetic control of feed back inhibition.
4) synthesis of substrate and specific enzyme.
25. The conversion of digestive enzymes from their inactive forms to active form in the gut
lumen is an example of
1) hormone regulation
2) compartmentation
3) genetic control
4) covalent modulation
26. In biosystems isotopic form of an element is used for
1) making subcellular fractions
2) perfusion of the organs
3) creating abnormalities in the organisms
4) labelling the metabolite to trace its course
27. Which one of the following is responsible for the stimulation of glycolysis?
1) Citrate
2) NADH
3) ADP
4) Alanine
28. The enzyme acyl dehydrogenase is involved in
1) protein metabolism
2) glycolysis
3) fatty acid degradation
4) None of the above
29. Which of the following are used during biosynthesis in organisms?
1) ATP and NAD
2) ADP and NAD
3) ATP and NADPH
4) ATP and Oxygen
30. Which of the following differences between glycogen and starch is correctly stated?
1) The monomeric units in glycogen are glucose and in starch cellulose.
2) Glycogen is a linear polymer while starch is branched.
3) Starch is a mixture of cellulose and amylose and glycogen contains amylose and
amylopectin.
4) All are incorrect
31. During gluconeogenesis
1) the molecules of glucose are synthesised from the carbon skeleton of amino acids,
lactate and glycerol
2) glucose is broken down into glycerol and pyruvate
3) the excess of glucose is secreted in the cells
4) none of the above
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32. Which of the following is not a component of nucleosomes:
1) H2A
2) H1
3) H4
4) 300 bp of DNA
33. RNA is transcribed from DNA by
1) DNA polymerase
2) RNA polymerase
3) Elongation factor G
4) Poly (A) polymerase
34. The higher levels of chromatin are maintained by histone
1) H2A
2) H2B
3) H1
4) H4
35. The nuclear contents are separated from the cytoplasm by two concentric complex
membranes surrounding the nucleus. These membranes are termed as:
1) perinuclear space
2) nuclear lamina
3) nuclear envelop
4) nuclear matrix
36. Enzyme Polymerases are involved in
1) Sealing of DNA fragments
2) Replication of DNA
3) Cutting of DNA segments
4) Organisation of DNA
37. Neuroregulators are the signalling molecules that fall into the category of
1) neurotransmitters
2) hormones
3) local chemical mediaters
4) none of the above.
38. Signalling mediated by steroid hormones requires
1) cell surface receptors
2) intracellular receptors
3) second messenger
4) cyclic AMP
39. Chemotactic responses are the reactions of unicellular organisms to extracellular signals in
which
1) receptoer-down regulation occurs due to target cell desensitization.
2) cells moves towards or away from a specific chemical substance present in the
environment.
3) second messenger binds to specific protein in the cell and alters its conformation.
4) calcium ions are released from internal storage.
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40. In which phase of cell division most of the protein and RNA synthesis occurs?
1) Interphase
2) Prophase
3) Anaphase
4) Metaphase
41. In which stage of meiotic cell division synapsis or pairing of chromosomes occurs?
1) Leptotene
2) Zygotene
3) Pachytene
4) Diplotene
42. In which stage of meiosis formation of chiasmata occurs?
1) Zygotene
2) Pachytene
3) Diplotene
4) Diakinesis
43. Aggregation of slime mold amoeba occurs
1) as a response to cyclic AMP synthesized by starving cells.
2) due to the need for reproduction.
3) as a result of a cyclic phenomenon of life cycle.
4) due to migration of the cells.
44. Plasmodesmata are the
1) tight junctions
2) gap junctions in the animals
3) desmosomes in the plants
4) communicating junctions in plants
45. Which one of the following is not the protein found in extracellular matrix of animals?
1) Chondronectin
2) Glycosaminoglycans
3) Collagen
4) Fibronectin
46. Hard bone without any space is called as
1) Spongy bone
2) Compact bone
3) Replacing bone
4) Dermal bone
47. White blood cells with pear shaped large nucleus are
1) Monocytes
2) Lymphocytes
3) Basophils
4) Thrombocytes
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48. Cartilage with transparent and homogenous matrix is called
1) Fibrous cartilage
2) Calcified cartilage
3) Elastic cartilage
4) Hyaline cartilage
49. Which of the following tissues is found in hard seeds, nuts and stony fruits of plants?
1) Xylem
2) Phloem
3) Sclerenchyma
4) Collenchyma
50. The carbohydrate which clogs the sieve plates at the end of growing season and during
winter but gets dissolved during spring is
1) cellulose
2) callose
3) hemicellulose
4) pectin
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