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Transcript
Question one Multiple choice questions (MCQs) Q1 The sum of all chemical and energy transformations that take place in the organism is: (a) Anabolism (b) Metabolism (c) Catabolism (d) Non of the above Answer B Q2 The phase of metabolism in which larger molecules are split into smaller ones is : (a) Catabolism (b) Anabolisam (c) Metabolism (d) Non of the above Answer A Q3 The glycolysis is the name given to the pathway involving the conversion of: (a) glycogen to glucose-6-phosphate (b) glucose to pyruvate or lactate (c) glycogen or glucose to fructose (d) glucose or fatty acids to pyruvate or acetyl CoA Answer B Q4 The conversion of one molecule of glucose to two molecules of pyruvate results in the net formation of: (a) six molecules of water (b) two molecules of ATP (c) three molecules of ATP (d) thirty-eight molecules of ATP Answer B Q5 The enzymes of citric acid cycle are located in the: (a) mitochondrion (b) nucleus (c) cytoplasm (d) lysosomes Answer A Question Read each sentence. Mark (T) if it is true. Mark (F) if it is false Q1 Uridine diphosphate glucose (UDPG) can be formed directly from UDP- galactose by the enzyme UDP-glucose 4-epimerase Q2 The process of fatty acid biosynthesis shows several features which distinguish it clearly from fatty acid oxidation, these include the requirement for NADPH and biotin Q3 The pentose phosphate pathway leads to the production of glucose 1-phosphate for glycogen synthesis Q4 The pentose phosphate pathway includes two reversible oxidative reactions followed by a series of reversible sugar phosphate interconversions Q5 The enzyme α-amylase if absent from the pancreatic secretion, results in incomplete digestion of starch result in a large bacterial population in the faeces and diarrhoea T T F F T Fill in the blanks DNA is the information storage mRNA is the information carrier Protein is the information product The monomeric units of nucleic acids are nucleotide Nucleosides contain monosaccharide, D-ribose or 2-deoxy-D-ribose, linked to N-1 of pyrimidine or N-9 of purines, by a o-glycosidic linkage Each nucleotide contains nitrogen base, sugar and phosphate DNA contains the purine bases: adenine, guanine and pyrimidine bases Thymine, Cytosine RNA contains Uracil instead of thymine In contrast to DNA which is organized into two strands, RNA is single strand structure Three major types of RNA are mRNA, tRNA and rRNA all are involved in some aspects of protein synthesis DNA is the major store of heredity information which is copied into RNA molecules in a process called transcription, proteins are then synthesized in a process involving the translation of RNA Q1 Below is a diagram showing the β-oxidation of fatty acid, Choose the most appropriate answer of the following questions Q1 What are the types of fatty acid: (a) Saturated even noumber fatty acid (b) Saturated odd numbere fatty acid (c) Unsaturated even number fatty acid Answer A Q2 How fatty acids are activated in preparation of oxidation? (a) Fatty acid are activated to their coenzyme A derviative (b) Fatty acid are activated to their coenzyme B derviative (c) Fatty acid are activated to their coenzyme C derviative Answer A Q3 Answer What is the enzyme for this activation? (a) Fatty acyl CoA synthease (b) Fatty acyl CoA synthetase (c) Fatty acid synthetase B Q4 What are the coenzymes nedded for fatty acid oxidation? (a) FAD (b) FAD and NAD (c) NAD Answer B Q5 What is the function of carnitine? (a) transfers fatty acids from mitochondria to cytosol (b) transfers amino acids from cytosol to mitochondria (c) transfers fatty acids from cytosol to mitochondria Answer C Q6 Where (a) (b) (c) Answer C Q7 Where (a) (b) (c) is β-oxidation taking place? In cytosol Ine doplasmic reticulum In mitochondria are the products during each cycle of β-oxidation of fatty acid? Acetyl CoA Acetyl CoA and FADH2 Acetyl CoA, FADH2 and NADH Answer C Q8 What are the energy producing steps in β-oxidation pathway? (a) Steps 1 and 2 (b) Steps 1 and 3 (c) Steps 2 and 3 Answer B Q9 β-oxidation of fatty acids involves a sequence of four reactions repeated several times. This sequence is best described by: (a) Oxidation, oxidation, hydration and cleavage (b) Oxidation, hydration, oxidation and cleavage (c) Oxidation, hydration, hydration and cleavage Answer B Q 10 What are fate of acetyl CoA? (a) Oxidation in citric acid cycle (b) Cholesterol synthesis (c) All of the above Answer C Q 11 Number of β-oxidation cycles undergo a 16 carbon saturated fatty acid: (a) 8 (b) 7 (c) 6 Answer A Q 12 The breakdown of the fatty acid CH3-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CO2H via the β-oxidation pathway would yield (a) three mol acetyl units and one mol propionyl units (b) four mol acetyl units and one mol propionyl units (c) four mol acetyl units and one mol Co2 units Answer A Q 13 How many ATPs are produced when palmitoyl-CoA, a 16 carbon saturated fatty acid is oxidized completely to Co2 and H2O? (a) 129 (b) 131 (c) 96 Q 14 The sequence of reactions below occurs, in the appropriate direction, in: -CH2-CH2↔ CH=CH- ↔ -CHOH-CH2- ↔ -COCH2 (a) fatty acid oxidation/biosynthesis (b) the TCA cycle (c) glycolysis Answer A Answer A Answer the following short questions Q1 Identify the deoxyribose, phosphate groups and different nitrogenous bases nitrogenous bases phosphate groups deoxyribose Adenine cytosine Guanine Thymine Q2 The figure shows two mechanisms by which an RNA polymerase can attach to its promoter. Identify which mechanism is used by bacterial RNA polymerase and which is used by RNA polymerase II of eukaryotes A B