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Organic macromolecules Intro to organic molecules • Organic molecules contain carbon. • Many organic molecules are made of chains, i.e. polymers. – Polymers are large molecules made up of repeating molecular units. • The repeated units are small molecules called monomers. – Some monomers have other functions of their own. • Cells join smaller organic molecules together to form larger molecules. • These larger molecules, macromolecules, may be composed of thousands of atoms and weigh over 100,000 amu. • The four major classes of macromolecules are: carbohydrates, lipids, proteins, and nucleic acids. Carbohydrates carbohydrates.asx Carbohydrates • All are composed of carbon, hydrogen, and oxygen in a 1:2:1 ratio. • All sugars are carbohydrates. • Glucose is a monosaccharide. • Sucrose is a disaccharide. • Starch and cellulose are polysaccharides. • Two monosaccharides can join with a glycosidic linkage to form a disaccharide via dehydration. For example, maltose, malt sugar, is formed by joining two glucose molecules. Sucrose, table sugar, is formed by joining glucose and fructose and is the major transport form of sugars in plants. • Starch is a storage polysaccharide composed entirely of glucose monomers. • Plants store starch within plastids, including chloroplasts. • Plants can store surplus glucose in starch and withdraw it when needed for energy or carbon. • Animals that feed on plants, especially parts rich in starch, can also access this starch to support their own metabolism. Cellulose Fig. 5.8 • Monosaccharides, particularly glucose, are a major fuel for cellular work. Energy is stored in their chemical bonds, which holds the carbons together. • They also function as the raw material for the synthesis of other monomers, including those of amino acids and fatty acids. Fig. 5.4 Proteins Proteins • All protein molecules contain Carbon, Hydrogen, Oxygen, and Nitrogen. • Proteins are long chains of amino acids. • There are a total of 20 amino acids. Fats Fats • Fats are made from mostly Carbon and Hydrogen, with a small amount of Oxygen. • Lipid is another name for a fat. • They are made from fatty acids and one glycerol unit. • The major function of fats is energy storage. • A gram of fat stores more than twice as much energy as a gram of a polysaccharide. • Humans and other mammals store fats as long-term energy reserves in adipose cells. • Fat also functions to cushion vital organs. • A layer of fats can also function as insulation. • This subcutaneous layer is especially thick in whales, seals, and most other marine mammals. Nucleic Acids Nucleic Acids • Nucleic acids are polymers of monomers called nucleotides. • Nucleic acids include DNA and RNA • Each nucleotide consists of three parts: a nitrogen base, a pentose sugar, and a phosphate group. • While DNA has the information for all the cell’s activities, it is not directly involved in the day to day operations of the cell. –Proteins are responsible for implementing the instructions contained in DNA.