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... acids in two-carbon units. These two carbon molecules form acetyl-CoA. The newly created acetyl-CoA from pyruvate or beta-oxidation of fats can be oxidised to carbon dioxide (CO2) in the tricarboxylic acid cycle (TCA). The critical aspect of the TCA cycle is producing hydrogen atoms for transport to ...
video slide
video slide

... by NADH, forming lactate as an end product, with no release of CO2 • Lactic acid fermentation by some fungi and bacteria is used to make cheese and yogurt • Human muscle cells use lactic acid fermentation to generate ATP when O2 is scarce ...
Pg. ___ 4/28 Daily Catalyst
Pg. ___ 4/28 Daily Catalyst

... A) Unicellular organisms that live in freshwater, such as amoeba, must pump out excess water using their contractile vacuole B) The enzyme lactase binds with lactose to produce molecules of glucose and galactose C) Electrons escaping from chlorophyll a are replaced by those released by the hydrolysi ...
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... The Kreb’s cycle takes place inside the matrix of mitochondria. It is also called aerobic respiration. The acetyl – coA enters the Kreb’s Cycle, undergoes a series of changes and is oxidized to CO2 and H2 O liberating energy. (i) Formation of Citric Acid: In presence of condensation enzyme Citrate S ...
Download PDF
Download PDF

... The goal of this course is to learn about general aspects of biochemical pathways from the perspective of the chemical principles and chemical reactions. We will cover: 1. Biochemical structures. We will study detailed aspects of the three-dimensional structure of proteins, and how this translates i ...
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Aerobic & Anaerobic Metabolism in Muscles

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... 22. Most lipids are made of ______________ acids. Describe their shape. What functional group is found on the head end of the molecule? 23. Are both ends of a fatty acid polar? Explain. 24. Hydrophilic means water ___________. Which end of a fatty acid is hydrophilic? The non-polar end of a fatty a ...
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... • Pyruvate can be a source of new glucose – Store energy as glycogen – Generate NADPH via pentose phosphate pathway • Pyruvate can be a source of acetyl-CoA – Store energy as body fat – Make ATP via citric acid cycle • Acetyl-CoA stimulates glucose synthesis by activating pyruvate carboxylase ...
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Pentose Phosphate Pathway - Lectures For UG-5

... • No ATP is directly consumed or produced in the cycle. Carbon one of glucose 6-phosphate is released as CO2, and two NADPH are produced for each glucose 6-phosphate molecule entering the oxidative part of the pathway. • The rate and direction of the reversible reactions of the pentose phosphate pat ...
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Citric acid cycle



The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP). In addition, the cycle provides precursors of certain amino acids as well as the reducing agent NADH that is used in numerous other biochemical reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest established components of cellular metabolism and may have originated abiogenically.The name of this metabolic pathway is derived from citric acid (a type of tricarboxylic acid) that is consumed and then regenerated by this sequence of reactions to complete the cycle. In addition, the cycle consumes acetate (in the form of acetyl-CoA) and water, reduces NAD+ to NADH, and produces carbon dioxide as a waste byproduct. The NADH generated by the TCA cycle is fed into the oxidative phosphorylation (electron transport) pathway. The net result of these two closely linked pathways is the oxidation of nutrients to produce usable chemical energy in the form of ATP.In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondrion. In prokaryotic cells, such as bacteria which lack mitochondria, the TCA reaction sequence is performed in the cytosol with the proton gradient for ATP production being across the cell's surface (plasma membrane) rather than the inner membrane of the mitochondrion.
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