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Transcript
From Gene to Protein
Chapter Questions
7) Which of the following represents a similarity between RNA and DNA?
A) Both are double-stranded.
B) the presence of uracil
C) the presence of an OH group on the 2' carbon of the sugar
D) nucleotides consisting of a phosphate, sugar, and nitrogenous base
E) Both are found exclusively in the nucleus.
13) A particular triplet of bases in the template strand of DNA is AGT. The corresponding codon for the mRNA
transcribed is
A) AGT.
B) UGA.
C) TCA.
D) ACU.
E) either UCA or TCA, depending on wobble in the first base
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The following questions refer to Figure 17.1, a table of codons.
Figure 17.1
2
15) What amino acid sequence will be generated, based on the following mRNA codon sequence?
5'AUG-UCU-UCG-UUA-UCC-UUG
A) met-arg-glu-arg-glu-arg
B) met-glu-arg-arg-gln-leu
C) met-ser-leu-ser-leu-ser
D) met-ser-ser-leu-ser-leu
E) met-leu-phe-arg-glu-glu
17) What is the sequence of a peptide based on the mRNA sequence 5' UUUUCUUAUUGUCUU 3' ?
A) leu-cys-tyr-ser-phe
B) cyc-phe-tyr-cys-leu
C) phe-leu-ile-met-val
D) leu-pro-asp-lys-gly
E) phe-ser-tyr-cys-leu
19) A particular eukaryotic protein is 300 amino acids long. Which of the following could be the maximum number
of nucleotides in the DNA that codes for the amino acids in this protein?
A) 3
B) 100
C) 300
D) 900
E) 1,800
20) A codon
A) consists of two nucleotides.
B) may code for the same amino acid as another codon.
C) consists of discrete amino acid regions.
D) catalyzes RNA synthesis.
E) is found in all eukaryotes, but not in prokaryotes.
21) If the triplet CCC codes for the amino acid proline in bacteria, then in plants CCC should code for
A) leucine.
B) valine.
C) cystine.
D) phenylalanine.
E) proline.
43) A particular triplet of bases in the coding sequence of DNA is AAA. The anticodon on the tRNA that binds the
mRNA codon is
A) TTT.
B) UUA.
C) UUU.
D) AAA.
E) either UAA or TAA, depending on first base wobble.
3
45) What is an anticodon part of?
A) DNA
B) tRNA
C) mRNA
D) a ribosome
E) an activating enzyme
Figure 17.2
48) Figure 17.2 represents tRNA that recognizes and binds a particular amino acid (in this instance, phenylalanine).
Which codon on the mRNA strand codes for this amino acid?
A) UGG
B) GUG
C) GUA
D) UUC
E) CAU
4
52) Where is eukaryotic ribosomal RNA transcribed?
A) the Golgi apparatus
B) ribosomes
C) the nucleolus
D) X chromosomes
E) prokaryotic cells only
54) The function of the ribosome in polypeptide synthesis is to
A) hold mRNA and tRNAs together.
B) catalyze the addition of amino acids from tRNAs to the growing polypeptide chain.
C) move along the mRNA and eject tRNAs during the translocation process.
D) A and B only
E) A, B, and C
60) As a ribosome translocates along an mRNA molecule by one codon, which of the following occurs?
A) The tRNA that was in the A site moves into the P site.
B) The tRNA that was in the P site moves into the A site.
C) The tRNA that was in the P site moves to the E site and is released.
D) The tRNA that was in the A site departs from the ribosome.
E) Both A and C are correct.
Each of the following is a modification of the sentence THECATATETHERAT.
A.
B.
C.
D.
E.
THERATATETHECAT
THETACATETHERAT
THECATARETHERAT
THECATATTHERAT
CATATETHERAT
72) Which of the above is analogous to a frameshift mutation?
73) Which of the above is analogous to a single substitution mutation?
5
75) A frameshift mutation could result from
A) a base insertion only.
B) a base deletion only.
C) a base substitution only.
D) deletion of three consecutive bases.
E) either an insertion or a deletion of a base.
77) Which point mutation would be most likely to have a catastrophic effect on the functioning of a protein?
A) a base substitution
B) a base deletion near the start of a gene
C) a base deletion near the end of the coding sequence, but not in the terminator codon
D) deletion of three bases near the start of the coding sequence, but not in the initiator codon
E) a base insertion near the end of the coding sequence, but not in the terminator codon
6