Download Genetics

Genetics
Why your family is
messed up?
Gregor Mendel
Father of Modern
Genetics
Pea Plants
Monk
Gregor Mendel
Alternative versions of
genes (alleles) account
for variation
Gregor Mendel
For Each Character, an
organism inherits two
alleles
Gregor Mendel
If the two alleles are
different, One is
dominant and one is
recessive
Gregor Mendel
The two alleles
segregate during
gamete production
Sex-linked
On the X chromosome
Colorblindness
Hemophilia
Muscular dystrophy
Sex Influenced
On a autonomic chromosome but affected
by what sex you are
Male pattern baldness
Blood Types
Blood Types
Linked Genes
On a autonomic chromosomes near each
other
Red hair / freckles
Pleiotropy
One gene has multiple effects
Sickle-cell anemia
Epistasis
A gene at one location alters the phenotypic
expression of a gene on a second location
Fur color
Polygenic
Characters vary in a population along a
continuum
Skin Color
Recessively Inherited Traits
Must inherit genes from both parents to
display trait
Albinism
Tay-Sachs
Cystic Fibrosis
Dominately Inherited Traits
Must inherit genes from only one parents to
display trait
Achondroplasia
Huntington’s disease
Fetal Testing
Nondisjunction
Aneuroploidy
Human Disorders
Down’s Syndrome
Turner’s Syndrome
Klinefelter’s Syndrome
Trisomy X Syndrome
Cloning
Changes in Spatial Pattern
Homeobox
Changes in Spatial Pattern
Homeotic Genes
(Hox Genes)
position information
Changes in Spatial Pattern
Changes in Spatial Pattern
Changes in
expression
patterns of four
Hox genes over
time
Stem Cells
A Cell that’s job has not been determined
Early embryonic Stem Cells
Blastocyst Embryonic Stem Cells
Fetal Stem Cells
Umbilical Stem Cells
Adult Stem Cells
Stem Cells
For each new application of stem cell technology,
we must consider:
What are the benefits?
What are the risks?
Whom will the technology help? Does it have the
potential to hurt anyone?
What does this mean for me? For my family? For
others around me?
Why might others not share my view?
Stem Cells
Ethical, legal and social issues.
Ethical issues are those that ask us to consider the
potential moral outcomes of stem cell technologies.
Legal issues require researchers and the public to help
policymakers decide whether and how stem cell
technologies should be regulated by the government.
Social issues involve the impact of stem cell
technologies on society as a whole.
Cancer Causing Genes
Oncogenes
Proto-oncogene
Tumor Suppressor Genes
Faulty Tumor Suppressor Genes