Download Course of Immunology

Course of Immunology
- introduction
(2015/2016)
Marta Sobotková
email:
[email protected]
Course structure
● Lectures
- Presence in lectures is obligatory
- Lectures are held every Tuesday at 8:00-9:40
- Three absences are tolerated, more frequent
absences must be based on official certificate
and will be solved individually
Date
Theme
Teacher
6.10. 2014
Immune system, overview. Phagocytic cells, complement.
Communication between cells of immune systems, adhesion molecules, prof. Špíšek
cytokines.
13.10. 2014
Antigen processing and presentation, HLA I and II class.
prof. Šedivá
20.10. 2014
Specific (adaptive) immunity T and B lymphocytes
PharmDr.Palich
Fučíková
27.10. 2014
Immunity against infection
Adkins
3.11. 2014
Immunodeficiency, vaccination
prof.Šedivá
10.11. 2014
Immunity against tumors.
prof. Špíšek
24.11. 2014
Immunology of transplatation
dr. Kalina
1.12. 2014
Autoimmunity. Immunopathology.
dr. Sobotková
8.12. 2014
Immunopathological reactions, allergy
dr. Kayserová
15.12. 2014
Immunotherapy
dr. Podrazil
5.1. 2015
Clinical aspects of immune disorders
Dr. Horváth
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Course structure
● Seminars
- The first seminar and presentation of your
thesis are compulsory; the time of other
seminars is devoted to self-studying,
preparation of seminar thesis and
consultations with teachers
Seminar thesis
● groups of 1-3 students
● structure of thesis:
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1000 – 2000 words
form of an essay
briefly & concisely & interestingly
Abstract, text and references (literature) are
obligatory, subchapters and discussion are
recommended
●Term of submission: until 30.10.2015
- in the digital form (doc form preffered)
- has to be sent to: [email protected]
Seminar thesis
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Regulatory T cells - function and subtypes
IL-17, its role in pathologic inflammatory process
Immune homeostasis in the gut and oral tollerance
Biology of NKT cells
Toll-like receptors and its function
The role of B lymphocytes and antibodies in antitumor
immunity
Immunology of sepsis
Immunology of coeliac disease.
Pathogenesis of oedema in hereditary angioedema and
targets for acute attack treatment
Mechanisms of dysregulation in humoral
immunodeficiences – CVID as model disease
Presence and future od monoclonal antibodies in allergic
diseases treatment
The newest strategies of cancer immunotherapy.
Oral presentations
- November 18 and 25, time 8.00-9.40 am.
- each thesis will be presented verbally
- range: 8 minutes
- Powerpoint presentation (6-10 slides)
Final appraisal
● Presence on lectures
● Seminar thesis:
fulfilled / not fulfilled
+ verbal appraisal (after presentation)
● Verbal examination:
2 out of 50 questions
Evaluation of the essay:
1/ Adherence to the length limits
2/ Correct content of the essay, no serious
misunderstandings
3/ Satisfactory graphical layout and style of the essay
Other comments:
Evaluation of the verbal presentation:
1/ Adherence to the length limits
2/ Correct content of the essay, no serious
misunderstandings
3/ Satisfactory graphical layout and style of the
presentation
http://imunologie.lf2.cuni.cz/
● shedules
● presentations (download
possible)
● recommended literature, links
● contacts
Citation
„Most of the patients are hemizygous for 22q11.2, some have
defects in various loci on chromosome 10, about 10% of cases
are familial (2, 3)„
Literature / References:
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2.
DRISCOLL DA, SALVIN J, SELLINGER B, et al. Prevalence of 22q11
microdeletions in DiGeorge and velocardiofacial syndromes: implications for
genetic counselling and prenatal diagnosis. J Med Genet 1993: 30: 813-7.
3.
SEDIVA A, BARTUNKOVA J, ZACHOVA R, et al. Early development of
immunity in diGeorge syndrome. Med Sci Monit 2005: 11: 182-7.
Sources
• Bibliographic databases
• Clinical sources online
Pubmed – www.pubmed.com
Medscape - www.emedicine.com
Up-to-date – www.uptodate.com
Orphanet – www.orpha.net
Good luck with Your essays and
presentations !