Download Name____________________________ DNA Investigation

Name____________________________
DNA Investigation: Transcription, Translation, and Mutation
Transcription:
#1) www-class.unl.edu/biochem/gp2/m_biology/animation/gene/gene_a2.html
(Transcription Animation #2 on my website)
 Use website #1 to answer the following questions after watching the animation:
1—Which region of the gene acts as the “light switch” to turn on transcription?
2—What molecule “unwinds” the DNA during transcription?
3—After the mRNA strand is synthesized and travels to the cytoplasm, what happens to the
“unzipped” DNA strand in the nucleus?
Translation:
#2) www-class.unl.edu/biochem/gp2/m_biology/animation/gene/gene_a3.html
(Translation Animation #1 on my website)
 Use website #2 to answer the following questions after watching the animation:
4—What is the first step of protein synthesis called?
5—What is the second step of protein synthesis called? What happens during this step?
6—What three nitrogen bases make up the “start codon”? ___ ___ ___
7—What type of chemical bond joins together the amino acids in the chain that is produced during
translation?
Use your notes, GOOGLE, and/or your own knowledge to answer the following ?s:
8—What is the first amino acid on the chain made during any act of translation?
9—What does the Release Factor do? What three codons call for the release factor?
Mutation:
#3) learn.genetics.utah.edu/archive/sloozeworm/mutationbg.html
(Mutations #1 on my website)
#4) www.genetichealth.com/G101_Changes_in_DNA.shtml
(Mutations #2 on my website)
 Use website #3 to answer the following questions:
10—What are the two processes that usually cause DNA mutations. Briefly EXPLAIN each
process.
1)
2)
11—List three environmental agents that can damage DNA and cause mutations by modifying
nucleotide bases.
1)
2)
3)
12—Other than modifying nucleotide bases, how else can environmental agents alter DNA?
13—How often does DNA polymerase make a mistake during replication to cause a mutation?
14—How can a cell “fix” potential DNA mutations?
 Use website #4 to answer the following questions:
15—List 5 different types of DNA mutations.
1)
2)
3)
4)
5)
16---Find a website online that covers DNA, Replication, Transcription, Translation, and/or
Mutations that is NOT listed on this sheet. Create 5 of your own “webquest” questions based on
this website and write down the web address.
Additional Genetics Resources:
Visit www.nature.ca/genome/04/041/041_e.cfm and try out the genetics games. Let me know if
they are helpful!!!