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SINGAPORE Home › Products › Protein Tools › Protein Kinases › Protein Kinases Protein Kinases Product Listing Product Overview The reversible addition of phosphate groups to proteins is important for the transmission of signals within eukaryotic cells and, as a result, protein phosphorylation and dephosphorylation regulate many diverse cellular processes. As the number of known protein kinases has increased at an ever-accelerating pace, it has become more challenging to determine which protein kinases interact with which substrates in the cell. The determination of consensus phosphorylation site motifs by amino acid sequence alignment of known substrates has proven useful in this pursuit. These motifs can be helpful for predicting phosphorylation sites for specific protein kinases within a potential protein substrate. Learn More Protein Kinases Specificity Featured Products cAMP-dependent Protein Kinase (PKA), catalytic subunit p42 MAP Kinase (MAPK) Glycogen Synthase Kinase 3 (GSK-3) See entire list » Protein Kinase Substrate Recognition Chart Protein Kinase Substrate Recognition Chart NEB offers protein kinases for a number of different specificity motifs. Within each recognition determinant, the phosphoacceptor residue is a serine, threonine or tyrosine.
